University of Cincinnati NETT Network Hub and Spoke System

辛辛那提大学 NTT 网络中心辐射系统

• 批准号: 8856668
• 负责人: Opeolu M Adeoye
• 金额: $ 30.02万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8856668
• 关键词: Acute; Acute Disease; Advisory Committees; Affect; Caring; Chairperson; Characteristics; Clinical; Clinical Research; Clinical Trials; Committee Members; Communication; Communities; Complex; Conduct Clinical Trials; Continuity of Patient Care; Data; Data Quality; Disclosure; Disease; Effectiveness; Electronics; Eligibility Determination; Emergency Department Physician; Emergency Situation; Emergency treatment; Enrollment; Environment; Ethics; Failure; Funding; Goals; Health; Health system; Hospitals; Human Resources; Injury; Institutional Review Boards; Kentucky; Learning; Medicine; Monitor; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurologist; Neurology; Neurosurgeon; Nurses; Outcome; Participant; Patient Recruitments; Patients; Persons; Physician Executives; Population; Positioning Attribute; Process; Protocols documentation; Provider; Randomized; Recruitment Activity; Rehabilitation therapy; Reporting; Request for Applications; Research; Research Design; Research Infrastructure; Research Personnel; Resolution; Site; Summary Reports; Symptoms; System; Training; Trauma; Universities; base; clinical research site; college; community consultation; data management; design; experience; flexibility; implementation trial; improved; meetings; multidisciplinary; nervous system disorder; neurosurgery; operation; patient population; screening; success; treatment trial; willingness; working group

DESCRIPTION (provided by applicant): The Neurological Emergencies Treatment Trials (NETT) Network has successfully established a clinical research network including emergency physicians, neurologists and neurosurgeons. The network's goals are to efficiently develop better treatments for patients with acute neurological disorders through execution of NINDS-sponsored clinical trials (RFA-NS-06-002). The essential aim of the NETT Network is to expedite recruitment into clinical trials. The Greater Cincinnati/Northern Kentucky NETT Hub and Spoke System was one of seventeen original Clinical Site Hubs funded under the 2006 Request for Applications. To date, our Cincinnati NETT Hub and Spoke System has enrolled over 226 patients in trials being conducted through the NETT Network. This positions us as the 2nd highest enroller among NETT Hubs. In this renewal application, we build on the success of our existing Hub and Spoke System with the following specific aims: #1) Efficiently recruit and retain participants and optimize data quality in NETT trials; and, #2) Actively contribute to the overall success of the NETT Network. To achieve these aims, we have identified four key ingredients that contribute to our continued success. These include: strong and ongoing institutional and community support; access to a demographic representative of the populations to which results must be generalized; unfiltered access to the full spectrum of acute neurologic disease and injury; and, active participation in and contributory to the efforts of the NETT Network. In this competitive renewal application, we demonstrate the strong and unwavering support of key players at our Hub including the Dean of the College of Medicine and the CEO of our Hub hospital. Further, we show a strong, multidisciplinary commitment to the success of our Hub and Spoke System embodied in our Advisory Committee members which include the Chairmen of Neurology and Neurosurgery, the PI of our CTSA, the Director of the Division of Trauma, and the COO of a large health system in Greater Cincinnati whose purview includes five of our Spoke hospitals. In addition to the high level support we receive from Institutional an community leaders, we demonstrate our ability to access the appropriate patient populations by presenting data on the relevant disease processes and showing the unyielding support we have from 'boots-on-the-ground' personnel from Medical Directors to bedside nurses. We have and will continue to be actively engaged in all NETT Network activities in order to learn how we may continue to optimize our Hub and Spoke System while also sharing our experience in ways that may be beneficial to other Hubs.

描述（由申请人提供）：神经系统紧急治疗试验（NETT）网络已成功建立了一个临床研究网络，包括急诊医师，神经病学家和神经外科医生。该网络的目标是通过执行NINDS赞助的临床试验（RFA-NS-06-002）有效地为患有急性神经系统疾病的患者开发更好的治疗方法。 NetT网络的基本目的是加快招募临床试验。辛辛那提/北部北肯塔基州净纳特枢纽和辐条系统是根据2006年申请要求资助的17个原始临床站点中心之一。迄今为止，我们的辛辛那提Nett Hub和Skok System已招募了226名患者通过NetT网络进行试验。这将我们定位为NetT中心中第二高的入学者。在此续订应用程序中，我们基于现有枢纽的成功并以以下特定目的进行了交谈系统：＃1）有效招募和保留参与者并在Nett试验中优化数据质量；并且，＃2）积极地为NetT网络的整体成功做出了贡献。 为了实现这些目标，我们已经确定了有助于我们持续成功的四种关键要素。 其中包括：强大而持续的机构和社区支持；访问必须推广结果的人群代表；未经过滤的急性神经系统疾病和损伤的范围未过滤；并且，积极参与NetT网络的努力并贡献了这一点。在此竞争性更新应用程序中，我们证明了我们枢纽中主要参与者的强烈而坚定不移的支持，包括医学院院长和我们枢纽医院的首席执行官。此外，我们对咨询委员会成员的枢纽和讲话系统的成功表现出了强烈的多学科承诺，其中包括神经病学和神经外科主席，我们的CTSA的PI，创伤部门的PI，创伤部门主任，以及大型辛辛那提大型卫生系统的大型卫生系统的COO，包括我们的Speckinnati purview的五个人的spehtals。除了我们从机构的社区领导者那里获得的高水平支持外，我们还证明了我们通过提供有关相关疾病过程的数据来获得适当患者人群的能力，并向我们展示了我们从医疗董事到床层护士的“地面”人员的不屈不挠的支持。我们已经并且将继续积极参与所有NetT网络活动，以了解我们如何继续优化轮毂和讲话系统，同时还以可能对其他枢纽有益的方式分享我们的经验。