Core C: Research Support Core: Bioinformatics and Molecular Modeling

核心 C：研究支持 核心：生物信息学和分子建模

• 批准号: 9043071
• 负责人: STEFANO MONTI
• 金额: $ 18.54万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9043071
• 关键词: Address; Bioinformatics; Biological Assay; Chemistry; Cods; Collaborations; Communication; Communication Research; Communities; Computer software; Data; Decision Making; Development; Environmental Health; Federal Government; Goals; Government Agencies; Hazardous Waste; Hazardous Waste Sites; Health; Individual; Information Dissemination; Instruction; Knowledge; Life; Massachusetts; Methods; Modeling; Molecular Models; National Institute of Environmental Health Sciences; New England; Outcomes Research; Productivity; Public Health; Public Sector; Reagent; Regulation; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Rhode Island; Risk Assessment; Signal Recognition Particle; State Government; Superfund; Techniques; Technology; Technology Transfer; Toxicology; Training; Translational Research; Water; Work; base; developmental toxicity; environmental chemical; improved; meetings; molecular modeling; programs; receptor; reproductive; reproductive toxicity; superfund chemical; tool; willingness

PROJECT SUMMARY (See Instructions): The purpose of the Research Translation Core is to make research outcomes available to governmental organizations responsible for protecting the health of local communities, to the scientific community in general, and to other SRPs in particular. This is in addition to organizations engaged with the BU SRP through the Community Engagement Core. The principal goal is to provide knowledge of exposure and health effects useful in risk assessment needed for consequential decision-making. This proposal builds on our previous work and includes new partners who can use the SRP and Project results for assessment, regulation and reduction of contaminants found at hazardous waste sites. Specific Aim 1: Coordinate communication of research within BU SRP, in New England, and the larger NIEHS SRP community to improve application of findings, provide access to data, consolidate resources and increase productivity and collaboration. Specific Aim 2: Develop and. maintain partnerships with governmental environmental and public health agencies and provide them with data and expertise that might improve risk assessment-based decisions, particularly with respect to developmental and reproductive effects of environmental chemicals. Specific Aim 3: Effect technology transfer by identifying potential end-users of technologies, assays and resources developed by BU SRP projects and facilitate their application. Specific Aim 4: Pursue, initiate and implement Center-specific research translation activities (i.e., emanating from the BU SRP), working with the Community Engagement and Training Cores to have a broader impact.

项目摘要（请参阅说明）： 研究翻译核心的目的是使负责保护当地社区健康，一般科学界以及尤其是其他SRP的政府组织可获得研究成果。这是通过社区参与核心与BU SRP互动的组织的补充。主要目标是提供有关暴露和健康效应的知识，可用于结果决策所需的风险评估。该提案以我们以前的工作为基础，包括可以使用SRP和项目结果的新合作伙伴进行评估，法规和减少危险废物站点发现的污染物。 具体目标1：协调BU SRP，新英格兰和更大的NIEHS SRP社区的研究的沟通，以改善发现的应用，提供数据访问，巩固资源并提高生产力和协作。 特定目标2：开发和。保持与政府环境和公共卫生机构的合作伙伴关系，并为他们提供数据和专业知识，以改善基于风险评估的决策，尤其是在环境化学品的发展和生殖影响方面。 特定目标3：通过确定BU SRP项目开发的技术，测定和资源的潜在最终用户的影响技术转移并促进其应用。 特定目的4：追求，启动和实施特定于中心的研究翻译活动（即，从BU SRP发出），与社区参与和培训核心合作，产生更大的影响。