Don S. Fredrickson Lipid Research Conference

唐·S·弗雷德里克森脂质研究会议

基本信息

批准号：
10752509
负责人：
Gregory A Graf
金额：
$ 1万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10752509
关键词：
Address Adipose tissue Atherosclerosis Award Basic Science Cardiometabolic Disease Cardiovascular Diseases Classification Clinical Clinical Investigator Collaborations Dedications Development Diabetes Mellitus Doctor of Philosophy Dyslipidemias Ensure Esters Faculty Fatty Acids Fostering Goals Heart Hypertension Hypertriglyceridemia Institution Insulin Resistance Kentucky Lipase Lipids Lipoproteins Metabolic Diseases Metabolic syndrome Metabolism Midwestern United States Mission Modeling Names National Heart, Lung, and Blood Institute North Carolina Obesity Oral Participant Regulation Research Research Activity Research Personnel Research Project Grants Role Rotation Science Scientist Seminal Senior Scientist Students Talents Tangier Disease Technology Thinking Training Triglyceride Metabolism Underrepresented Populations United States National Institutes of Health Universities Wisconsin cardiovascular risk factor career career development clinically significant design early-career faculty experience gut microbiome hydroxy fatty acid innovation insight lectures lipid metabolism lipoprotein lipase medical schools meetings new technology novel strategies posters programs relative cost social social engagement stable isotope symposium translational scientist

项目摘要

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier's Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model and has been hosted by the University of Kentucky ('16, `17, '21), Vanderbilt University ('18, `23), the University of Cincinnati ('19), Duke University and the University of North Carolina ('22). The FLRC will be hosted by the Medical College of Wisconsin in 2024 and return to UK in 2025. Keynote Lectures at the 2023 Fredrickson conference include Barbara Kahn, Harvard University and Alan Remaley, National Heart Lung and Blood Institute. The thematic scientific sessions include: Intestinal Microbiome Control of Lipid Metabolism, Stable Isotope Studies in Lipid Metabolism, Atherosclerosis Regression and Efferocytosis, Modulators of Triglyceride Metabolism & Lipoprotein Lipase. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. In accordance with that mission, the agenda also includes additional scientific sessions dedicated for trainees, a “Poster Pitch” session (5-7, 90-second presentations), and a judged poster session. By design, the agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.

抽象的 Don S. Fredrickson 脂质研究会议 (FLRC) 汇集了科学家和学员研究脂质和脂蛋白代谢对发育和发育的影响 FLRC 是以已故的 Don S. Fredricks 的名字命名的。 1966 年至 1974 年担任国家心脏研究所（现 NHLBI）所长，随后又担任 NIH 制定了血脂异常的临床分类（I-V 型），描述了丹吉尔的疾病，并在脂蛋白代谢方面取得了开创性的发现，最重要的是，他进行了训练。对医学产生巨大影响的基础和临床科学家和从业者脂蛋白代谢领域。自2016年以来，FLRC采用轮流机构主办模式，由肯塔基大学（'16、'17、'21）、范德比尔特大学（'18、'23）、辛辛那提 ('19)、杜克大学和北卡罗来纳大学 ('22) 将是。 2024 年由威斯康星医学院主办，2025 年返回英国。 2023 年弗雷德里克森会议的主题演讲包括哈佛大学的芭芭拉·卡恩 (Barbara Kahn) 和 Alan Remaley，国家心肺和血液研究所的主题科学会议。包括：脂质代谢的肠道微生物组控制、脂质稳定同位素研究代谢、动脉粥样硬化消退和胞吞作用、甘油三酯调节剂代谢和脂蛋白脂肪酶 FLRC 非常重视学生和研究员，早期职业教师和代表性不足的群体根据该使命，议程。还包括专门为学员提供的额外科学课程，“海报推介”课程（5-7， 90 秒的演讲），以及经过评判的海报会议议程设计得涵盖了所有内容。参加培训的学员有机会在舞台上展示他们的研究成果，并与领导者建立联系领域，并扩大他们对脂质代谢研究的范围和理解心脏代谢疾病。我们的形式鼓励各级科学家之间的非正式互动，提供思想交流和合成的创新方法将推动脂质领域的发展由于该计划涵盖基础科学，因此该会议将产生巨大影响。因此，预计这次会议将提供新的发现和临床意义。不仅深入了解脂质代谢的基本方面，还了解如何治疗，并最终治愈多种心脏代谢疾病状态。