Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE)

罗德岛医院伤害控制卓越生物医学研究中心 (COBRE)

• 批准号: 10598059
• 负责人: Michael J Mello
• 金额: $ 243.68万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2027-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10598059
• 关键词: Acceleration; Accident and Emergency department; Address; Advisory Committees; Age Years; Cause of Death; Centers of Research Excellence; Child; Childhood; Collaborations; Committee Members; Derivation procedure; Development; Discipline; Dissemination and Implementation; Doctor of Philosophy; Dryness; Elderly; Emergency Department patient; Emergency department visit; Ensure; Epidemic; Faculty; Fall prevention; Fracture; Funding; Future; Growth; Health; Hospitals; Individual; Infrastructure; Injury; Institution; Lead; Leadership; Life Cycle Stages; Mentors; Mentorship; Mission; Pilot Projects; Policies; Positioning Attribute; Production; Prospective Studies; Research; Research Activity; Research Personnel; Research Project Grants; Research Proposals; Research Support; Rhode Island; Running; Science; Scientist; Seasons; Services; Training; United States National Institutes of Health; Woman; Work; career development; clinical predictors; combat; design; digital; digital health; early-career faculty; emerging adult; improved; injured; injury burden; injury prevention; innovation; marijuana use; multidisciplinary; organizational structure; population health; post-traumatic symptoms; preventive intervention; programs; research study; research to practice; senior faculty; sound; telehealth; trauma exposure

PROJECT SUMMARY (Overall) Injury is the leading cause of death for individuals 1-44 years of age and contributes to over 30 million emergency department visits annually1. There is a tremendous need for greater scientific understanding and strategies to combat the injury epidemic yet injury control research is underfunded compared to other leading causes of death2,3. We propose to establish the Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE). The proposed Center would be the first and only NIH-funded COBRE research center to focus solely on injury control. The objective of this proposal is to establish and build a COBRE Center to support the research activities of project research leaders to ensure their transition to independently funded scientists. This objective will be met through the following specific aims: 1) establish the cores (Administrative Core, Injury Control Digital Innovation Core & Injury Control Research to Practice and Policy Core) needed to develop and sustain a thematic multidisciplinary center of research excellence on injury control and to 2) support the selection, mentorship, and career development of early career faculty through the COBRE’s research studies and a pilot study program. The RIH Injury Control COBRE research studies will target the entire spectrum of injury prevention (primary, secondary, tertiary) with individuals across the lifecycle (children, emerging adults and older adults). The three initial RPLs are three women junior faculty with outstanding potential to make significant contribution to injury science research: Leslie Brick, PhD, Elizabeth Goldberg, MD, ScM and Stephanie Ruest, MD, MPH. In addition, a pilot project program will support research proposals for future junior investigators to continue the growth of independent researchers. This mentored pilot program will allow early work to commence on important injury control topics with innovative research and allow those projects to proceed and become later Research Projects within the COBRE or to progress directly to independent funding. RIH has a strong core of senior researchers in the field of injury control science; however, our pipeline of researchers will run dry if we do not expand and replenish researchers capable of injury control research excellence. The RIH Injury Control COBRE will bring together junior investigators, senior faculty and advisory committee members to build a center which produces high level, independent researchers equipped to address and improve the substantial burden injury has on population health. It will be continuously and rigorously evaluated allowing for constant improvement and preparing our institution to accelerate its production of high-quality innovative injury control research and researchers.

项目概要（总体） 伤害是 1-44 岁人群死亡的主要原因，导致超过 3000 万人遭遇紧急情况 每年部门访问1非常需要更深入的科学理解和策略 与伤害流行作斗争，但与造成伤害的其他主要原因相比，伤害控制研究资金不足 死亡2、3。我们提议建立罗德岛医院伤害控制生物医学研究中心 拟议的中心将是第一个也是唯一一个由 NIH 资助的 COBRE 研究中心。 该提案的目标是建立一个 COBRE 中心来支持伤害控制。 项目研究负责人的研究活动，以确保他们过渡为独立资助的科学家。 这一目标将通过以下具体目标来实现：1）建立核心（行政核心、伤害 控制数字创新核心和伤害控制研究到实践和政策核心）需要开发和 维持伤害控制方面的专题多学科卓越研究中心，并 2) 支持选择， 通过 COBRE 的研究和试点，为早期职业教师提供指导和职业发展 RIH 损伤控制 COBRE 研究将针对整个损伤范围。 对整个生命周期的个人（儿童、新兴成人和老年人）进行预防（一级、二级、三级） 最初的三名 RPL 是三名具有杰出潜力的女性初级教师。 对伤害科学研究的贡献：Leslie Brick 博士、Elizabeth Goldberg 医学博士、ScM 和 Stephanie Ruest， 此外，试点项目计划将为未来初级研究人员的研究提案提供支持。 这一指导性试点计划将继续促进独立研究人员的发展，从而使早期工作能够开始。 通过创新研究来研究重要的伤害控制主题，并允许这些项目继续进行并在以后进行 COBRE 内的研究项目或直接获得独立资助的研究项目具有强大的核心。 然而，如果我们这样做，我们的研究人员队伍就会枯竭。 不扩大和补充能够进行卓越伤害控制研究的研究人员。 COBRE 将汇集初级研究员、高级教师和咨询委员会成员来建立一个中心 它培养高水平的独立研究人员，有能力解决和改善沉重的负担 将持续、严格地评估伤害对人口健康的影响。 改进并准备我们的机构加速生产高质量的创新伤害控制 研究和研究人员。