HPV and Cancer mHealth Prevention Education for HIV Positive Women Pilot Study

针对 HIV 阳性女性的 HPV 和癌症 mHealth 预防教育试点研究

• 批准号: 9322805
• 负责人: Lisa Tisdale Wigfall
• 金额: $ 14.22万
• 依托单位: TEXAS A&M UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-13 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9322805
• 关键词: AIDS prevention; AIDS/HIV problem; Academic Training; Acquired Immunodeficiency Syndrome; Active Learning; Address; Adherence; African American; Applications Grants; Appointment; Area; Awareness; Behavior; Belief; Cancer Biology; Cancer Burden; Cancer Control; Cancer Control Research; Chronic Disease; Clinic; Clinical; Clinical Immunology; Collaborations; Communication; Communication Research; Communities; Data; Detection; Development; Diagnosis; Dysplasia; Educational Intervention; Effectiveness; Enabling Factors; Environment; Epidemiology; Extramural Activities; Failure; Funding; Future; Goals; HIV; HIV Seropositivity; HIV/STD; Head and Neck Cancer; Health; Health Communication; Health Promotion and Education; Health Services Research; Health system; High-Risk Cancer; Homelessness; Human Papillomavirus; Human papilloma virus infection; Immune system; Incidence; Individual; International; Intervention; K-Series Research Career Programs; Knowledge; Life; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mediating; Mentors; Mentorship; Modeling; Needs Assessment; Oncogenic; Outcome; Peer Review; Pilot Projects; Population; Predisposing Factor; Prevention; Prevention education; Procedures; Process; Professional counselor; Provider; Publications; Recruitment Activity; Reinforcing Factor; Research; Research Activity; Research Assistant; Research Design; Research Personnel; Research Training; Resources; Risk; Risk Reduction; Rural; Safe Sex; Science; Screening for cancer; Services; Shelter facility; Social support; South Carolina; Technology; Testing; Training; Training Activity; Vulnerable Populations; Woman; Women' s Group; Work; anticancer research; base; cancer care; cancer epidemiology; cancer health disparity; cancer prevention; cancer risk; career; career development; cervical cancer prevention; community based participatory research; community partnership; cost effective; data management; diagnostic screening; evaluation/testing; experience; follow-up; health belief; health disparity; improved; innovation; mHealth; medically underserved; meetings; mid-career faculty; mobile computing; mortality; multilevel analysis; peer; post-doctoral training; prevent; professor; programs; public health relevance; research study; screening; skills; social; symposium; therapy development; tool; underserved minority

DESCRIPTION (provided by applicant): The candidate is a research assistant professor with academic training in health promotion, education, and behavior, as well as postdoctoral training in HIV/AIDS prevention, health disparities, and health services research. She also has data management expertise and clinical immunology experience. The candidate has completed two pilot studies that examined HPV infection and cervical cancer prevention knowledge, beliefs and screening behaviors among women living with HIV (WLH). The candidate is seeking additional training needed to develop and implement effective cancer health (including mHealth) communication and community navigation strategies to improve WLH's timely use of cancer screening, diagnostic and treatment services and procedures. The candidate's long-term goal is to obtain extramural research funding for her independent research program focusing on the prevention and control of HPV-mediated cancers among WLH over the next 5-10 years. Promotion to associate professor (tenure- or research-track) is an intermediate goal that the candidate is striving to attain within the next five years. A combination of formal didactic trainig and experiential learning opportunities will be used to acquire cancer prevention and control research skills in the following areas: cancer health (including mHealth) communication, cancer epidemiology, HPV-mediated cancer biology, community navigation, advanced epidemiological research skills (e.g., social epidemiology, n- of-1 research study designs, and, multilevel modeling). The candidate will use the cancer prevention and control research and health communication knowledge and skills acquired through the proposed career development award to conduct formative research needed to inform intervention development in which she will examine cancer health information seeking and sharing among WLH as well as their non-clinical HIV service providers (e.g., HIV/STI risk reduction counselors). Non-clinical HIV service providers will be included because, in addition to the fact that these individuals are already promoting safe sexual practices among WLH, they are also able to reach marginalized groups of WLH such as those who are homeless. This includes sheltered and unsheltered homeless WLH. The candidate's mentors and co-mentors have scientific expertise and community-based participatory research experience that will increase the likelihood of the proposed specific aims being successfully completed. The candidate will first examine HPV-mediated cancer prevention knowledge, beliefs and behaviors, as well as cancer health communication seeking and sharing behaviors (including the use of technology to find health information) (Aim 1). These formative research data will then be used to inform the development (Aim 2) and subsequent pilot testing and evaluation (Aim 3) of an HPV- mediated cancer prevention mHealth education intervention aimed at training WLH who already serve as peer leaders and non-clinical HIV service providers to use mHealth tools and community navigation strategies to disseminate HPV-mediated cancer prevention education. As community navigators, these individuals will use cancer health (including mHealth) communication and community navigation strategies to increase awareness about HPV-mediated cancer risk. This will include promoting cancer risk reducing behaviors such as safe sexual practices and the timely use of recommended cancer screening, diagnostic, and treatment services and procedures). Recall and reminder messages will be sent for screening and follow-up cancer care appointments. User-defined social support messages will also be sent to WLH who may be encountering access to cancer care barriers. The candidate will disseminate the scientific research findings to local, regional, national, and international audiences via presentations that she will give at scientific conferences and annual meetings as well as peer-reviewed publications that she will produce. Most relevant to the candidate's long-term goal of attaining research independence is increasing her number of peer-reviewed publications from her current publication rate of approximately three per year to four or more produced annually by the end of the 5-year training period and the submission of at least one grant proposal (e.g., R01-level funding) by the end of the 5-year training period. The proposed career development/training and research activities will enable the candidate to realize her long-term career goal of becoming an independent cancer researcher with expertise in using cancer health communication, community navigation, and mHealth technologies to address health system failures encountered by vulnerable, medically-underserved WLH along the cancer care continuum. Continued mentoring and opportunities for team science research collaborations will facilitate the candidate's successful progression to being an independent cancer researcher. WLH and non-clinical HIV service providers will be recruited from Ryan White funded clinics and AIDS-service organizations located in urban and rural geographical areas of South Carolina that represent a microcosm of disparities in HIV/AIDS, cancer, and other chronic illness that disproportionately burden medically underserved minority populations. Addressing health system failures that occur along the cancer care continuum that result in missed opportunities to prevent, detect, diagnose and treat HPV-mediated cancers will help to reduce the burden of cancer incidence and mortality among this high cancer risk, vulnerable group of WLH. The proposed HPV-mediated cancer mHealth prevention education intervention will be conducted in a community-based setting and builds upon an existing academic-community partnership between the candidate and a local AIDS-service organization. The candidate has a supportive, resource-intensive scientific environment for her cancer research training.

