Development of a Tailored HIV Prevention Intervention for Young Men

为年轻男性制定量身定制的艾滋病毒预防干预措施

• 批准号: 9274460
• 负责人: Jose Arturo Bauermeister
• 金额: $ 17.08万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9274460
• 关键词: AIDS prevention; AIDS/HIV problem; Accounting; Address; Affect; Affective; Age; Anus; Attention; Behavior; Behavioral; Cognitive; Communities; Couples; Data; Decision Making; Development; Diffuse; Emotional; Equilibrium; Feedback; HIV; HIV Infections; HIV risk; HIV/STD; Health; Individual; Infection; Intervention; Learning; Mediation; Modality; Motivation; Multiple Partners; Online Systems; Phase; Planning Theory; Play; Preparation; Preventive Intervention; Procedures; Process; Randomized Controlled Trials; Relationship-Building; Reporting; Research; Risk; Risk Behaviors; Risk Reduction; Risk Reduction Behavior; Role; Safe Sex; Same-sex; Self Efficacy; Testing; Variant; Youth; base; behavior test; cognitive process; condoms; consistent condom use; design; expectation; experience; follow-up; ideation; insight; interest; iterative design; men who have sex with men; programs; sex risk; sexual risk taking; skills; therapy design; therapy development; usability; young man; young men who have sex with men

 DESCRIPTION (provided by applicant): A resurgence of new HIV/AIDS cases among young men who have sex with men (YMSM; ages 18-24) underscores the importance of developing culturally and developmentally informed HIV/AIDS programs for YMSM. We propose to develop and pilot test a tailored, web-based intervention called MEET-ME that focuses on delivering HIV/AIDS prevention messages based on single YMSMs' relationship expectations and partner- seeking behaviors. To maximize intervention appeal and appropriateness, we will convene a youth advisory board (YAB) to provide insight and feedback during the intervention development process. Using an iterative design and development process, we will develop tailored messages that align YMSM's relationship experiences and desires with HIV/AIDS prevention strategies. We will then design and develop the MEET-ME tailored online prevention intervention, as well as an attention-control non-tailored HIV/AIDS prevention (NTHP) comparison intervention. After developing both interventions, we will use usability testing procedures to collect preliminary data from 16 YMSM on the proposed intervention's design and acceptability. Recommended changes will be added to the intervention prior to launching a small pilot randomized controlled trial (RCT). The pilot RCT will compare MEET-ME (N=120) to NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary behavioral data to inform a subsequent application. Assessments will be collected at 30, 60, and 90 days follow-up. Specific Aims include: (1) To develop a tailored (MEET-ME) and non-tailored (NTHP) HIV/AIDS prevention intervention focused on addressing HIV/AIDS risk behaviors among single YMSM (ages 18-24); (2) To collect preliminary data on the feasibility, acceptability, and intervention content of the MEET-ME (N=16) in preparation for a small pilot RCT; and, (3) To implement a small pilot RCT of the refined MEET-ME (N=120) as compared to the NTHP (N=60) intervention, in order to evaluate its feasibility and acceptability and gather preliminary efficac results in reducing sexual risk behaviors.

 描述（由申请人提供）：男男性行为青年（YMSM；年龄 18-24 岁）中新的艾滋病毒/艾滋病病例的重新出现，强调了为 YMSM 制定文化和发展方面的艾滋病毒/艾滋病项目的重要性。开发并试点测试一种名为“MEET-ME”的基于网络的定制干预措施，重点是根据单身 YMSM 的关系期望和寻求伴侣的行为来传递艾滋病毒/艾滋病预防信息，以最大限度地提高干预措施的吸引力和适当性。我们将召集一个青年顾问委员会 (YAB)，在干预措施制定过程中提供见解和反馈，通过迭代设计和开发流程，我们将制定量身定制的信息，使 YMSM 的关系经验和愿望与艾滋病毒/艾滋病预防战略保持一致。然后设计和开发 MEET-ME 定制的在线预防干预措施，以及注意力控制非定制的艾滋病毒/艾滋病预防（NTHP）比较干预措施。开发这两种干预措施后，我们将使用可用性测试程序来收集初步数据。 从 16 YMSM 开始，将在启动小型试点随机对照试验 (RCT) 之前对干预措施的设计和可接受性进行建议的更改。试点 RCT 将比较 MEET-ME (N=120) 和 NTHP (N=120)。 60) 评估干预的可行性和可接受性，并收集初步行为数据，为后续应用提供信息。评估将在 30 天、60 天和 90 天的随访中收集。包括： (1) 制定量身定制 (MEET-ME) 和非定制 (NTHP) 艾滋病毒/艾滋病预防干预措施，重点解决单身 YMSM（18-24 岁）的艾滋病毒/艾滋病风险行为； (2) 收集初步信息；关于 MEET-ME (N=16) 的可行性、可接受性和干预内容的数据，以准备小型试点 RCT；以及 (3) 实施完善的 MEET-ME (N=120) 的小型试点 RCT；作为与NTHP（N=60）干预进行比较，评估其可行性和可接受性，并获得减少性危险行为的初步疗效结果。