2023 Nitric Oxide GRC and GRS

2023 一氧化氮 GRC 和 GRS

基本信息

批准号：
10608028
负责人：
Andrew J Gow
金额：
$ 1.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-01 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10608028
关键词：
Address Air Pollutants Alzheimer&apos s Disease Asthma Athletic Award Bacteria Basic Science Biochemistry Blood Vessels Budgets COVID-19 pandemic COVID-19 patient COVID-19 pneumonia California Carcinogens Cardiopulmonary Cardiovascular Diseases Cardiovascular system Chemistry Collaborations Communities Complex Consumption Data Detection Development Diabetes Mellitus Disabled Persons Discipline Disease Disease Resistance Dose Endothelium-Dependent Relaxing Factors Environment Enzymes Explosion Failure Fostering Functional disorder Funding Gender Generations Goals Health Health Status Hemoglobin Human Human Biology Human body Hypertension Inflammation International Life Lung Lung diseases Mission Molecular Nature Nitric Oxide Nitric Oxide Synthase Nitrous Oxide Nobel Prize Oral Organism Oxides Participant Pathology Patients Performance Pharmacology and Toxicology Physicians Physiological Physiology Play Postdoctoral Fellow Preparation Production Reaction Recording of previous events Relaxation Request for Proposals Research Research Personnel Role Running Science Scientist Signal Pathway Signal Transduction Signaling Molecule Source Structure System Therapeutic Therapeutic Intervention Time Training Translational Research United States National Institutes of Health Universities Vascular System Work body system design ethnic minority experience graduate student human disease improved inhaled nitric oxide insight interest meetings member neonatal pulmonary hypertension next generation novel novel therapeutics parity posters prevent professor programs racial minority respiratory health skills supportive environment symposium synergism

项目摘要

PROJECT SUMMARY This proposal requests partial support for a meeting on the “Molecular Mechanisms of Nitric Oxide Signaling in Health and Disease” as a Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) to be held in Ventura California from February 12th -17th 2023. The broad and long-term goal of this conference is to bring together the world's leading researchers in this field to foster cross-disciplinary discussions and collaborations. The meeting is designed to enhance our understanding of Nitric Oxide as a regulator of physiological function and as such an important target for control in both health and disease. In particular, we are interested in emphasizing how restoring appropriate Nitric Oxide signaling can alleviate diseases as varied as diabetes, hypertension, asthma, and COVID-19 related pneumonia. The 2023 conference will include a GRS for trainees held immediately prior to and in conjunction with the GRC. The specific aims of this meeting will be to convene over 35 leading experts who will present unpublished data and insights within the field of Nitric Oxide research. The GRC program will be structured into 9 sessions that comprehensively cover the field with sessions focused on cardiovascular performance, molecular mechanisms of signaling, Nitric Oxide generation and detection, and the role of Nitric Oxide in respiratory health. Both basic and translational research will be highlighted, with a major emphasis on physiological signaling and disruptions of this system that can be targeted to improve human health. Afternoon poster sessions will permit all participants to contribute to these topics with the most meritorious abstracts chosen by the conference Chair and Vice-Chair for oral presentations. Every effort will be made to encourage participation by graduate students and postdoctoral fellows in the GRC. In addition, the GRS will be specifically aimed at trainees, allowing them to present their research and interact in a relaxing and extra supportive environment. Every effort will be made to promote gender parity and include racial/ethnic minorities and persons with disabilities. The significance of this application lies in the much needed forum provided by the GRC and GRS to bring together and synergize the members of an international research community working on Nitric Oxide. Nitric Oxide research is unique in that it brings together chemists, environmental scientists, pulmonary and cardiovascular physicians. The Gordon conference on NO which has run since 1995 provides one of the only venues that brings together this diverse group and promotes transformational research ideas. The GRS will have the added value of helping to train and energize the next generation of researchers in the field. The need for greater understanding of how Nitric Oxide is critical to normal human function has only been made more apparent in the recent COVID pandemic. Nitric Oxide based detection and delivery systems are currently in use to not only treat patients, but to improve general health levels and improve resistant to disease. The investigators brought together by this conference have the potential to bring about true transformational change in human health.

项目概要该提案请求部分支持关于“一氧化氮信号传导的分子机制”的会议健康与疾病”作为戈登研究会议（GRC）和戈登研究研讨会（GRS） 2023 年 2 月 12 日至 17 日在加利福尼亚州文图拉举行。本次会议的广泛和长期目标是汇集该领域世界领先的研究人员，促进跨学科讨论和此次会议旨在加深我们对一氧化氮作为调节剂的了解。生理功能，因此是控制健康和疾病的重要目标。有兴趣强调恢复适当的一氧化氮信号传导如何减轻各种疾病 2023 年会议将包括糖尿病、高血压、哮喘和 COVID-19 相关肺炎。 GRC 是在 GRC 之前并与 GRC 同时举行的针对学员的 GRS 本次会议的具体目标。将召集超过 35 位领先专家，他们将展示该领域未发表的数据和见解一氧化氮研究将分为 9 个会议，全面涵盖该领域。会议重点关注心血管功能、信号分子机制、一氧化氮一氧化氮的产生和检测，以及一氧化氮在呼吸健康中的基础和转化作用。将重点研究，重点是生理信号传导和该系统的破坏下午的海报会议将让所有人能够有针对性地改善人类健康。通过会议主席和副主席选出的最有价值的摘要为这些主题做出贡献将尽一切努力鼓励研究生和学生的参与。 GRC 的博士后研究员此外，GRS 将专门针对学员，使他们能够我们将尽一切努力在轻松和额外支持的环境中展示他们的研究和互动。促进性别平等并纳入少数族裔/族裔和残疾人这一点的重要性。应用程序在于 GRC 和 GRS 提供的急需的论坛，以汇集和协同作用从事一氧化氮研究的国际研究团体的成员是独一无二的。它汇集了化学家、环境科学家、肺病和心血管医生。自 1995 年以来一直举办的 NO 戈登会议是唯一能将这些会议聚集在一起的场所之一。 GRS 将具有帮助的附加价值。培训和激励该领域的下一代研究人员需要更好地了解如何进行。一氧化氮对正常人体功能至关重要，在最近的新冠疫情中这一点更加明显基于一氧化氮的检测和输送系统目前不仅用于治疗患者，还用于治疗患者。研究人员聚集在一起，以提高总体健康水平并提高对疾病的抵抗力。会议有潜力为人类健康带来真正的变革。