The Administrative Core

行政核心

• 批准号: 10612949
• 负责人: Robert F. Schwabe
• 金额: $ 24.62万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-30 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10612949
• 关键词: Administrative Efficiency; Administrator; Adult; Basic Science; Bioinformatics; Biology; Caring; Cell Culture Techniques; Cells; Childhood; Clinical; Clinical Research; Collaborations; Communication; Communities; Community Outreach; Dedications; Digestive System Disorders; Disease; Doctor of Philosophy; Education; Educational Activities; Educational workshop; Effectiveness; Ensure; Environment; Epithelial Cells; Epithelium; Evaluation; Evolution; Expenditure; Feedback; Fees; Fostering; Funding; Future; Grant; Growth; Health; Homeostasis; Image; Inflammation; Institution; Leadership; Link; Liver diseases; Longevity; Mentors; Mentorship; Metabolism; Mission; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Natural regeneration; Neoplasms; Organ; Organoids; Productivity; Publications; Recording of previous events; Research; Research Personnel; Research Support; Resources; Schools; Science; Scientist; Services; Structure; Surveys; Technology; Training; Translational Research; Universities; Vision; Work; base; bioimaging; biomedical resource; career development; community engagement; empowerment; equity, diversity, and inclusion; experience; innovation; interest; member; multidisciplinary; new technology; next generation; operation; programs; research and development; single cell analysis; social media; success; web site

SUMMARY The inception of the Columbia University Digestive and Disease Research Center (CU-DLDRC) in 2019 has its foundational roots over the past 15 years through the resounding growth of basic, translational and clinical research. The CU-DLDRC reflects the enthusiasm, collaborations, productivity and success of its members as well as the long-term institutional support of digestive disease research at Columbia University. The CU-DLDRC comprises an interactive group of 49 highly productive members (30 full and 19 associate), united by their strive for excellence in adult and pediatric digestive disease research and care. Since the CU-DLDRC’s inception, the Administrative Core (AC) has enhanced the collaborative research culture through the following endeavors: (i) Fostering interdisciplinary networks and team science, and collaborations between basic and clinical researchers; (ii) promoting education, training, mentorship and diversity, equity and inclusion (DEI); and (iii) supporting new investigators. The CU-DLDRC’ central research theme “Epithelial Cells and their Interactions in Digestive Homeostasis and Disease” encompasses two interrelated subthemes with major impact on digestive health: “Epithelial Homeostasis, Metabolism and Regeneration” (Subtheme 1) and “Epithelial Interactions in Inflammation and Preneoplasia” (Subtheme 2). Four Biomedical Cores provide access to cutting-edge technologies and facilities: Clinical Research and Biospecimen; Organoid and Cell Culture; Bioimaging; and Bioinformatics and Single Cell Analysis. The CU-DLDRC includes active Pilot and Feasibility (P/F) and Enrichment (EP) Programs, empowering the next generation of scientists and promoting education and intellectual exchange. The AC, as central component of the CU-DLDRC, will contribute to the collation and implementation of its mission, activities and success via optimal organization of the research base; fiscal management; coordination, evaluation and continuous evolution of its components; and communication with oversight committees, the NIDDK and other DDRCCs. The AC is directed by experienced leaders with complementary expertise: Robert Schwabe, MD, PhD (Director); Timothy Wang, MD and Kara Margolis, MD (Associate Directors), supported by AC administrator Seetha Srinivasan, PhD. The AC will promote the mission and success of the CU-DLDRC through these Specific Aims: To provide governance through efficient administration, budgetary oversight, scientific leadership and interactions with oversight committees (Aim 1). To ensure state-of-the-art services, efficient operation and cross-core collaboration by the Biomedical Cores (Aim 2). To promote the next generation of scientists and monitor their success via the P/F Program (Aim 3). To foster a fertile environment and intellectual exchange through seminars and retreats, and to promote DEI via the EP (Aim 4). To highlight the CU-DLDRC, its cores, educational activities and accomplishments on our website (Aim 5). Successful realization of these Aims will contribute to the effectiveness and success of the CU-DLDRC.

概括 哥伦比亚大学消化与疾病研究中心（CU-DLDRC）于2019年成立， 过去 15 年，通过基础、转化和临床领域的迅猛发展，奠定了基础 CU-DLDRC 反映了其成员的热情、协作、生产力和成功。 以及哥伦比亚大学消化疾病研究中心的长期机构支持。 由 49 名高效成员（30 名正式成员和 19 名准成员）组成的互动小组组成，他们因努力而团结在一起 自 CU-DLDRC 成立以来，表彰其在成人和儿科消化疾病研究和护理方面的卓越表现。 行政核心（AC）通过以下努力增强了协作研究文化：（i） 促进跨学科网络和团队科学以及基础和临床之间的合作 研究人员；(ii) 促进教育、培训、指导和多样性、公平和包容性 (DEI)； 支持新的研究人员。 CU-DLDRC 的中心研究主题“上皮细胞及其相互作用”。 消化稳态和疾病”包含两个相互关联的子主题，对消化产生重大影响 健康：“上皮稳态、代谢和再生”（子主题 1）和“上皮细胞相互作用” 炎症和肿瘤前期”（子主题 2）。四个生物医学核心提供了接触尖端技术的机会。 技术和设施：临床研究和生物样本；生物成像； 生物信息学和单细胞分析包括主动试点和可行性 (P/F) 和 浓缩（EP）计划，赋予下一代科学家权力并促进教育和 AC 作为 CU-DLDRC 的核心组成部分，将为整理和交流做出贡献。 通过研究基地的财政组织，实现其使命、活动和成功； 管理；其组成部分的协调、评估和持续发展； 监督委员会、NIDDK 和其他 DDRCC 均由经验丰富的领导者领导。 补充专业知识：Robert Schwabe，医学博士、博士（主任）；Timothy Wang，医学博士和 Kara Margolis，医学博士； （副主任）在 AC 管理员 Seetha Srinivasan 博士的支持下 AC 将推动这一使命。 CU-DLDRC 通过以下具体目标取得成功： 通过有效的治理提供治理 管理、预算监督、科学领导以及与监督委员会的互动（目标 1）。 确保生物医学核心提供最先进的服务、高效运营和跨核心协作（目标 2). 通过 P/F 计划促进下一代科学家并监督他们的成功（目标 3）。 通过研讨会和务虚会创造肥沃的环境和知识交流，并通过 EP 推广 DEI （目标 4）在我们的网站上突出 CU-DLDRC、其核心、教育活动和成就（目标）。 5). 这些目标的成功实现将有助于 CU-DLDRC 的有效性和成功。