描述（由申请人提供）：候选人是一名研究助理教授，对健康促进，教育和行为的学术培训以及艾滋病毒/艾滋病预防，健康差异和卫生服务研究的博士后培训。她还拥有数据管理专业知识和临床免疫学经验。候选人已经完成了两项试点研究，研究了HPV感染和宫颈癌的预防知识，信念和筛查行为（WLH）。候选人正在寻求开发和实施有效的癌症健康（包括MHealth）的沟通和社区导航策略所需的额外培训，以改善WLH及时使用癌症筛查，诊断和治疗服务和程序。候选人的长期目标是为她的独立研究计划获得校外研究资金，重点是在未来5 - 10年内对HPV介导的癌症的预防和控制。晋升为副教授（任期或研究轨道）是候选人在未来五年内努力实现的中间目标。形式教学教学和体验式学习机会的结合将用于在以下领域获得癌症预防和控制研究技能：癌症健康（包括MHealth）沟通，癌症流行病学，HPV介导的癌症生物学，社区导航，高级流行病学研究技能（例如，社会流行病学，n- of-1研究研究设计，以及多重级别的模型）。候选人将使用通过拟议的职业发展奖获得的癌症预防和控制研究和健康沟通知识和技能，以进行干预开发所需的形成性研究，以便她研究癌症健康信息在WLH及其非临床HIV服务提供者之间的寻求和共享（例如，HIV/STI降低风险降低咨询师）。将包括非临床艾滋病毒服务提供商，因为除了这些人已经在WLH中促进安全的性行为之外，他们还能够接触到边缘化的WLH群体，例如那些无家可归的人。这包括庇护和无家可归的无家可归者。候选人的导师和联席会员拥有科学专业知识和基于社区的参与研究经验，这将增加所提出的特定目标成功完成的可能性。候选人将首先检查HPV介导的癌症预防知识，信念和行为，以及癌症健康沟通寻求和共享行为（包括使用技术来找到健康信息）（AIM 1）。然后，这些形成性研究数据将用于告知开发（AIM 2），并随后对HPV介导的癌症预防MHealth教育干预措施的试点测试和评估（AIM 3），旨在培训已经用作同行领导者和非临床HIV服务提供者的WLH，并使用MHPV癌症癌症癌症的癌症预防。作为社区导航员，这些人将使用癌症健康（包括MHealth）的沟通和社区导航策略来提高人们对HPV介导的癌症风险的认识。这将包括促进癌症风险降低行为，例如安全性实践，以及及时使用建议的癌症筛查，诊断和治疗服务和程序）。召回和提醒消息将发送筛查和后续癌症护理约会。用户定义的社会支持消息也将发送给可能正在遇到癌症护理障碍的WLH。候选人将通过演讲将科学研究的发现传播给本地，地区，国家和国际观众，她将在科学会议和年度会议上以及她将制作的同行评审出版物中提供。与候选人达到研究独立性的长期目标最相关的是，她的同行评审出版物的数量从她的当前出版率每年约三年的出版率增加到5年培训期结束时每年生产的四个或四个以上，并且在5年培训期结束时至少提交了一项赠款提案（例如R01级资助）。拟议的职业发展/培训和研究活动将使候选人能够实现她的长期职业目标，即在使用癌症健康传播，社区导航和MHealth技术方面成为独立的癌症研究员，以解决沿着癌症护理沿癌症护理的易受伤害，医疗服务的WLH遇到的卫生系统失败。持续的指导和团队科学研究合作的机会将促进候选人成为独立癌症研究员的成功发展。 WLH和非临床HIV服务提供商将从位于南卡罗来纳州城市和农村地理区域的Ryan White Funded Clinics和AIDS服务组织中招募，这些组织代表了艾滋病毒/艾滋病，癌症和其他慢性疾病的缩影，这些疾病是医学上不成比例的少数少数少数少数疾病。解决沿癌症护理连续体发生的卫生系统失败，导致缺失的机会预防，检测，诊断和治疗HPV介导的癌症将有助于减轻这种高癌症风险的癌症发病率和死亡率的负担，这是WLH脆弱的群体。拟议的HPV介导的癌症预防教育干预措施将在基于社区的环境中进行，并建立在候选人与当地艾滋病服务组织之间现有的学术社区合作伙伴关系的基础上。候选人为她的癌症研究培训提供了支持，资源密集的科学环境。