Comprehensive Mechanisms in Reproductive Sciences

生殖科学综合机制

• 批准号: 10615873
• 负责人: STEPHANIE A. PANGAS
• 金额: $ 41.72万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615873
• 关键词: Reproductive Sciences

Project Summary and Abstract Our program goal is to train talented young scientists for research-intensive and research-related careers in reproductive biology. Baylor College of Medicine is a long-standing leader in reproductive biology research. Predoctoral and postdoctoral trainees receive mentored training in biomedical research and career development to obtain skills necessary for a variety of career paths. The predoctoral program combines state-of-the-art training in premier reproductive biology laboratories along with didactic learning. Postdoctoral fellows attend courses and seminars alongside their research training. Both will have structured committees for research and career advising that include a formal oral presentation. Trainee mentorship is guided by program-specific Individual Development Plans (IDP), developed in conjunction with the mentor and a core executive committee member. Activities to enhance skills in teaching, clinical/translational work, and entrepreneurship, is offered by BCM and neighboring collaborative institutions within the world's largest medical center. Program specific activities include a mentored journal club, an annual mini-symposium, research advisory committees, NRMN modules for mentor-mentee training, formal critiques of oral communications, assistance with development of fellowship applications, and individual career planning programs. These programs are supplemented with training in responsible conduct of research and a novel “ethics in reproductive health learning unit” specifically designed for this proposal. The 13 faculty members have been selected for contemporary research interests in reproductive biology and are currently supported by over $14 million in funding with $6 million in NICHD funding alone (43% of total PI funding). Their research areas fall squarely within the mission of NICHD, and includes studies of key reproductive biology proteins, normal and pathophysiology of male and female reproductive tissues, genetic and environmental factors that affect fertility, and translational research (male contraceptive development and developmental origins of adult disease). The training faculty use cutting edge approaches to study reproductive processes using genetic models, patient samples, in vitro models, and clinical data. Our program is designed for three predoctoral students and four postdoctoral fellows. We plan to support trainees for two years with an option to compete for a third year. Due to the long-standing reproductive biology research program at BCM and an active national recruiting strategy, we currently have a strong applicant pool in our training labs from which to select trainees, including pre- and postdoctoral trainees from UR groups. In total, our program provides necessary skills and experience to prepare the next generation of scientists for successful and diverse careers in reproductive biology.

项目概要和摘要 我们的计划目标是培养有才华的年轻科学家从事研究密集型和研究相关的职业 贝勒医学院是生殖生物学研究领域的长期领导者。 博士前和博士后学员接受生物医学研究和职业发展方面的指导培训 获得各种职业道路所需的技能。博士前课程结合了最先进的培训。 在一流的生殖生物学实验室与博士后研究员一起参加课程和学习。 研讨会以及研究培训都将成立研究和职业咨询委员会。 其中包括正式的口头陈述，受训者指导以特定计划的个人发展为指导。 与导师和核心执行委员会成员共同制定的计划（IDP）。 提高教学、临床/翻译工作和创业技能，由 BCM 和邻近的机构提供 世界上最大的医疗中心内的合作机构的具体活动包括指导。 期刊俱乐部、年度小型研讨会、研究咨询委员会、导师-受训者 NRMN 模块 培训、对口头交流的正式批评、协助开发奖学金申请，以及 这些计划还辅以负责任的行为培训。 研究和专门为此提案设计的新颖的“生殖健康伦理学习单元”13。 教职人员已被选拔从事生殖生物学的当代研究兴趣，并且是 目前获得超过 1400 万美元的资金支持，其中仅 NICHD 资金就有 600 万美元（占 PI 总额的 43%） 他们的研究领域完全属于 NICHD 的使命，包括关键生殖研究。 生物学蛋白质、男性和女性生殖组织的正常和病理生理学、遗传和 影响生育力的环境因素和转化研究（男性避孕药的开发和 成人疾病的发育起源）。培训教师使用尖端方法来研究生殖。 我们的程序专为使用遗传模型、患者样本、体外模型和临床数据而设计。 我们计划为实习生提供为期两年的支持，并有一个选择。 由于 BCM 的长期生殖生物学研究项目和 积极的国家招聘战略，目前我们的培训实验室拥有强大的申请人库，可以从 选择受训者，包括来自 UR 团队的博士前和博士后受训者。 为下一代科学家成功和多样化职业做好准备的必要技能和经验 在生殖生物学中。