Core 1: Adaptation, Dissemination, and Implementation Shared Resource Core

核心 1：改编、传播和实施共享资源核心

• 批准号: 10247786
• 负责人: LAURA Q ROGERS
• 金额: $ 14.72万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10247786
• 关键词: Action Research; Address; Algorithms; Behavior Therapy; Body Weight; Cancer Intervention; Cancer Survivor; Cancer Survivorship; Communities; Computer software; Consolidated Framework for Implementation Research; Consult; Data; Data Analyses; Data Collection; Diffusion of Innovation; Dissemination and Implementation; Elements; Ensure; Evaluation; Exercise; Future; Geographic Locations; Health; Health Benefit; Health behavior; Individual; Informatics; Infrastructure; Intervention; Knowledge; Logistics; Malignant Neoplasms; Measurement; Measures; Methodology; Methods; Minority; Minority Groups; Modeling; Older Population; Outcome; Physical activity; Population; Process; Production; Quality of life; Randomized Controlled Trials; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Recommendation; Research; Research Methodology; Research Personnel; Resource Sharing; Resources; Rural; Rural Population; Science; Subgroup; Technology; Testing; Time; Training; Translating; Translational Research; Translations; Treatment Efficacy; Weight maintenance regimen; behavior change; cancer diagnosis; cancer therapy; dissemination strategy; efficacy evaluation; efficacy testing; health disparity; implementation barriers; implementation facilitators; implementation intervention; implementation outcomes; implementation process; implementation science; implementation strategy; improved; innovation; multidisciplinary; rural dwellers; success; theories

The overall objective of the AMPLIFI Adaptation, Dissemination, and Implementation (ADI) Shared Resource Core (SRC) is to provide all AMPLIFI projects with the expertise and infrastructure required for intervention adaptation, optimizing future dissemination and implementation (D&I), and identifying processes common across all interventions that advance adaptation and D&I science. Although multiple randomized controlled trials have tested the efficacy of interventions aimed at improving health behaviors after a cancer diagnosis and treatment, translation of these interventions into standard practice and broader use is limited. Such translation could be improved by developing an integrated approach to intervention adaptation to different settings, subgroups, and distance-delivery strategies while improving intervention D&I potential. Mixed methods research approach is well-recognized as crucial to the adaptation process and provides the rich data needed to better understand adaptation and D&I strategies. Hence, the ADI SRC includes a multidisciplinary team with collective expertise in adaptation, D&I science, mixed methods research, cancer survivorship, older, rural and minority populations, technology-supported health behavior interventions, and health disparities. In so doing, the ADI SRC will support all AMPLIFI projects and fill an important scientific knowledge gap related to the “type 3 evidence” needed to better adapt and implement interventions. The ADI SRC specific aims are: Primary Aim: Support each project by developing and maintaining an infrastructure for providing methodological guidance, expert consulting and trained staff to ensure that investigators have ready access to relevant resources, mixed methods data, and logistical support for measuring D&I related outcomes, completing intervention adaptations, evaluation, and refinements, and finalizing implementation toolkits. Secondary Aim 1: Assist project investigators in describing, categorizing, and tallying adaptations required by each project (before and during implementation) to determine the most common adaptations needed for different cancer groups, geographical locations, and distance delivery methods. Secondary Aim 2: Assist project investigators in optimizing intervention D&I after project completion. This will include but is not limited to identifying similarities and differences across the project interventions to optimize D&I after project completion (e.g., D&I barriers and facilitators, relevant stakeholders and community partners, and potential strategies and venues for improving future D&I of the adapted interventions). Secondary Aim 3: Develop an adaptation model for guiding adaptations of health behavior interventions for cancer survivors applicable across different health behaviors and types of distance-delivery methods. The D&I outcomes data will be used to integrate recommendations for improving D&I potential into the model. The ADI SRC's exceptional team of investigators and consultants will use a rigorous mixed methods approach to optimize all AMPLIFI projects and innovatively integrate cross-project data to advance D&I science.

AMPLIFI 适应、传播和实施 (ADI) 共享资源的总体目标 核心（SRC）是为所有 AMPLIFI 项目提供干预所需的专业知识和基础设施 适应、优化未来的传播和实施 (D&I) 以及确定通用流程 跨越所有促进适应和 D&I 科学的干预措施，尽管是多重随机对照的。 试验测试了旨在改善癌症诊断后健康行为的干预措施的有效性 和治疗，将这些干预措施转化为标准实践和更广泛的使用是有限的。 可以通过制定针对不同情况的干预措施的综合方法来改进翻译 环境、亚组和远程交付策略，同时提高干预 D&I 潜力。 方法 研究方法被公认为对适应过程至关重要，并提供了丰富的数据 因此，ADI SRC 包括一个多学科的团队。 团队在适应、D&I 科学、混合方法研究、癌症生存、老年、 农村和少数民族人口、技术支持的健康行为干预措施以及健康差异。 ADI SRC 将支持所有 AMPLIFI 项目，并填补与以下领域相关的重要科学知识空白： 更好地适应和实施干预措施所需的“3 类证据”是： 主要目标：通过开发和维护基础设施来支持每个项目 方法指导、专家咨询和训练有素的工作人员，以确保调查人员能够随时获取 用于衡量 D&I 相关成果的相关资源、混合方法数据和后勤支持， 干预完成调整、评估和完善，并最终确定实施工具包。 次要目标 1：协助项目调查人员描述、分类和统计所需的调整 每个项目（在实施之前和实施期间）确定最常见的调整所需 不同的癌症组、地理位置和距离输送方法。 次要目标 2：协助项目研究人员在项目完成后优化干预 D&I。 将包括但不限于识别项目干预措施的相似点和差异 项目完成后优化 D&I（例如 D&I 障碍和促进者、相关利益相关者和社区 合作伙伴，以及改进适应干预措施的未来 D&I 的潜在策略和场所）。 次要目标 3：开发适应模型，指导健康行为干预措施的调整 癌症幸存者适用于不同的健康行为和远程交付方法类型。 D&I 结果数据将用于将提高 D&I 潜力的建议整合到模型中。 ADI SRC 杰出的调查员和顾问团队将采用严格的混合方法 优化所有 AMPLIFI 项目并创新性地集成跨项目数据，以推进 D&I 科学。