UNC Oncology Clinical Translational Research Training Program

北卡罗来纳大学肿瘤学临床转化研究培训计划

• 批准号: 8921117
• 负责人: NORMAN E SHARPLESS
• 金额: $ 13.51万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-17 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8921117
• 关键词: Adult; Advisory Committees; Area; Basic Science; Cancer Hospital; Clinical; Clinical Oncology; Clinical Research; Comprehensive Cancer Center; Educational Curriculum; Enrollment; Ethnic Origin; Faculty; Fellowship Program; Foundations; Funding; Gastroenterology; Genetic Medicine; Goals; Health; Hematology; Hepatology; Intellectual Property; Left; Malignant Neoplasms; Mentors; Mentorship; Modeling; Monitor; Mus; North Carolina; Outcome; Pediatric Hematology; Phase; Physicians; Program Reviews; Progress Reports; Qualifying; Radiation Oncology; Records; Recruitment Activity; Research Personnel; Research Support; Research Training; Resources; Role; Training; Training Programs; Translational Research; UNC Lineberger Comprehensive Cancer Center; Universities; anticancer research; commercialization; experience; medical schools; member; novel therapeutics; oncology; patient oriented; patient oriented research; phase I trial; professor; programs

DESCRIPTION (provided by applicant): In this application, the University of North Carolina at Chapel Hill (UNC) Divisions of Adult and Pediatric Hematology/Oncology, the Department of Radiation Oncology, the UNC Lineberger Comprehensive Cancer Center (LCCC) and the Division of Gastroenterology and Hepatology propose to renew funding for the UNC Oncology Clinical/ Translational Research Training Program (OCT-RTP). All four of the components will contribute mentors and research resources to the proposed training program, and all components except UNC-LCCC will contribute scholars. OCT-RTP will admit two scholars per year. The PI, Dr. Norman Sharpless, is Professor of Medicine and Genetics, a member of the Hematology/Oncology division, and is the LCCC Associate Director for Translational Research. Dr. Sharpless has extensive experience in cancer research in the areas of murine models, novel therapeutics, Phase I trials and commercialization of intellectual property. Dr Thomas Stinchcombe, Associate Professor and Hematology/Oncology fellowship program director, has newly assumed the role of Program Director. The program's objectives are to establish a highly motivated and rigorously trained cadre of physician clinical researchers who are competitive in seeking research support and who will become successful, independent patient-oriented cancer investigators. Training resources that will be available for the OCT-RTP include: the Lineberger Comprehensive Cancer Center, the North Carolina Cancer Hospital, the UNC School of Medicine K30 Clinical Research Curriculum and the UNC Program on Ethnicity Culture and Health Outcomes. The goals of the OCT-RTP are to increase the quality and quantity of patient-oriented research, including all phases of clinical research and particularly that involving a translational component. The foundation of the proposed training program will be the participation of highly qualified basic science and clinical mentors assigned to each scholar with mentoring activities coordinated by a mentor integration panel. An internal advisory committee that includes senior faculty from each of the four components will select and monitor the progress of scholars, while an external advisory committee will review the program annually. Since its inception, the OCT-RTP has enrolled six Scholars who records are detailed in the progress report. Our mentorship panel has evolved as some faculty members have left and new faculty have been recruited. One external advisory board member has rotated off and been replaced by A William Blackstock MD. Facilities and resources for the program have evolved to insure even stronger support for this program since its initial funding.

描述（由申请人提供）：在本申请中，成人和小儿血液学/肿瘤学的北卡罗来纳大学（UNC）师，放射线肿瘤学系，UNC Lineberger综合癌症中心（LCCC）以及胃肠道学和肝病学和肝病学划分，以延长UNCEW临床/翻译培训（校准）的培训（Oct Transjations transpiticational transpitical transic）（这四个组件将为拟议的培训计划贡献导师和研究资源，除UNC-LCCC以外的所有组件都将贡献学者。 OCT-RTP每年将接受两名学者。 PI Norman Sharpless博士是血液学/肿瘤科的成员医学和遗传学教授，也是LCCC转化研究副总监。 Sharpless博士在鼠类模型，新型治疗，I期试验和知识产权商业化方面具有丰富的癌症研究经验。托马斯·斯汀奇科姆（Thomas Stinchcombe）博士是血液学/肿瘤学奖学金计划总监，他刚担任了计划主任的角色。该计划的目标是建立一个有积极进取和严格训练的医师临床研究人员的干部，他们在寻求研究支持并将成为成功的，独立的患者癌症研究人员方面具有竞争力。将为OCT-RTP提供的培训资源包括：Lineberger综合癌症中心，北卡罗来纳州癌症医院，UNC医学学院K30临床研究课程以及有关种族文化和健康成果的UNC计划。 OCT-RTP的目标是提高面向患者的研究的质量和数量，包括临床研究的所有阶段，尤其是涉及转化成分的阶段。拟议的培训计划的基础将是由高素质的基础科学和临床指导者的参与，并通过指导的指导活动由导师一体化小组协调。包括来自四个组成部分的每个组成部分的高级教师在内的内部咨询委员会将选择和监视学者的进度，而外部咨询委员会将每年审查该计划。自成立以来，OCT-RTP已招募了六位学者，这些学者在进度报告中详细介绍了记录。随着一些教职员工离开并招募了新的教职员工，我们的指导小组已经发展。一位外部顾问委员会成员已旋转，并由威廉·布莱克斯托克（William Blackstock）医学博士取代。该计划的设施和资源已经演变为自最初的资金以来对该计划的强大支持。