Developmental Research Program (DRP)

发展研究计划（DRP）

基本信息

批准号：
10263348
负责人：
KATHRYN I POLLAK
金额：
$ 9.87万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-14 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10263348
关键词：
Advertisements American Association of Cancer Research Attention Award Basic Science Cancer Science Clinical Clinical Research Complement Development Diagnosis Doctor of Philosophy Ensure Evaluation Evolution Faculty Faculty Recruitment Feedback Funding Funding Mechanisms Future Goals Grant Individual Institutes Institution Intercept Journals Leadership Malignant Neoplasms Minority Patient-Focused Outcomes Peer Review Pilot Projects Population Research Prevention Probability Process Progress Reports Research Research Personnel Research Project Grants Review Committee Source Testing Translational Research United States National Institutes of Health Universities Woman Work cancer health disparity experience improved improved outcome medical schools meetings novel novel strategies programs skills translational cancer research women faculty

项目摘要

ABSTRACT – Developmental Research Program The Developmental Research Program (DRP) is a critical component of the Duke Cancer Health Disparities (DCHD) P20 SPORE, supporting (1) pilot research projects with translational potential relevant to cancer disparities and (2) the participation of early stage and experienced investigators from other fields to work in translational cancer research. Projects are encouraged to test novel concepts and paradigms that bring new approaches into the field to further advance our understanding of cancer health disparities and to improve prevention, diagnosis, interception, and/or treatment. The DRP will specifically target projects that have a strong likelihood of developing into full projects for our planned DCHD P50 SPORE application or independent research projects (e.g. NIH R01 or similar funding mechanisms). Special attention will be given to promoting participation of women and minorities. The coordinated efforts of Co-Directors Gerard Blobe, MD, PhD, and Kathryn Pollak, PhD, with the DRP Scientific Review Committee (DRP-SRC), will ensure a proactive, productive DRP that prioritizes impactful pilot projects and faculty recruitment, and is well integrated into the overall P20 SPORE. The DRP will identify and support meritorious basic, translational, population, or clinical research projects that have a high probability of impacting cancer disparities at the level of prevention, diagnosis, interception, or treatment (Aim 1); attract outstanding new and/or experienced investigators, currently not working on cancer disparities, to pursue cancer disparities research (Aim 2); facilitate collaborative translational research to test novel concepts and paradigms relevant to cancer disparities in prevention, diagnosis, interception, or treatment (Aim 3); and evaluate progress on funded projects and facilitate their evolution into full SPORE projects or into independently funded projects (Aim 4). To accomplish these Aims, the DRP will award $100,000 each year to fund at least one promising project per year. Awardees will be eligible for renewed funding for one additional year, if satisfactory progress is made and an acceptable proposal and plan for the second year are presented. Strategies to solicit DRP applications will include direct solicitation to all faculty in the Duke Cancer Institute, Duke School of Medicine, and Duke University. In addition, cancer disparities research programs at other institutions nationwide will be contacted, and advertisements will be placed in appropriate clinical and scientific journals to attract collaborative applications from outside of Duke. All DRP applications will undergo a transparent multi-tiered peer review process. DRP awardees will be required to present progress reports on their projects on a rotating basis at the bi-weekly Executive Committee meetings, where they will receive feedback. The DRP and its processes will be evaluated annually as part of the DCHD P20 SPORE evaluation, and improvements instituted for the next cycle of solicitation, review, and award.

摘要——发展研究计划发展研究计划 (DRP) 是杜克大学癌症健康差异的重要组成部分 (DCHD) P20 SPORE，支持 (1) 具有与癌症相关的转化潜力的试点研究项目差异以及（2）来自其他领域的早期和经验丰富的研究人员的参与鼓励转化癌症研究项目测试带来新成果的新概念和范例。进入该领域的方法进一步增进我们对癌症健康差异的理解并改善 DRP 将专门针对具有强大功能的项目。开发成我们计划的 DCHD P50 SPORE 应用或独立研究的完整项目的可能性项目（例如 NIH R01 或类似的资助机制）将特别关注促进参与。联合主任 Gerard Blobe（医学博士、哲学博士）和 Kathryn Pollak 的协调努力，博士与 DRP 科学审查委员会 (DRP-SRC) 将确保积极主动、富有成效的 DRP 优先考虑有影响力的试点项目和教师招聘，并很好地融入到整个 P20 SPORE 中。 DRP 将识别并支持有功绩的基础、转化、人口或临床研究项目很有可能在预防、诊断、拦截或治疗层面影响癌症差异（目标 1）；吸引目前不从事癌症差异研究的优秀新研究人员和/或经验丰富的研究人员，开展癌症差异研究（目标 2）；促进合作转化研究以测试新概念以及与预防、诊断、拦截或治疗方面的癌症差异相关的范式（目标 3）；评估资助项目的进展并促进其发展为完整的 SPORE 项目或独立项目资助项目（目标 4）为了实现这些目标，DRP 每年将奖励 100,000 美元，资助至少一个项目。每年有前途的项目如果令人满意，将有资格获得额外一年的资助。取得了进展，并提出了第二年可接受的提案和计划。 DRP 申请将包括直接向杜克大学癌症研究所、杜克大学癌症研究所的所有教员进行征集。此外，全国其他机构的癌症研究项目也存在差异。将与您联系，并在适当的临床和科学期刊上刊登广告以吸引来自杜克大学外部的协作应用程序将经历透明的多层对等。 DRP 获奖者将被要求轮流提交其项目的进度报告。在每两周一次的执行委员会会议上，他们将收到 DRP 及其流程的反馈。将每年进行一次评估，作为 DCHD P20 SPORE 评估的一部分，并为下一次制定改进征集、评审、奖励的循环。