WORKSHOP ON UNDERSTANDING PATHWAYS TO SUCCESSFUL AGING: BEHAVIORAL AND SOCIAL FACTORS RELATED TO ALZHEIMER'S DISEASE

了解成功老龄化之路研讨会：与阿尔茨海默病相关的行为和社会因素

• 批准号: 9368916
• 负责人: DAVID WESTBROOK
• 金额: $ 15万
• 依托单位: NATIONAL ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-30 至 2017-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9368916
• 关键词: Address; Affect; Age-associated memory impairment; Aging; Alzheimer disease prevention; Alzheimer' s Disease; Alzheimer' s disease risk; Behavioral; Biological; Body Weight decreased; Cognitive; Diet Modification; Educational workshop; Elderly; Etiology; Exercise; Health; Impaired cognition; Incidence; Intervention; Life Style; Link; Neurotic Disorders; Pathway interactions; Personality; Predisposition; Prevention; Prevention strategy; Process; Research; Risk Factors; Role; Stress; Suggestion; Testing; behavioral/social science; evidence base; follow-up; implementation research; interest; normal aging; prevent; social

This proposed workshop also aims to address NIA’s objectives in the social and behavioral sciences that are consistent with strategies in the National Alzheimer’s Plan, including to expand research aimed at prevention, and is relevant to the Alzheimer’s Disease Research Implementation Milestones related to non-pharmacological interventions. Towards this end, BSR is particularly interested in understanding how potentially modifiable behavioral and social risk factors affect later life in cognitive status and Alzheimer’s disease (AD). Building on a strong evidence base linking a range of behavioral and social factors to cognitive health, several NIA-supported efforts are already underway to test whether social engagement, cognitive stimulation, dietary modification and weight reduction, exercise, artistic and creative activities, and stress reduction can prevent or remediate normal age-related cognitive decline. There is now also growing interest in understanding the role of behavioral and social processes, whether direct or via interactions with biological susceptibilities, in the etiology of AD and, in the longer term, assessing their potential as targets for AD prevention.

拟议的研讨会还旨在解决 NIA 在社会和行为科学方面的目标，这些目标与国家阿尔茨海默病计划中的战略一致，包括扩大旨在预防的研究，并与与非药物干预相关的阿尔茨海默病研究实施里程碑相关为此，BSR 特别有兴趣了解潜在可改变的行为和社会风险因素如何影响晚年的认知状态和阿尔茨海默病 (AD)，建立在将一系列行为和社会因素与认知联系起来的强有力的证据基础上。在健康方面，NIA 支持的几项工作已经在进行中，以测试社交参与、认知刺激、饮食调整和减肥、锻炼、艺术和创意活动以及减轻压力是否可以预防或补救与年龄相关的正常认知衰退。人们越来越有兴趣了解行为和社会过程（无论是直接的还是通过与生物易感性的相互作用）在 AD 病因学中的作用，并从长远来看，评估其作为 AD 预防目标的潜力。