Admin-Core

管理核心

基本信息

批准号：
10241466
负责人：
SUSAN L. FURTH
金额：
$ 28.22万
依托单位：
CHILDREN'S HOSP OF PHILADELPHIA
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-18 至 2022-09-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10241466
关键词：
Basic Science Biomedical Research Child Childhood Clinical Research Clinical Trials Communities Development Direct Costs Effectiveness Evaluation Feasibility Studies Funding Goals Health system Human Subject Research Individual Institution Kidney Kidney Diseases Knowledge Learning Logistics Methods National Institute of Diabetes and Digestive and Kidney Diseases Nephrology Observational Study Outcome Pediatric Hospitals Pennsylvania Philadelphia Pilot Projects Productivity Quality of life Records Research Research Methodology Research Personnel Research Project Grants Research Training Risk Factors Services Structure Talents Therapeutic Training Translational Research Universities Vulnerable Populations base bone health clinical phenotype design improved medical schools meetings member nutrition programs research data dissemination skills web site

项目摘要

ADMINISTRATION CORE ABSTRACT The Pediatric Centers of Excellence in Nephrology funded by the NIDDK provide a focus to increase efficiency and promote collaborative efforts among groups of successful investigators at institutions with established comprehensive kidney research bases. We propose an administrative structure for the Children’s Hospital of Philadelphia (CHOP) Pediatric Center of Excellence in Nephrology that will form an interdisciplinary partnership between colleagues with expertise in design and analysis of observational studies and clinical trials, with individuals successful in initiating pediatric clinical trials within learning health systems, and colleagues with proven track records in research methods, clinical phenotyping and research training. The CHOP-PCEN will have three biomedical research cores in addition to the Administrative core; a Design and Analysis core, a Clinical phenotyping core focused on Nutrition/CVD risk factors and Bone health, and a Learning Health System Core, as well as a pilot and feasibility program, an enrichment core and two research project proposals utilizing the cores. The overall goal of the administrative core is to provide direction, guidance and oversight for the entire PCEN and assure its effective and efficient functioning. The Administrative core will interact with and engage our research base which includes 39 investigators, with 150 funded projects totaling over $35 million in annual direct costs. Over $12 million of this funding is directly relevant to pediatric nephrology led by likely users of the core services.

管理核心摘要由 NIDDK 资助的儿科肾病卓越中心重点关注提高效率并促进成功研究人员群体之间的协作努力在已建立综合肾脏研究基地的机构中，我们提出了一个建议。费城儿童医院 (CHOP) 儿科中心的行政结构肾脏病学的卓越成就将在同事之间形成跨学科合作伙伴关系与个人一起设计和分析观察性研究和临床试验的专业知识成功地在学习卫生系统内启动了儿科临床试验，以及在研究方法、临床表型和研究培训方面拥有良好的记录。除行政核心外，CHOP-PCEN 将拥有三个生物医学研究核心；设计和分析核心，专注于营养/CVD 风险因素和骨骼健康、学习健康系统核心、以及试点和可行性计划、浓缩核心和利用核心的两个研究项目提案。行政核心是为整个 PCEN 提供指导、指导和监督确保其有效和高效的运作。参与我们的研究基地，其中包括 39 名研究人员，资助项目总计 150 个每年超过 3500 万美元的直接费用中有超过 1200 万美元与直接相关。由核心服务的可能用户领导的儿科肾脏病学。