Fenway Community Health Center, Inc., Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

芬威社区健康中心有限公司站点联盟 - HIV/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心（UM2 临床试验可选）

• 批准号: 10599561
• 负责人: KENNETH H MAYER
• 金额: $ 43.35万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2029-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10599561
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent Medicine Trials Network; Age-Years; Boston; Caring; Clinical Trials; Clinical Trials Design; Collaborations; Communication; Communities; Community Health Education; Conduct Clinical Trials; Contracts; County; Drops; Enrollment; Ensure; Epidemic; Federally Qualified Health Center; Funding; Goals; Grant; HIV; HIV Seropositivity; Harm Reduction; Health; Health system; Housing; Human Resources; Infrastructure; Injecting drug user; Institutes; Intervention; Investigational Drugs; Justice; Laboratories; Leadership; Legal; Logistics; Massachusetts; Mediation; Medical; Monitor; Neighborhood Health Center; New England; New Hampshire; Pharmacy facility; Phase; Prevention; Primary Health Care; Process; Protocols documentation; Public Health; Research; Research Personnel; Research Priority; Research Project Grants; Resources; Risk; Schools; Sexual and Gender Minority Youth; Sexually Transmitted Diseases; Site; System; Work; Youth; authority; base; behavioral health; behavioral study; community engagement; design; improved; innovation; meetings; member; operation; participant retention; programs; recruit; screening; sexual HIV transmission; social health determinants; transmission process

ABSTRACT The Fenway Institute The Fenway Site Consortium (FSC) is designed to support, as one of the Site Consortiums, the application of Westat to serve as the Operations and Coordinating Center (OCC) in the next funding cycle of the Adolescent Trials Network (ATN) (RFA HD 23-021). The FSC will be based at The Fenway Institute (TFI) of Fenway Health (FH), a Federally Qualified Health Center in downtown Boston, Suffolk County. The long- term objectives of this proposal are to conduct the research projects identified by the ATN Executive Committee (EC) and Scientific Leadership Center (SLC), and optimize recruitment, monitoring, and retention of HIV- positive and at-risk youth into clinical trials designed to improve their health and to decrease HIV transmission and acquisition. To facilitate this process, the FSC will include other key FH programs, including the health center, which provides primary care for more than 9,500 youth 24 years of age and younger, with a focus on the affiliated Sidney Borum Health Center, which specializes in the care of sexual and gender minority youth, and the Public Health Programs that include programs focusing on health system navigation, drop in HIV/sexually transmitted infection (STI) screening, harm reduction programs for PWID, and programs addressing social determinants of health (e.g., housing and legal support). Additionally, we will utilize our grants management and contract negotiation teams to ensure optimal execution of all logistical and budgetary aspects of the grant. A primary member of the consortium will be JRI Health, which administers multiple programs for HIV-infected and at-risk youth in Boston and throughout Southern New England, including Providence, Worchester, and Southern New Hampshire. Other consortium members will include the Boston Public Health Commission, Boston Public Schools, the Massachusetts Department of Public Health (DPH), and collaborators in other local programs serving HIV-positive and at-risk youth. These partnerships will enable us to meet the proposed research goals of the SLC. In this project, we aim to: (1) Convene regular meetings of key consortium members to discuss new and ongoing protocols, to solicit their input regarding best practices for recruitment, community engagement, and participant retention, and for community education; (2) Convene a youth community advisory board (YCAB), which will provide input into youth priorities related to the work of the ATN, and guidance regarding best practices for community engagement and education; (3) Ensure optimal communication between local members of the FSC and the OCC and scientific leadership through routine meetings of local consortium members and engagement of consortium members in meetings convened by the OCC; (4) Actively participate in all relevant ATN activities, including providing site representatives to governance committees of the ATN, and site investigators to represent the FSC on ATN protocols.

摘要 芬威学院 芬威场地联盟 (FSC) 作为场地联盟之一，旨在支持以下应用： Westat 将作为青少年项目下一个资助周期的运营和协调中心 (OCC) 审判网络 (ATN) (RFA HD 23-021)。 FSC 将设在芬威的芬威学院 (TFI) Health (FH) 是位于萨福克县波士顿市中心的联邦合格健康中心。长期来看 该提案的目标是开展 ATN 执行委员会确定的研究项目 （EC）和科学领导中心（SLC），并优化艾滋病毒的招募、监测和保留 积极和高危青少年参与临床试验，旨在改善他们的健康并减少艾滋病毒传播 和收购。为了促进这一进程，FSC 将纳入其他重要的 FH 计划，包括健康 该中心为超过 9,500 名 24 岁及以下的青少年提供初级保健，重点关注 附属的悉尼博鲁姆健康中心（Sidney Borum Health Centre）专门为性少数和性别少数青少年提供护理， 以及公共卫生计划，其中包括侧重于卫生系统导航的计划， HIV/性传播感染 (STI) 筛查、吸毒者减害计划和计划 解决健康的社会决定因素（例如住房和法律支持）。此外，我们将利用我们的 赠款管理和合同谈判团队确保所有后勤和预算的最佳执行 补助金的各个方面。该联盟的主要成员将是 JRI Health，该公司管理多个 波士顿和新英格兰南部地区针对艾滋病毒感染者和高危青少年的计划，包括 普罗维登斯、伍彻斯特和新罕布什尔州南部。其他财团成员将包括波士顿 公共卫生委员会、波士顿公立学校、马萨诸塞州公共卫生部 (DPH) 和 为艾滋病毒呈阳性和高危青少年服务的其他当地项目的合作者。这些合作伙伴关系将使我们能够 以满足 SLC 提出的研究目标。在本项目中，我们的目标是： (1) 定期召开会议 主要联盟成员讨论新的和正在进行的协议，征求他们对最佳实践的意见 用于招募、社区参与、参与者保留以及社区教育； （二）召集 青年社区咨询委员会（YCAB），该委员会将为与青年工作相关的优先事项提供投入 ATN 以及有关社区参与和教育最佳实践的指南； (3) 确保最优 FSC 和 OCC 当地成员之间的沟通以及通过例行的科学领导 当地财团成员的会议以及财团成员参加由当地财团召集的会议 奥委会； (4) 积极参与所有相关的ATN活动，包括派遣现场代表 ATN 治理委员会以及代表 FSC 参与 ATN 协议的现场调查员。