Third International Symposium on Cyclic Vomiting syndrome and Cannabinoid Hyperemesis Syndrome

第三届周期性呕吐综合征和大麻素剧吐综合征国际研讨会

• 批准号: 10609378
• 负责人: Thangam Venkatesan
• 金额: $ 1.2万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10609378
• 关键词: Accident and Emergency department; Accounting; Address; Affect; Ambulatory Care; Applications Grants; Area; Basic Science; Biological; Cannabinoids; Cannabis; Caregivers; Celiac Disease; Childhood; Chronic; Chronic Disease; Clinical; Clinical Sciences; Clinical Treatment; Collaborations; Development; Digestive System Disorders; Discipline; Disease; Emergency department visit; Expenditure; Faculty; Fostering; Frequencies; Functional disorder; Funding; Future; Gastroenterology; Goals; Growth; Health; Health Personnel; Healthcare; Healthcare Systems; Hospitalization; Individual; Inflammatory Bowel Diseases; International; Journals; Knowledge; Lead; Learning; Mentorship; Methodology; Migraine; Minority Groups; Modality; National Institute of Diabetes and Digestive and Kidney Diseases; Nature; Nausea and Vomiting; Neurologist; Neurology; Neurosciences; Nurses; Ohio; Outcome; Patient Outcomes Assessments; Patient-Focused Outcomes; Patients; Peer Review; Periodicity; Physicians; Prevalence; Public Health; Publishing; Regulation; Research; Research Personnel; Research Priority; Resources; Science; Scientist; Syndrome; Time; Translational Research; Underrepresented Minority; Universities; Visit; Vomiting; Woman; Work; antagonist; base; care burden; career; cell motility; cost; diversity and inclusion; gut-brain axis; health care service utilization; improved; marijuana legalization; marijuana use; meetings; neuroregulation; next generation; novel strategies; novel therapeutics; posters; programs; symposium; targeted treatment; theories

Project summary Cyclic vomiting syndrome (CVS) is a common chronic disorder of gut-brain interaction (DGBI) and has a significant negative impact on patients, caregivers, and the health care system. Cannabinoid hyperemesis syndrome (CHS) has a similar clinical presentation to CVS but is thought to be due to heavy cannabis use and is being recognized with increasing frequency. How cannabis affects GI health is unclear and this is particularly important to understand given the rapid legalization of cannabis that has outpaced both funding and research. Despite CVS and CHS being important public health problems, there are significant knowledge gaps in part due to a lack of meetings that focus on this area which can foster collaboration between disciplines and accelerate research. Our current R13 grant application is a request to support a comprehensive scientific symposium, the Third International Symposium on Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome to be held at The Ohio State University in Columbus, Ohio on Nov 4-5, 2022. This will contribute to the overall goal of the NIDDK to foster collaborative research and mentorship opportunities, disseminate science-based information on digestive diseases and promote diversity and inclusion. The main objectives of our conference are 1. Provide an interdisciplinary exchange forum to advance research on biological mechanisms and clinical treatment of these interrelated disorders, CVS and CHS. 2. Foster interaction between early-stage investigators/trainees and senior investigators in basic and clinical and translational sciences to better understand mechanisms of nausea and vomiting 3. Provide a forum for health care providers and researchers to learn about various treatment approaches and novel strategies to manage CVS and CHS. 4. Promote inclusion with a particular emphasis on advancing the participation of women and individuals from underrepresented minority (URM) groups which will foster their professional development 5. Identify knowledge gaps, discuss methodological outcomes criteria for trials, and priorities for future research. Speakers will present cutting edge research on nausea and vomiting related to cyclic vomiting, cannabis use and cannabinoid hyperemesis, and migraine and discuss new modalities of therapy including neuromodulation, and CGRP antagonists in the treatment of these disorders. A scientific poster session will be held where junior investigators and trainees can present their work. The proceedings of the conference will be published in a peer-reviewed journal: Neurogastroenterology and Motility. Conference attendees will include scientists (neuroscience, gastroenterology, neurology), physicians (gastroenterology, neurologists, and geneticists), and other healthcare providers (nurses, advanced practitioners). Inclusion of URM, and early-stage investigator faculty will be a priority to facilitate the growth of the next generation of researchers.

项目概要 周期性呕吐综合征（CVS）是一种常见的肠-脑相互作用慢性疾病（DGBI），具有 对患者、护理人员和医疗保健系统产生重大负面影响。大麻素剧吐 综合征（CHS）与 CVS 具有相似的临床表现，但被认为是由于大量使用大麻和 越来越频繁地被认可。大麻如何影响胃肠道健康尚不清楚，这一点尤其重要 鉴于大麻​​合法化的速度已经超过了资金和研究的速度，理解这一点很重要。 尽管 CVS 和 CHS 是重要的公共卫生问题，但部分方面仍存在显着的知识差距 由于缺乏专注于这一领域的会议，而这些会议可以促进学科之间的合作 加速研究。我们当前的 R13 拨款申请是支持综合科学的请求 研讨会，第三届循环呕吐综合征与大麻素国际研讨会 剧吐综合症将于 2022 年 11 月 4 日至 5 日在俄亥俄州哥伦布市的俄亥俄州立大学举行。 将为 NIDDK 促进合作研究和指导机会的总体目标做出贡献， 传播有关消化系统疾病的科学信息并促进多样性和包容性。主要 我们会议的目标是 1. 提供一个跨学科交流论坛，以推进相关研究 这些相互关联的疾病、CVS 和 CHS 的生物学机制和临床治疗。 2.福斯特 早期研究人员/实习生和高级研究人员之间在基础和临床方面的互动 转化科学更好地了解恶心和呕吐的机制 3. 提供健康论坛 护理人员和研究人员了解各种治疗方法和新的管理策略 CVS 和 CHS。 4. 促进包容性，特别强调促进妇女和儿童的参与 来自代表性不足的少数群体 (URM) 的个人，这将促进他们的职业发展 5. 确定知识差距，讨论试验的方法结果标准以及未来研究的优先事项。 演讲者将介绍与周期性呕吐、大麻使用相关的恶心和呕吐的前沿研究 和大麻素剧吐和偏头痛，并讨论新的治疗方式，包括神经调节， 和 CGRP 拮抗剂治疗这些疾病。将举行科学海报会议，初级学生 研究人员和受训人员可以展示他们的工作。会议记录将出版在 同行评审期刊：神经胃肠病学和动力。会议与会者将包括科学家 （神经科学、胃肠病学、神经病学）、医生（胃肠病学、神经病学家和遗传学家），以及 其他医疗保健提供者（护士、高级执业医师）。纳入 URM 和早期研究者 教师将是促进下一代研究人员成长的优先事项。