Center for Pediatric Brain Health

儿科脑健康中心

• 批准号: 10580767
• 负责人: Tony W Wilson
• 金额: $ 243.06万
• 依托单位: FATHER FLANAGAN'S BOYS' HOME
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2027-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10580767
• 关键词: Acceleration; Advisory Committees; Area; Brain; Centers of Research Excellence; Child; Child Care; Childhood; Cognitive; Collaborations; Collection; Communities; Community Health; Community Outreach; Computers and Advanced Instrumentation; Core Facility; Development; Educational workshop; Ensure; Equipment; Evaluation; Event; Extramural Activities; Faculty; Family; Fostering; Funding; Future Generations; Future Teacher; Goals; Growth; Health; Home; Hospitals; Human; Image; Imaging technology; Infrastructure; Institution; Internships; Lead; Magnetic Resonance Imaging; Magnetoencephalography; Mentors; Methods; Mission; Monitor; National Institute of General Medical Sciences; Nebraska; Neurosciences; Neurosciences Research; Participant; Pilot Projects; Population; Postdoctoral Fellow; Publications; Publishing; Registries; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Senior Scientist; Series; Site; Structure; System; Training; Training Programs; Training and Education; Voice; Work; boys; brain health; career; career development; cohort; collaborative environment; experience; graduate student; improved; innovation; instrumentation; multidisciplinary; multimodal neuroimaging; neural; neuroimaging; neuroregulation; next generation; novel; outreach; prisma; programs; research and development; square foot; training opportunity; welfare

Abstract/Summary: Overall Component This application for a Center of Biomedical Research Excellence (COBRE) would initiate a Center for Pediatric Brain Health to manage, support, and expand developmental neuroimaging and pediatric neuroscience research at Boys Town National Research Hospital (BTNRH) in Omaha, Nebraska. It is an opportune moment for pediatric neuroscience at BTNRH, as an organization-wide initiative to expand in this area has resulted in numerous faculty hires and the construction of a new state-of-the-art 15,000+ square feet Institute for Human Neuroscience. The proposed Center for Pediatric Brain Health will organize and support these new resources under a central umbrella, and provide critical programs to help grow the community and build cohesiveness around a common theme of pediatric neuroscience and brain health. The key components of the Center include an Administrative Core, one research core (i.e., the Neural Quantification & Imaging Core), four research project leaders (RPLs), a Supervisory & Mentoring Committee, and a cohort of established pediatric neuroscientists. Upon initiation of the Center, the Administrative Core will implement a comprehensive research support structure that includes mentoring and career developing resources, a pilot projects program, extensive training opportunities, two distinct seminar series, community outreach, and broad support of key research infrastructure (e.g., participant registry, shared research spaces). Training opportunities will include technical workshops, as well as internships and a postdoctoral neuroimaging training program for fostering the next generation of graduate students and Center faculty. In parallel, the Administrative Core will promote the launch of four RPLs and implement a career development and evaluation system, which will include a Supervisory & Mentoring Committee comprised of 10 senior scientists who will monitor progress and ensure each RPL and their two co-mentors reach critical milestones. Finally, the new Neural Quantification & Imaging Core will support and provide direct access to state- of-the-art instrumentation for pediatric neuroimaging, including a new 3-Tesla Siemens Prisma magnet, two Neo magnetoencephalographic (MEG) imaging units, a mock MRI scanner, and other major equipment, and will provide comprehensive analytical support for the most advanced neuroimaging analyses currently available. Notably, the Core will be the only site in the world to host two MEG Neo systems for quantifying human brain dynamics. The new Center will also support a cohort of senior scientists with expertise spanning multiple pediatric populations and different imaging technologies. Finally, the Center will receive exceptional institutional support, including funds for pilot projects, Core staffing, internships, major equipment expenses, and other initiatives, and will be directed by Dr. Tony Wilson who is a developmental cognitive neuroscientist with extensive experience in multimodal neuroimaging and an exceptional track record of extramural support, publications, and mentoring. Taken together, the expansive resources, support, and expertise within the new Center for Pediatric Brain Health will ensure that it has a major long-term impact on pediatric neuroscience research at BTNRH and beyond.

摘要/总结：总体组成部分 该生物医学研究卓越中心 (COBRE) 的申请将启动一个儿科中心 Brain Health 管理、支持和扩展发育神经影像和儿科神经科学研究 在内布拉斯加州奥马哈男孩镇国家研究医院 (BTNRH)。对于儿科来说，这是一个好时机 BTNRH 的神经科学作为一项在整个组织范围内扩展该领域的举措，已取得了许多成果 聘请教职人员并建造了一座占地 15,000 多平方英尺、最先进的新人类神经科学研究所。 拟议的儿科脑健康中心将在中央机构的领导下组织和支持这些新资源 保护伞，并提供关键计划来帮助发展社区并围绕共同目标建立凝聚力 儿科神经科学和大脑健康的主题。该中心的主要组成部分包括行政部门 核心，一个研究核心（即神经量化和成像核心），四名研究项目负责人（RPL）， 一个监督和指导委员会，以及一群知名的儿科神经科学家。启动后 该中心的行政核心将实施全面的研究支持结构，其中包括 指导和职业发展资源、试点项目计划、广泛的培训机会、两个 独特的研讨会系列、社区外展以及关键研究基础设施的广泛支持（例如，参与者 注册表、共享研究空间）。培训机会包括技术研讨会和实习 以及培养下一代研究生的博士后神经影像培训计划 中心师资力量。与此同时，行政核心将推动四个 RPL 的启动并实施职业生涯 开发和评估体系，其中包括由 10 名成员组成的监督和指导委员会 资深科学家将监控进展并确保每个 RPL 及其两名共同导师达到关键水平 里程碑。最后，新的神经量化和成像核心将支持并提供对状态的直接访问 最先进的儿科神经影像仪器，包括一个新的 3 特斯拉西门子 Prisma 磁铁、两个 Neo 脑磁图 (MEG) 成像装置、模拟 MRI 扫描仪和其他主要设备，并将 为当前最先进的神经影像分析提供全面的分析支持。 值得注意的是，Core 将是世界上唯一拥有两个用于量化人脑的 MEG Neo 系统的站点 动力学。新中心还将支持一群拥有多个儿科专业知识的资深科学家 人群和不同的成像技术。最后，该中心将获得特殊的机构支持， 包括试点项目、核心人员配置、实习、主要设备费用和其他举措的资金，以及 由托尼·威尔逊博士指导，他是一位具有丰富经验的发展认知神经科学家 在多模式神经影像学方面拥有丰富的经验，并在校外支持、出版物和指导方面拥有出色的记录。 总而言之，新的儿科脑健康中心拥有丰富的资源、支持和专业知识 将确保它对 BTNRH 及其他机构的儿科神经科学研究产生重大的长期影响。