Building Bridges, Breaking Barriers: An Academic-Community Partnership to Address Disparities in Uterine Fibroids

搭建桥梁，打破障碍：学术界合作解决子宫肌瘤的差异

• 批准号: 9113359
• 负责人: Erica E Marsh
• 金额: $ 3万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-20 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9113359
• 关键词: Academic Medical Centers; Accounting; Address; Affect; African American; Age; Anemia; Area; Attitude; Behavior; Benign; Caucasians; Clinical; Communities; Congresses; Data; Disease; Education; Epidemiologic Studies; Erythrocytes; Fibroid Tumor; Focus Groups; Future; Goals; Grant; Health; Health education; Hemorrhage; Hispanics; Housing; Human Subject Research; Hysterectomy; Incidence; Individual; Infertility; International; Interview; Knowledge; Latina; Lead; Learning; Menorrhagia; Menstruation; Methods; Natural History; Output; Patients; Pelvic Pain; Pregnancy loss; Prevalence; Preventive screening; Primary Health Care; Recurrence; Research; Research Personnel; Risk; Role; Smooth Muscle Tumor; Surveys; United States; United States National Institutes of Health; Universities; Uterine Fibroids; Uterine Neoplasms; Uterus; Woman; Women' s Group; Work; Writing; aged; clinically significant; community based participatory research; community organizations; community partnership; cost; design; effective intervention; empowered; health disparity; innovation; insight; interest; racial and ethnic disparities; reproductive; social; study population; tertiary care

 DESCRIPTION (provided by applicant): An Academic-Community Partnership to Address Disparities in Uterine Fibroids seeks to eradicate the significant health disparities in uterine fibroids amongst African- American women (AAW) and Latinas. Uterine leiomyomas or "fibroids" are well-defined, benign smooth muscle tumors of the uterus. Fibroids are present in 30%-50% of reproductive-age women and have an estimated cumulative incidence of 70% by age 50 years. Fibroids are associated with menorrhagia, anemia, infertility, pelvic pain, and recurrent pregnancy loss, and are the leading cause of hysterectomy in the United States. Recent analyses estimate the cost of fibroids in the U.S. to be as high as $34 billion annually. We know that fibroids disproportionately affect AAW, with epidemiological studies showing cumulative incidence approaching 90% by the age of 50 years. While there are fewer data on Latinas, the available studies show an increased prevalence in Latinas versus Caucasian women as well. The overall objective of this proposal is to facilitate a partnership between community organizations and stakeholders with ties to AAW and Latinas and an academic medical center that will be empowered to creatively and organically study ways to address health disparities in uterine fibroids using a community-based participatory research (CBPR) approach. The results of this work will be clinically significant, as we currently have limited data on the current challenges and most effective interventions to reduce the burden of uterine fibroids in women who are most affected-AAW and Latinas. Our proposal is innovative in that it proposes initially community-engaged and ultimately CBPR approaches to create a community-driven, and therefore highly relevant, agenda for addressing uterine fibroids. To our knowledge, this has not been attempted to date. We propose the following specific aims to be pursued over a three-year grant period: For Aim 1, we will establish a community-academic partnership that will develop the capacity to conduct CBPR on health disparities in uterine fibroids. In Aim 2, we will identify the communities' knowledge of and areas of interests regarding uterine fibroids and related health disparities. Aim 3 will focus on the provision of health education and partnership information to community stakeholders on both uterine fibroids and health disparities and will provide education for academic stakeholders on appropriate community engagement. In Aim 4, we will develop a collaborative agenda that will be designed to sustain the partnership as well as identify, quantify, and ultimately reduce health disparities in uterine fibroids via CBPR research. The Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research called on researchers to diversify study populations of fibroid patients. The output from the proposed partnership will provide initial insight into the factors that promote uterine fibroid health disparities amongst African-American and Hispanic women and set an agenda for future CBPR to address these factors.

 描述（由适用提供）：解决子宫肌瘤差异的学术社区伙伴关系，旨在旨在放射非洲裔美国妇女（AAW）和拉丁美洲人的子宫肌瘤的重大健康差异。子宫平滑肌瘤或“肌瘤”是定义明确的子宫平滑肌肿瘤。肌瘤存在于30％-50％的生殖年龄妇女中，估计到50岁的累积事件为70％。肌瘤与月经，贫血，不育症，骨盆疼痛和复发性妊娠丧失有关，是美国子宫切除术的主要原因。最近的分析估计，美国肌瘤的成本每年高达340亿美元。我们知道，肌瘤对AAW的影响不成比例，流行病学研究表明累积事件到50岁时接近90％。尽管在拉丁裔方面的数据较少，但可用的研究表明，拉丁裔与高加索妇女的患病率也增加。该提案的总体目的是在社区组织和与AAW和拉丁裔有联系的利益相关者之间建立合作伙伴关系，以及一个学术医疗中心，该中心将有权使用基于社区的参与研究（CBPR）方法来创造性地研究解决子宫纤维中的健康分布的方法。这项工作的结果将在临床上具有重要意义，因为我们目前对当前挑战和最有效的干预措施的数据有限，以减少受影响最大的AAW和拉丁裔女性的子宫纤维燃烧。我们的建议具有创新性，因为它最初由社区参与的提案，并最终提出了CBPR的方法，以创建社区驱动的，因此高度相关的议程，以解决子宫纤维。据我们所知，这尚未尝试约会。我们提出以下具体目标，要在三年的赠款期内追求：对于AIM 1，我们将建立一个社区学术伙伴关系，该伙伴关系将发展有能力在子宫纤维中进行健康分配的能力。在AIM 2中，我们将确定社区对子宫纤维和相关健康分配的兴趣领域的知识。 AIM 3将重点介绍向社区利益相关者提供有关子宫纤维和健康分配的社区利益相关者的提供信息，并将为学术利益相关者提供有关适当社区参与的教育。在AIM 4中，我们将开发一个合作的Agerda，旨在通过CBPR研究来维持合作伙伴关系，并识别，量化和最终减少子宫纤维中的健康分布。国际卫生研究院第三次国际卫生研究院的诉讼程序呼吁研究人员多样化肌瘤患者的研究人群。拟议合作伙伴关系的产出将提供对促进非裔美国人和西班牙裔妇女子宫肌瘤健康差异的因素的初步见解，并为未来的CBPR建立了一个解决这些因素的AGERNDA。

项目成果

Hearing the Silenced Voices of Underserved Women: The Role of Qualitative Research in Gynecologic and Reproductive Care.

• DOI: 10.1016/j.ogc.2016.11.005
• 发表时间: 2017-03
• 期刊: Obstetrics and gynecology clinics of North America
• 影响因子: 3.2
• 作者: Lawson AK;Marsh EE
• 通讯作者: Marsh EE