Mechanisms of Renal Lipotoxicity and Injury in Obesity and Diabetes

肥胖和糖尿病肾脂毒性和损伤的机制

• 批准号: 7780064
• 负责人: Jesus H. Dominguez
• 金额: --
• 依托单位: RLR VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7780064
• 关键词: Abdomen; Accounting; Address; Adherence; Adipocytes; Albumins; Apoptosis; Appearance; Attention; Binding; Blood capillaries; Cells; Clinical; Consumption; Diabetes Mellitus; Diet; Dietary Fats; Dietary Fatty Acid; Dyslipidemias; Epidemiologic Studies; Epithelial; Epithelial Cells; Fatty Acids; Fatty acid glycerol esters; Fibrosis; Focal Adhesion Kinase 1; Functional disorder; Glomerular Capillary; Hyperglycemia; Hypertension; In Vitro; Inflammation; Inflammatory; Inflammatory Response; Ingestion; Injury; Insulin Resistance; Intercellular adhesion molecule 1; Interstitial Nephritis; Kidney; Kidney Diseases; Kidney Failure; LOX gene; Lead; Leukocytes; Link; Lipid Peroxides; Lipids; Lipoproteins; Liver; Low Density Lipoprotein Receptor; Low-Density Lipoproteins; Mediator of activation protein; Metabolic syndrome; Nonesterified Fatty Acids; Obesity; Organ; Paper; Permeability; Phenotype; Play; Population; Progress Reports; Proteinuria; Proximal Kidney Tubules; Publications; Rattus; Relative (related person); Renal Glycosuria; Renal tubule structure; Reporting; Risk Factors; Role; Saturated Fatty Acids; Series; Serum; Side; Source; System; Testing; Toxic effect; Tubular formation; Unsaturated Fatty Acids; Urine; Veterans; Visceral; base; capillary; cell injury; chemokine; cytotoxic; diabetic; diabetic rat; feeding; in vivo; interstitial; macromolecule; mouse model; novel; oxidized lipid; oxidized low density lipoprotein; public health relevance; receptor; response; uptake; urinary