Johns Hopkins O'Brien Center to Advance Kidney Health Equity

约翰霍普金斯奥布莱恩中心致力于促进肾脏健康公平

• 批准号: 10747703
• 负责人: DEIDRA CANDICE CREWS
• 金额: $ 85.78万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10747703
• 关键词: Address; Advisory Committees; Basic Science; Behavior Therapy; Biometry; Brain; Calibration; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communities; Consultations; Diet; Dietary Assessment; Discipline; Discrimination; Disparity; Disparity population; Education; Ensure; Equation; Ethnic Origin; Fostering; Gender; Germ-Free; Goals; Health; Health Food; Health Promotion; Housing; Incubators; Inequity; Infrastructure; Intervention; Intervention Studies; Joints; Kidney; Kidney Diseases; Laboratories; Lead; Mus; Nephrology; Periodicals; Phenotype; Population Heterogeneity; Prevention Research; Proteomics; Protocols documentation; Quality Control; Race; Recommendation; Research; Research Design; Research Personnel; Resource Development; Resources; Risk; Services; Sex Differences; Societies; Socioeconomic Status; Stress; Structural Racism; Students; System; Translations; Validation; biomedical resource; burden of illness; career; dietary; epidemiology study; experience; gut microbiota; health disparity; health equity; health inequalities; humanized mouse; innovation; marginalization; marginalized community; marginalized population; microbiome; novel; outreach; population health; pre-clinical; pre-clinical research; programs; social; social disparities; social health determinants; social stressor; socioeconomics; summer student; tool; translational scientist

OVERALL ABSTRACT Disparities in kidney health are profound; and for decades, have been documented for socially marginalized populations, yet little progress has been made to mitigate them. The overarching goal of the Johns Hopkins O’Brien Center to Advance Kidney Health Equity (JHOC) is to harness the collective expertise of basic, clinical and translational researchers at Johns Hopkins to serve as a national resource for investigators addressing the fundamental question of: what are the underlying mechanisms responsible for profound disparities in kidney health and how can they be mitigated? We will leverage the strengths and existing infrastructure of the Johns Hopkins Division of Nephrology, the Welch Center for Prevention, Epidemiology and Clinical Research and the Johns Hopkins Center for Health Equity. JHOC will include; 3 integrated cores (Administrative, Biomedical Resource and Resource Development); an Executive Committee; an Internal Advisory Committee, and a Community Advisory Board. Together, we will (1) provide an innovative portfolio of research services, resources, and tools for investigators to understand and ameliorate disparities in kidney disease; (2) develop new and refine existing resources as part of a dynamic incubator space for the conduct of basic and clinical research relevant to advancing kidney health equity; (3) transfer mature resources to the Biomedical Resource Core to be shared with the community; (4) plan and execute an annual Summer Student Enrichment Program which leverages a long-standing partnership with a Johns Hopkins program for students from socioeconomically under-resourced backgrounds; (5) foster the careers of early-stage investigators by promoting trans-disciplinary and cross-sector collaboration that will attract investigators from fields not traditionally involved in kidney health equity research; and (6) collaborate with the National Coordinating Center to prioritize external requests for resources and enhance national outreach. JHOC will support investigators conducting pre-clinical (basic), clinical or population health research addressing kidney health disparities, and will make recommendations to inform strategies, interventions, and approaches aimed at achieving kidney health equity.

全面的 抽象的 数十年来，社会弱势群体的肾脏健康状况存在巨大差异。 约翰·霍普金斯大学的总体目标是，在缓解这些问题方面几乎没有取得任何进展。 奥布莱恩促进肾脏健康公平中心 (JHOC) 旨在利用基础、临床的集体专业知识 约翰·霍普金斯大学的转化研究人员为研究人员提供国家资源 基本问题：造成肾脏巨大差异的根本机制是什么 我们将利用约翰斯的优势和现有基础设施来缓解这些问题？ 霍普金斯肾病科、韦尔奇预防、流行病学和临床研究中心以及 约翰·霍普金斯健康公平中心将包括 3 个综合核心（行政、生物医学）。 执行委员会；内部咨询委员会； 我们将共同 (1) 提供创新的研究服务组合， 为研究人员提供了解和改善肾脏疾病差异的资源和工具；(2) 开发 新建和完善现有资源，作为进行基础和临床的动态孵化器空间的一部分 与促进肾脏公平健康相关的研究；（3）将成熟资源转移到生物医学资源 与社区共享的核心内容；（4）规划并执行年度暑期学生强化计划 它利用与约翰·霍普金斯大学项目的长期合作伙伴关系，为来自以下国家的学生提供帮助： (5) 培养早期研究者的职业生涯 促进跨学科和跨部门的合作，这将吸引来自其他领域的研究人员 传统上参与肾脏健康公平研究；以及 (6) 与国家协调中心合作； 中心将优先考虑外部资源请求并加强国家外展工作。 研究人员进行针对肾脏健康的临床前（基础）、临床或人口健康研究 差异，并将提出建议，为旨在实现这一目标的战略、干预措施和方法提供信息 实现肾脏健康公平。