MECHANICAL SYSTEMS RENOVATION

机械系统改造

• 批准号: 7935585
• 负责人: HOWARD J. FEDEROFF
• 金额: $ 467.12万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-21 至 2014-12-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7935585
• 关键词: Accreditation; Air; American; Animal Experimentation; Animal Housing; Animal Model; Animals; Caring; Core Facility; Environmental air flow; Equipment; Extramural Activities; Funding; Grant; Gray unit of radiation dose; Health; Humidifier; Institution; Laboratory Animals; Mechanics; Medicine; Mission; National Center for Research Resources; Occupations; Phase; Protocols documentation; Research; Research Personnel; Research Support; Resources; Risk; Sanitation; Side; System; Time; Universities; Wing; Work; aged; animal care; animal resource; comparative; design; exhaust; foot; programs; research study

DESCRIPTION (provided by applicant): The Division of Comparative Medicine (DCM) is the sole centralized animal resource core facility at Georgetown University. The mission of the facility is to provide optimal husbandry and veterinary care, specialized technical support and appropriate regulatory oversight for research studies involving laboratory animals. The 50,740 sq. foot facility actively supports 133 research investigators with 218 animal care and use protocols. The building is comprised of 2 wings - the "Grey" Side and the "Blue" Side, constructed in 1986 and 1995, respectively. Fifty-seven investigators house animals on the Grey Side and utilize research support spaces. In 2006, the University initiated a 3-phase, 5 year plan to replace the 23 year old mechanical systems on the Grey Side. Two NCRR G20 grant projects are currently underway to complete the first 2 planned phases including the replacement of non-operational humidifiers; aged exhaust fans, cage wash equipment and the building management system; and upgrade of the dedicated cage wash facility HV system. This proposal seeks to complete Phase 3 of the institutional long range plan by replacement of 3 air handling units (AHUs) and associated mechanical support equipment. "In-kind" equipment replacement is requested, with all work performed solely in mechanical spaces (4,072 sf). Redundancy of the existing AHUs will allow phased replacement with minimal disruption of ventilation and ongoing research studies. This project embraces sustainable design principles consistent with LEED criteria. American jobs (15-23 FTE) would be maintained during the 21 month project period. Ten additional full time DCM jobs would be maintained after renovation. Mechanical systems renovation on the Grey Side of the resource core facility is critical to maintain the animal research program at Georgetown University. Optimal ventilation and proper sanitation of equipment/facilities safeguard animal health and support the conduct of PHS and other extramural supported research. If these mechanical systems fail, the institution risks the loss of irreplaceable animal models, 57 funded research programs, AAALACi accreditation and USDA registration.

描述（由申请人提供）：比较医学部（DCM）是乔治城大学唯一的集中动物资源核心设施。该设施的使命是为涉及实验动物的研究提供最佳的饲养和兽医护理、专业技术支持和适当的监管监督。这座占地 50,740 平方英尺的设施积极支持 133 名研究人员的 218 项动物护理和使用协议。该建筑由两座翼楼组成——“灰色”侧和“蓝色”侧，分别建于 1986 年和 1995 年。五十七名调查员在灰色地带饲养动物并利用研究支持空间。 2006 年，大学启动了一项分 3 阶段、为期 5 年的计划，以更换 Gray Side 已有 23 年历史的机械系统。目前正在进行两个 NCRR G20 赠款项目，以完成前两个计划阶段，包括更换不运行的加湿器；老化的排气扇、笼式清洗设备和楼宇管理系统；以及专用笼清洗设施高压系统的升级。 该提案旨在通过更换 3 台空气处理机组 (AHU) 和相关机械支持设备来完成机构长期计划的第三阶段。要求更换“实物”设备，所有工作仅在机械空间（4,072 平方英尺）内进行。现有空气处理机组的冗余将允许分阶段更换，同时最大限度地减少对通风和正在进行的研究的干扰。该项目采用符合 LEED 标准的可持续设计原则。在 21 个月的项目期间，美国的就业岗位（15-23 FTE）将得到维持。改造后将保留 10 个额外的全职 DCM 工作岗位。 资源核心设施灰色面的机械系统改造对于维持乔治城大学的动物研究项目至关重要。设备/设施的最佳通风和适当卫生可保障动物健康并支持 PHS 和其他校外支持研究的开展。如果这些机械系统出现故障，该机构将面临失去不可替代的动物模型、57 个资助的研究项目、AAALACi 认证和 USDA 注册的风险。