Novel Ca receptor signaling pathways for control of renal ion transport

控制肾离子转运的新型 Ca 受体信号通路

• 批准号: 8195579
• 负责人: Richard Tyler Miller
• 金额: --
• 依托单位: LOUIS STOKES CLEVELAND VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195579
• 关键词: Affect; Bartter Disease; Bicarbonates; Biochemical; Biotinylation; Blood; Blood Pressure; Body Fluids; Calcium; Calcium-Sensing Receptors; Cardiovascular system; Carrier Proteins; Cell Communication; Cell surface; Cells; Characteristics; Cloning; Complications of Diabetes Mellitus; Coupled; Cultured Cells; Data; Disease; Distal; Dominant-Negative Mutation; Edema; Enzymes; Epithelial Cells; Family; G-Protein-Coupled Receptors; GTP-Binding Proteins; Goals; Health; Heart Diseases; Hematological Disease; Hereditary Disease; Heterotrimeric GTP-Binding Proteins; Hypercalcemia; Hypertension; Hypotension; Intracellular Second Messenger; Ion Transport; Ions; Kidney; Kidney Diseases; Lead; Location; MDCK cell; Measurement; Measures; Membrane; Membrane Transport Proteins; Minor; Modeling; Mutation; Nephrons; Pathologic; Pathway interactions; Patients; Phenotype; Phosphoproteins; Phosphotransferases; Physiological; Population; Potassium Channel; Process; Proteins; Receptor Activation; Receptor Signaling; Regulation; Renal Glycosuria; Risk Factors; Running; Scaffolding Protein; Second Messenger Systems; Signal Pathway; Signal Transduction; Signaling Protein; Small Interfering RNA; Sodium Chloride; Stroke; Surface; System; Testing; Two-Hybrid System Techniques; Urine; Variant; Vascular Diseases; Veterans; Water; Xenopus oocyte; Yeasts; adverse outcome; apical membrane; base; basolateral membrane; blood pressure regulation; body volume; clinically significant; density; extracellular; improved; in vivo; inward rectifier potassium channel; kidney cell; loss of function mutation; monolayer; mutant; novel; protein transport; receptor; research study; response; yeast two hybrid system