Training Program in Translational Cardiovascular Science

转化心血管科学培训项目

• 批准号: 10270772
• 负责人: Lee Lochbaum Eckhardt
• 金额: $ 51.18万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-17 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270772
• 关键词: Cardiovascular system; Science; Training Programs

PROJECT SUMMARY/ABSTRACT This application seeks renewal for Years 21-25 of the Training Program in Translational Cardiovascular Science (TPTCS) within the School of Medicine and Public Health Cardiovascular Research Center (CVRC) at the University of Wisconsin-Madison. The CVRC is a campus-wide interdisciplinary research center with faculty and research members from 31 departments in seven schools and colleges, providing a rich environment targeting cardiovascular disease through basic research, clinical investigation, diagnosis and therapy, and public education. The TPTCS training program uniquely creates basic research training for postdoctoral MDs and PhDs (four positions) as well as predoctoral trainees (five positions) with the goal of training scientists who will be capable of thinking and working “from molecule to bedside.” The practical immediate objectives are to attract and train clinicians in basic research, and to attract and train graduate and postdoctoral (PhD) students in clinically motivated basic science. The TPTCS aims to appoint physicians as part of their resident and fellow training to half the postdoctoral positions. One of the long-standing strengths of the program emerging from annual program evaluation is its integration of training among predoctoral students, basic science postdoctoral trainees, and clinical fellows who work side-by-side in journal clubs, in seminar series, and at the bench in laboratories. This blending and sharing of different trainee perspectives is foundational to the goals of the program and creates esprit de corps. The 27 trainers of the TPTCS have been selected from members of the CVRC for the clinical relevance of their science in the focus areas (heart failure/regenerative medicine, arrhythmias/ion channel research, and atherosclerosis/vascular biology), their training records, and the overall robustness and activity of their peer-reviewed research programs. Training takes place at the University of Wisconsin-Madison and exploits the strong institutional support and environment for such training, as well as the established working relationships between clinical and basic science departments and faculty both within the School of Medicine and Public Health and the University at large. Trainers and trainees all participate in core activities that define the program as a cohesive entity. Several innovations are introduced in this renewal, including enhanced clinical integration for the basic science trainees and greater professional development opportunities to prepare all trainees for the next stages in their careers. Appointees to the program to date are extremely strong and program outcomes have been excellent. The scientists and physician-scientists trained in this translational cardiovascular science program are in unique positions to apply basic scientific knowledge to benefit patients with cardiovascular disease, the foremost cause of mortality among Americans.

项目概要/摘要 本申请寻求转化心血管培训计划第 21-25 年的更新 医学院和公共卫生心血管研究中心 (CVRC) 内的科学 (TPTCS) CVRC 是威斯康星大学麦迪逊分校的跨学科研究中心。 来自七所学校和学院 31 个系的教职人员和研究人员，提供了丰富的 通过基础研究、临床调查、诊断和治疗来针对心血管疾病的环境 TPTCS 培训项目独特地为患者提供了基础研究培训。 博士后医学博士和博士（四个职位）以及博士前培训生（五个职位），目标是 培养能够“从分子到临床”思考和工作的科学家。 近期目标是吸引和培训基础研究人群，并吸引和培训研究生和 TPTCS 旨在任命临床驱动的基础科学博士后 (PhD) 学生。 他们的住院医师和研究员培训的一部分占博士后职位的一半。 年度项目评估中出现的项目是对博士前学生的培训的整合， 基础科学博士后实习生和在期刊俱乐部并肩工作的临床研究员，在研讨会上 系列，以及在实验室的工作台上，这种不同学员观点的融合和分享是。 TPTCS 的 27 名培训师为实现该计划的目标奠定了基础，并培养了团队精神。 从 CVRC 成员中选出，因其科学在重点领域（心脏）的临床相关性 衰竭/再生医学、心律失常/离子通道研究和动脉粥样硬化/血管生物学），他们的 培训记录，以及经过同行评审的研究项目的整体稳健性和活动性。 会议在威斯康星大学麦迪逊分校举行，利用强大的机构支持和 此类培训的环境，以及临床和基础之间已建立的工作关系 医学与公共卫生学院和大学的科学部门和教员 培训师和受训者都参与核心活动，将计划定义为一个有凝聚力的实体。 此次更新引入了多项创新，包括加强基础科学的临床整合 学员和更多的专业发展机会，让所有学员为下一阶段的工作做好准备 迄今为止，该计划的被任命者都非常强大，并且计划成果也非常出色。 接受过这一转化心血管科学项目培训的科学家和医师科学家都在 运用基础科学知识造福心血管疾病患者的独特地位 美国人死亡的首要原因。