Fast-Track Multimodal monitoring for neonatal neurocritical care

新生儿神经重症监护的快速多模式监测

• 批准号: 10601201
• 负责人: Tony Chris Carnes
• 金额: $ 26.04万
• 依托单位: MEDITRACE LLC
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-11 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10601201
• 关键词: Adherence; Admission activity; Birth; Blood Pressure; Brain Injuries; Caring; Cerebrum; Clinical; Clinical Practice Guideline; Clinical Research; Communication; Complex; Continuity of Patient Care; Data; Data Analyses; Data Collection; Data Display; Databases; Devices; Electronics; Environment; Equipment; Event; Evolution; Feedback; Functional disorder; Future; Generations; Goals; Grant; Health; Health Status; Hospital Information Systems; Hypoxic-Ischemic Brain Injury; Individual; Intervention; Life Support Care; Marketing; Measures; Medical Device; Modeling; Modification; Monitor; Morbidity - disease rate; Neonatal; Neonatal Intensive Care Units; Newborn Infant; Organ; Oxygen; Oxygen saturation measurement; Patient Care; Patient Monitoring; Patients; Pattern; Phase; Physiological; Population; Predictive Value; Process; Protocols documentation; Publications; Quality of Care; Severities; Stream; Surveys; System; Techniques; Technology; Time; Training; Treatment Effectiveness; Visualization; care providers; clinical decision support; data integration; design; effectiveness evaluation; experience; improved; improved outcome; information display; manufacture; multimodality; natural hypothermia; neonatal hypoxic-ischemic brain injury; neonatal patient; neonate; neurodevelopment; neuroprotection; next generation; novel; patient safety; personalized approach; prevent; prototype; remote monitoring; sensor; standard of care; success; support tools; tool; trend; trend analysis; usability; wireless

PROJECT SUMMARY In the US, approximately 1.5M babies are admitted to the Neonatal Intensive Care Unit (NICU) each year. Continuous monitoring of these patients is essential and the ability to quickly identify critical changes in a patients' health status is crucial to guiding daily care and therapy. While individual medical devices are helpful in this endeavor, integrating information from multiple devices onto one display and performing real-time analytics on this data enhances identification of the reasons for a change in patient condition and not just that a condition has changed. Continuously recording and providing both trending and real-time analysis for real changes in patient status can help optimize care decisions thus improving outcomes in this fragile population. In this grant we will build upon the success of the previously cleared Vital Sync multi-modal monitor that captures and analyzes information from over 100 devices in the NICU to help make the information actionable. The new device provides a continuous and retrospective view of patient condition so that care providers can objectively evaluate the effectiveness of treatment modifications. Real time assistance with identification of changes in patient condition helps to optimize new neuroprotective protocols. Improved review of prior patient condition through trending analysis and event marking assists with continuity of care across shift changes. The Phase I prototype is designed to evaluate the feasibility and usability of the tool in the NICU environment. The phase 2 system will support additional features including reduced connectivity burden and protocol support. Centraview 2.0 will be a platform for future modular upgrades that will enhance clinical decision support (CDS) in any ICU environment. Phase 1 Aim 1 – Create a prototype multimodal monitor for neonatal neurocritical care Based on existing experience and technology, we will design and prototype a new generation bedside monitoring system for collecting and displaying data from the key NICU medical devices at UFHealth. Phase 1 Aim 2 – Evaluate usability of the new system in a simulated NICU In a simulated NICU environment, we will create three neonatal patient scenarios and evaluate the system in a usability study with 8 NICU clinicians including surveys to determine perceived value, usability, and acceptance. Phase 2 Aim 1 – Expand connectivity, add protocol adherence, and enhance usability Clinical feedback from a successful Phase 1 will be used to improve the functionality and usability of CentraView 2. HIE protocol support will be added to the system along with several other new features including derived parameters and wireless data collection. Phase 2 – Aim 2 – Evaluate the effectiveness of CentraView 2 Clinical Assistant We will first collect baseline data for 6 months at UFHealth to measure adherence with several clinical practice guidelines (CPG). Next, we will install and train clinicians on the use of the CentraView system and determine if the system improves compliance with the CPGs.

项目概要 在美国，每年约有 150 万婴儿入住新生儿重症监护病房 (NICU) 对这些患者的持续监测至关重要，并且能够快速识别患者的关键变化。 患者的健康状况对于指导日常护理和治疗至关重要，而个人医疗设备也很有帮助。 在这一努力中，将来自多个设备的信息集成到一个显示器上并实时执行 对这些数据的分析可以增强对患者病情变化原因的识别，而不仅仅是 持续记录并提供真实的趋势和实时分析。 患者状况的变化有助于优化护理决策，从而改善这一脆弱人群的治疗结果。 在这笔赠款中，我们将在之前批准的 Vital Sync 多模式监测器的成功基础上再接再厉， 从 NICU 中的 100 多个设备捕获并嵌套信息，以帮助使信息具有可操作性。 新设备提供了患者状况的连续和回顾性视图，以便护理人员能够 客观评估治疗修改的有效性，并实时协助识别。 患者病情的变化有助于优化新的神经保护方案，改进对先前患者的审查。 通过趋势分析和事件标记来帮助保持轮班护理的连续性。 第一阶段原型旨在评估该工具在 NICU 环境中的可行性和可用性。 第 2 阶段系统将支持其他功能，包括减少连接负担和协议支持。 Centraview 2.0 将成为未来模块化升级的平台，将增强临床决策支持 (CDS) 在任何 ICU 环境中。 第一阶段目标 1 – 为新生儿神经重症监护创建原型多模式监测仪 基于现有的经验和技术，我们将设计和原型新一代床边监护 用于收集和显示 UFHealth 关键 NICU 医疗设备数据的系统。 第 1 阶段目标 2 – 评估新系统在模拟 NICU 中的可用性 在模拟 NICU 环境中，我们将创建三个新生儿患者场景并在一个环境中评估系统 通过 8 项 NICU 调查进行可用性研究，包括确定感知价值、可用性和接受度。 第 2 阶段目标 1 – 扩展连接性、增加协议遵从性并增强可用性 第一阶段成功的临床反馈将用于改进 CentraView 的功能和可用性 2. HIE协议支持将与其他几个新功能一起添加到系统中，包括派生 参数和无线数据采集。 第 2 阶段 – 目标 2 – 评估 CentraView 2 临床助理的有效性 我们将首先在 UFHealth 收集 6 个月的基线数据，以衡量对多种临床实践的依从性 接下来，我们将安装和培训圣徒如何使用 CentraView 系统，并确定是否可以使用。 该系统提高了 CPG 的合规性。