Research Training in Pediatric Nephrology

小儿肾脏病学研究培训

• 批准号: 9070063
• 负责人: CARLTON MATTHEW BATES
• 金额: $ 25.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9070063
• 关键词: Childhood; Nephrology; Research Training

 DESCRIPTION (provided by applicant): This renewal application seeks to sustain NIH funding to train pediatric nephrology fellows at the University of Pittsburgh/Children's Hospital of Pittsburgh of UPMC to become successful clinician scientists. Few pediatric nephrologists have active R01 grants and few Pediatric Nephrology Divisions have multiple NIH funded faculty. Furthermore, there are few dedicated pediatric nephrology T32 training grant positions available to train fellows. Given current financial difficulties, it has also been difficult for Medical Schols and Departments of Pediatrics to commit resources to training fellows to do research. Taken together, there are often inadequate resources and few mentors available to train pediatric nephrologists to do basic, translational, or clinical research. The resulting paucity of pediatric nephrology fellows that develop successful careers in research significantly impedes progress in deciphering pathophysiology and treatments for kidney diseases that affect children (and subsequently adults). The objective of this program has been to train pediatric nephrology fellows to become clinician researchers. Through the first four years of the program, we have trained six fellows, including an underrepresented minority, all of whom are moving in academic positions and many of whom have (or are planning to have) significant research programs. We are seeking to renew the currently funded three positions for PGY5 or PGY6 pediatric nephrology fellows and to add a fourth position that could be used for training medical fellows or PhD postdoctoral fellows. This training program is uniquely positioned in that there are five (soon to be six) externally-funded Pediatric Nephrology faculty members (two of which are currently qualified to be mentors, which will increase as junior faculty research programs mature). This is one of the largest Pediatric Nephrology divisions in the country with ten (soon to be 11) MD and PhD faculty and a robust clinical program that has enhanced fellow recruitment. There are also several potential mentors outside of the Pediatric Nephrology Division at the University of Pittsburgh that have significant track records of NIH funding. Moreover, the University of Pittsburgh ranks in the top five for NIH awards obtained from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The proposed faculty mentors in this program also have had a significant track record of mentoring post-doctoral trainees. The research areas are very diverse and include mentors focused on basic, translational, and/or clinical research. The environment is also very supportive and includes coursework and optional degrees for fellows (e.g. Fundamentals of Biomedical Science courses for basic research and Certificates in Clinical Research and Masters in Clinical Research, Public Health, and Bioethics for clinical/translational research). The training program is also very focused on increasing the diversity of trainees and on education regarding the responsible conduct of research. In summary, the breadth of the research opportunities, emerging training track record, and outstanding environment make this institution an excellent place to train pediatric nephrology fellows to become clinician scientists.

 描述（由应用程序提供）：此续签申请旨在维持NIH资金来培训匹兹堡大学/匹兹堡大学匹兹堡大学的小儿肾脏科学研究员，以成为成功的临床科学家。很少有儿科肾病学家拥有活跃的R01补助金，很少有小儿肾脏病学部门具有多个NIH资助的教职员工。此外，很少有专门的小儿肾脏病T32培训赠款职位可用于训练研究员。鉴于当前的财务困难，医学学士和儿科部门也很难将资源投入培训研究员进行研究。综上所述，通常没有资源不足，很少有指导者可以培训小儿肾病学家进行基本，翻译或临床研究。小儿肾脏科学研究员的导致缺乏研究的研究很大程度上阻碍了破译的病理生理学和对影响儿童（以及随后成年人）的肾脏疾病的治疗的进展。该计划的目的是培训小儿肾脏科学家成为临床研究人员。在该计划的前四年中，我们已经培训了六名研究员，其中包括代表性不足的少数派，所有这些人都在学术职位上行动，其中许多人（或计划）拥有重要的研究计划。我们正在寻求续签目前资助的PGY5或PGY6小儿肾脏科研究员的三个职位，并添加可用于培训医疗研究员或博士后博士博士学位的第四位。该培训计划的独特位置是，有五个（即将是六个）外部资助的小儿肾脏病学院成员（其中两个目前有资格成为导师，这将随着初级教师研究计划的成熟而增加）。这是该国最大的儿科肾脏科之一，有十个 BE 11）医学博士和博士学位教师以及一项强大的临床计划，增强了同胞招聘。匹兹堡大学小儿肾脏病科学系以外的几位潜在导师具有NIH资金的重大记录。此外，匹兹堡大学在美国国家糖尿病研究所，消化和肾脏疾病（NIDDK）获得的NIH奖项中排名前五。该计划中的拟议教师导师也有脑力学后学员的重大记录。研究领域非常多样化，包括专注于基本，翻译和/或临床研究的导师。环境也非常支持，包括研究员的课程和可选学位（例如，临床研究，公共卫生和临床/翻译研究的临床研究，公共卫生和生物伦理学的基础研究和证书的生物医学科学课程和证书）。该培训计划还非常专注于增加学员的多样性以及有关负责任的研究的教育。总而言之，研究机会的广度，新兴的培训记录和杰出的环境使该机构成为培训儿科肾脏科学研究员成为临床科学家的好地方。