Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network

尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 母胎医学单位网络

• 批准号: 8638045
• 负责人: Suneet P Chauhan
• 金额: $ 28.72万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8638045
• 关键词: Address; African American; American College of Obstetricians and Gynecologists; Ancillary Study; Area; Authorship; Birth; Caring; Caucasians; Caucasoid Race; Certification; Child; Clinical; Clinical Research; Clinical Trials; Collaborations; Commit; Data; Data Quality; Dedications; Discipline of obstetrics; Educational workshop; Enrollment; Environment; Faculty; Funding; Future; General Hospitals; Gestational Diabetes; Goals; Health; High birth weight infant; Hispanics; Hospitals; Human Resources; Improve Access; Informatics; Institutional Review Boards; Intervention; Leadership; Letters; Location; Manuscripts; Medical center; Mission; Multi-Institutional Clinical Trial; National Children' s Study; National Institute of Child Health and Human Development; Newborn Infant; Nurses; Nursing Research; Nursing Staff; Outcome; Outpatients; Pathogenesis; Patients; Perinatal; Physicians; Pre-Eclampsia; Pregnancy; Pregnant Women; Premature Birth; Prevention; Prevention strategy; Principal Investigator; Procedures; Productivity; Publications; Qualifying; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Resources; Services; Site; Specialist; Surgeon; Teaching Hospitals; Texas; Universities; Woman; autoimmune lymphoproliferative syndrome; base; comparative effectiveness; disability; experience; falls; fetal; fetal medicine; follow-up; improved; innovation; medical complication; medical schools; member; operation; patient population; public health relevance; racial and ethnic; screening; skills; symposium; unborn child

DESCRIPTION (provided by applicant): The Maternal-Fetal Medicine Division at the University of Texas Medical School at Houston (UT-Houston) is reapplying for its third cycle of participation in the NICHD MFMU Network (initially funded 6/2001). Dr. Susan Ramin, the original PI, became OB/GYN Chair in 10/2006 and Dr. Sean Blackwell was recruited to UT-Houston to serve as PI starting in 6/2007. Dr. Blackwell brings experience within the MFMU Network (prior WSU Alternate-PI 2003-2006), innovation, and unique expertise as the PI. Importantly, he has successfully demonstrated his leadership skills during the transition by improving data quality and increasing subject recruitment/retention. The MFMU Network at UT-Houston conducts the majority of its operations at its two university-affiliated teaching hospitals: Memorial Hermann Hospital (4,800 annual deliveries) and Lyndon B. Johnson General Hospital (3,800 annual deliveries). The administrative and physician leadership at both locations have provided unobstructed access to potential subjects, high-quality research space, and a "culture of research." Collaborations with private OB/GYN physicians and UT faculty have been strengthened and resulted in _ improved access for out-patient studies. The UT-Houston MFM research infrastructure also supports other on-going NICHD multi-center studies including Pathogenesis of Preeclampsia Network, GPN Network, and the National Children's Study. This application describes the track record of recruitment and retention (including long-term follow-up), the expertise and productivity of our MFM faculty, and the scientific contributions of UT-Houston to the MFMU Network. We describe a concept study that addresses a significant health problem (gestational diabetes and fetal overgrowth), which is innovative and demonstrates our understanding of the necessary considerations and approach needed in conducting large, multi-center, clinical trials. UT-Houston has the available patient population, institutional resources, and dedication of a highly- qualified PI to contribute to the mission of the MFMU for the next cycle and beyond.

说明（由申请人提供）：德克萨斯大学休斯顿医学院 (UT-休斯顿) 的母胎医学部门正在重新申请加入 NICHD MFMU 网络的第三个周期（最初资助于 6/2001）。最初的 PI 苏珊·拉明 (Susan Ramin) 博士于 10/2006 年成为妇产科主席，肖恩·布莱克韦尔 (Sean Blackwell) 博士于 6/2007 年被招募到 UT-休斯顿，担任 PI。 Blackwell 博士作为 PI 带来了 MFMU 网络（之前为 WSU 候补 PI 2003-2006）的经验、创新和独特的专业知识。重要的是，他在过渡期间通过提高数据质量和增加受试者招募/保留成功地展示了他的领导技能。 UT-休斯顿 MFMU 网络的大部分业务在其两所大学附属教学医院进行：赫尔曼纪念医院（每年 4,800 例分娩）和林登 B. 约翰逊综合医院（每年 3,800 例分娩）。两个地点的行政和医生领导提供了畅通无阻的接触潜在受试者的机会、高质量的研究空间和“研究文化”。与私人妇产科医生和德克萨斯大学教职人员的合作得到了加强，并改善了门诊研究的机会。 UT-休斯顿 MFM 研究基础设施还支持其他正在进行的 NICHD 多中心研究，包括先兆子痫发病机制网络、GPN 网络和国家儿童研究。 该申请描述了招聘和保留的记录（包括长期随访）、我们的 MFM 教员的专业知识和生产力，以及 UT-休斯顿大学对 MFMU 网络的科学贡献。我们描述了一项解决重大健康问题（妊娠糖尿病和胎儿过度生长）的概念研究，该研究具有创新性，表明我们对进行大型多中心临床试验所需的必要考虑因素和方法的理解。 UT-休斯顿大学拥有可用的患者群体、机构资源和高素质 PI 的奉献精神，可以为 MFMU 下一个周期及以后的使命做出贡献。