Cancer Center Support Grant

癌症中心支持补助金

基本信息

批准号：
9242362
负责人：
MICHAEL A CALIGIURI
金额：
$ 49.83万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-09-12 至 2020-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9242362
关键词：
Address African American Agriculture Amish Area Arts Basic Science Behavior Behavior Therapy Behavioral Behavioral Sciences Biology Breast Cancer Center Cancer Center Support Grant Cancer Control Cancer Survivorship Caring Catchment Area Categories Clinical Clinical Research Collaborations Colorectal Communication Research Communities Community Networks Comprehensive Cancer Center Dentistry Descriptor Detection Doctor of Philosophy Ecology Education Enrollment Epidemiology Etiology Food Fostering Funding Future Genetic Goals Health Policy High Prevalence Hispanics Human Human Papilloma Virus Vaccine Incidence Industry Intervention Investigational Therapies Investments Journals Knowledge Laws Leadership Life Lung Malignant Neoplasms Malignant neoplasm of prostate Medicine Mission Molecular Epidemiology Molecular Genetics Morbidity - disease rate Multicultural Education National Cancer Program Nursing Education Obesity Ohio Outcome Outreach Research Participant Patient-Focused Outcomes Patients Pediatric Hospitals Peer Review Policies Population Prevention Prostate Public Health Publications Publishing Research Research Personnel Resources Risk Behaviors Rural Scanning Science Scientist Screening for cancer Smoke Strategic Planning Stress TNFRSF5 gene Testing Tobacco Tobacco use Toxic effect Training Translating Translational Research Underserved Population Universities University resources Vision anticancer research cancer prevention clinical care college falls genetic epidemiology inner city innovation malignant breast neoplasm member mortality next generation outreach population based prevent programs research study screening social survivorship underserved minority

项目摘要

DESCRIPTION (provided by applicant): The Cancer Control (CC) Program at the Ohio State University Comprehensive Cancer Center (OSUCCC), led by Electra D. Paskett, PhD, MSPH and Mary Ellen Wewers, RN, PHD, MPH, has 52 members from 19 OSU departments within the OSU Colleges of Medicine, Public Health, Arts and Sciences, Law, Nursing, Education and Human Ecology, Dentistry, and Food, Agricultural and Environmental Sciences, as well as Nationwide Children's Hospital and Cincinnati Children's Hospital. Program members provide a wealth of behavioral, basic, clinical, policy, outcomes, and social scientific knowledge and expertise not only to the CC Program, but to the OSUCCC as a whole. The overall CC Program goal is to conduct research to reduce the incidence, mortality and morbidity of cancer, which is accomplished by employing a transdisciplinary research team approach. The Specific Aims of the CC Program are to: 1) Identify molecular, genetic, and behavioral factors related to cancer incidence and mortality; 2) Develop and test behavioral interventions to prevent or detect cancer early; and, 3) Assess and intervene on issues of cancer survivorship. An additional developing aim of the CC Program is to address policy in relation to cancer prevention, detection, and care. Within these aims, research focuses on cross-cutting themes including underserved/minority populations within our catchment area, communication research, tobacco use and toxicity (including regulatory science), and behavioral strategies that capitalize on our members' strengths, such as epidemiology, biology and behavior. The program now has 2 NCI P50-funded Centers, both showcasing not only our multi-level focus but also the transition from observational to interventional studies. In addition, many of our interventions, e.g., Patient Navigation and Bio-Behavioral Intervention to Reduce Stress after Breast Cancer, have been incorporated into clinical care. Moreover, our research has contributed to policy changes, most notably the establishment of a smoke-free campus at OSU. During this past funding period (2009 - 2014), the Program members published a total 611 articles in peer-reviewed journals of which 32% have intra-programmatic collaboration, 20% have inter-programmatic collaborations, and 404 (66%) of the publications represent multi-institutional collaborations. Many of these publications fall within each of these categories bringing the total collaborative publications to 85%. CC Program funding stands at $6.8M of which $6.2M is peer-reviewed funding and of that, $3.9M (63%) is NCI funding. CC Program investigators have enrolled 9,205 participants to research studies over the last 5 years, 64% to externally peer-reviewed studies and 34% to institutional studies, 1.2% to cooperative trial group studies and 0.8% to industry studies. Of these, 6,964 (76%) were enrolled on interventional studies and 2,241 (24%) on non-interventional studies. Future goals focus on increasing research in: 1) policy, allowing us to take advantage of health care policy initiatives; 2) molecular and genetic epidemiology and 3) patient outcomes, fostering more inter-programmatic research with clinicians.

描述（由申请人提供）：俄亥俄州立大学综合癌症中心 (OSUCCC) 的癌症控制 (CC) 项目由 Electra D. Paskett 博士、公共卫生硕士和 Mary Ellen Wewers 注册护士、哲学博士、公共卫生硕士领导，有 52 名成员来自俄勒冈州立大学医学院、公共卫生学院、艺术与科学学院、法律学院、护理学院、教育与人类生态学学院、牙科学院、食品学院、农业与环境学院的 19 个院系科学以及全国儿童医院和辛辛那提儿童医院计划成员不仅为 CC 计划，而且为整个 OSUCCC 提供丰富的行为、基础、临床、政策、结果和社会科学知识和专业知识。 CC 计划的总体目标是开展研究以降低癌症的发病率、死亡率和发病率，这是通过采用跨学科研究团队方法来实现的。CC 计划的具体目标是： 1) 识别分子、遗传和行为因素。与癌症有关发病率和死亡率；2) 制定和测试早期预防或检测癌症的行为干预措施；3) 评估和干预癌症生存问题。在这些目标中，研究重点是跨领域主题，包括我们服务范围内的服务不足/少数民族人口、传播研究、烟草使用和毒性（包括监管科学）以及利用我们成员优势的行为策略，例如作为流行病学，该计划现在拥有 2 个 NCI P50 资助的中心，不仅展示了我们的多层次重点，而且还展示了我们的许多干预措施，例如患者导航和生物行为。此外，我们的研究还促进了政策变化，尤其是在过去的资助期间在俄勒冈州立大学建立了无烟校园。 (2009 - 2014)，项目成员在同行评审期刊上发表了总共 611 篇文章，其中 32% 进行项目内合作，20% 进行项目间合作，404 篇 (66%) 出版物代表多机构其中许多出版物属于这些类别，使 CC 计划资助总额达到 85%，其中 620 万美元。同行评审资金，其中 390 万美元（63%）是 NCI 资助，CC 项目研究人员在过去 5 年招募了 9,205 名参与者进行研究，其中 64% 参与外部同行评审研究，34% 参与机构研究，1.2 % 参与合作试验组研究，0.8% 参与行业研究，其中 6,964 人 (76%) 参与了干预研究，2,241 人参与。 (24%) 未来的目标集中在增加以下方面的研究：1) 政策，使我们能够利用医疗保健政策举措；2) 分子和遗传流行病学；3) 患者结果，促进更多的跨项目研究。与信徒一起研究。