Targeting the COX-2 Pathway to Reduce Breast Cancer Mortality

针对 COX-2 通路降低乳腺癌死亡率

• 批准号: 7789458
• 负责人: Amy M. Fulton
• 金额: --
• 依托单位: BALTIMORE VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7789458
• 关键词: Affect; African American; Age; Aggressive behavior; Aging; American; Apoptosis; Behavior; Binding; Biological; Biology; Breast; Breast Adenocarcinoma; Cardiotoxicity; Cell Nucleus; Cell membrane; Chronic; Clinical; Collection; Colon; Complex; Coupled; Cyclooxygenase Inhibitors; Data; Death Rate; Diagnosis; Dinoprostone; Disease; Disease Progression; Distant; EP4 receptor; Effector Cell; Enzyme Inhibition; Enzyme Inhibitor Drugs; Enzyme Inhibitors; Enzymes; Epidemiologic Studies; Equilibrium; European; Female; G-Protein-Coupled Receptors; Gene Expression Profile; Genetic; Goals; Health Services Accessibility; Healthcare; Immune; Incidence; Laboratories; Ligands; Location; Malignant - descriptor; Malignant Neoplasms; Mammary Neoplasms; Mediating; Metastasis Suppressor Genes; Metastatic to; Mission; Modeling; Mus; Natural Killer Cells; Neoplasm Metastasis; Newly Diagnosed; Outcome; Patient Care; Pattern; Play; Population; Pre-Clinical Model; Prostaglandin E Receptor; Prostate; Puerto Rico; Risk; Role; Signal Pathway; Signal Transduction; Social Impacts; Solid; Specimen; Staging; Stream; T-Lymphocyte; Testing; Therapeutic Intervention; Tumor Angiogenesis; Up-Regulation; Veterans; Woman; Work; aging population; cancer health disparity; cyclooxygenase 2; economic impact; enzyme activity; enzyme pathway; human WFDC2 protein; improved; malignant breast neoplasm; mortality; neoplastic cell; novel strategies; outcome forecast; overexpression; prevent; prognostic indicator; prostaglandin EP4 receptor; prostanoid receptor EP1; public health relevance; racial difference; receptor; receptor binding; receptor expression; receptor function; success; tumor; tumor growth; tumor progression