NIDCR DIR Production Facilities

NIDCR DIR 生产设施

• 批准号: 8149654
• 负责人: Kathryn Carbone
• 金额: $ 16.58万
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8149654
• 关键词: Disease; National Institute of Allergy and Infectious Disease; National Institute of Dental and Craniofacial Research; Production

Recognizing the need for innovative cell therapies, NIDCR leadership was instrumental in gaining support and raising funding for the establishment of a trans-NIH Bone Marrow Stromal Cell Transplantation Center. This Center arose from a proposal that was selected by a number of Institute Directors who issued a call for proposals that stimulate new activity in the new NIH Clinical Center. The Center was established on October 1st, 2008 by NIDCR, NCI, NIAID, NINDS, NIAMS, NIBIB and the CC. The mission of the Center is to establish the procedures for preparation of clinical grade human bone marrow stromal cells, which have been found to ameliorate a number injuries and conditions due to their trophic effect on local stem/progenitor cells. The Centers funding is for building of the infrastructure within the Cell Processing Laboratory in the Department of Transfusion Medicine to ex vivo expand the cells and still retain their biological activity. The Center has made a great deal of progress during the past 11 months.

认识到对创新细胞疗法的需求，NIDCR 领导层在获得支持和筹集资金以建立跨 NIH 骨髓基质细胞移植中心方面发挥了重要作用。 该中心源于一项由多位研究所所长选出的提案，他们呼吁提出提案，以刺激新的 NIH 临床中心的新活动。 该中心于2008年10月1日由NIDCR、NCI、NIAID、NINDS、NIAMS、NIBIB和CC成立。 该中心的使命是建立临床级人骨髓基质细胞的制备程序，由于其对局部干/祖细胞的营养作用，已发现这些细胞可以改善许多损伤和病症。 该中心的资金用于在输血医学系的细胞处理实验室内建设基础设施，以离体扩增细胞并仍保留其生物活性。 在过去 11 个月中，该中心取得了很大进展。