2015 RNA Nanotechnology Gordon Research Conference

2015年RNA纳米技术戈登研究会议

基本信息

批准号：
8831228
负责人：
PEIXUAN GUO
金额：
$ 2.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-01-15 至 2016-01-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8831228
关键词：
Academia Address Advertising Amaze Antibodies Area Attention Base Pairing Basic Science Binding Biochemical Biochemistry Biocompatible Materials Bioinformatics Biological Markers Biological Sciences Biophysics Cancer Biology Cellular biology Chemicals Chemistry Clinical Investigator Code Collaborations Communities Construction Materials DNA Development Discipline Disease Disease Pathway Disease Progression Drug Industry Drug Targeting Early Diagnosis Engineering Eye diseases Fostering Free Energy Funding Future Genome Goals Government Growth Health Human Genome Imaging technology Immunology Individual Junk DNA Knowledge Malignant Neoplasms Microbiology Modality Modeling Monitor Nanostructures Nanotechnology Nature Pharmaceutical Preparations Pharmacologic Substance Postdoctoral Fellow Principal Investigator Private Sector Property Proteins Public Sector RNA RNA Computations RNA Folding RNA Processing Rare Diseases Reporting Research Research Personnel Schedule Science Scientist Staging Structure Technology Therapeutic Translating Translational Research Untranslated RNA Virus Diseases Woman Work base career clinical application design disease diagnosis extracellular flexibility fundamental research graduate student image guided improved in vivo meetings nanomedicine nanoparticle nanosensors nanotherapeutic non-invasive imaging novel programs public health relevance research clinical testing single molecule stoichiometry structural biology symposium therapeutic development undergraduate student

项目摘要

DESCRIPTION (provided by applicant): The goal of this R13 application is to request partial funding support for the upcoming Gordon Research Conference (GRC) on RNA Nanotechnology, scheduled to be held Feb 1-6, 2015 in Ventura, CA. This meeting will be chaired by Peixuan Guo, who pioneered the field of RNA Nanotechnology. Neocles Leontis with extensive expertise in RNA structure and RNA bioinformatics will serve as the vice-chair. Over the last five years, RNA nanotechnology has attracted widespread attention and has become a vigorous and rapidly emerging new field of science (Guo P. Nature Nanotechnology, 2010, 5:833). RNA nanotechnology exploits the modularity and designability of RNA folding and assembly at multiple structural levels to rationally design and functionalize RNA nanoparticles for diverse applications in nanotechnology and nanomedicine. This GRC is geared towards the applications of RNA nanoparticles for early disease diagnosis; non-invasive imaging to monitor the progression of diseases; and targeting and treatment of a wide range of diseases from cancer, bacterial, viral infections to rare eye diseases. The specific aim of this conference is t provide a forum for advancing this new field from discovery to clinical evaluations. Accordingly, researchers from public and private sectors will be invited to: (1) share existing knowledge and set future research initiatives in the field; and (2) foster collaborations between physical/engineering scientists with life sciences researchers, and basic science researchers with clinical investigators. The meeting will cover a range of topics, including biophysical and single molecule approaches for characterization of RNA nanostructures; structural and functional studies on RNA nanoparticles by chemical or biochemical approaches; computation, prediction, and modeling of RNA nanoparticle structures focusing on inter-molecular interactions; application of RNA nanoparticles in therapeutics for the treatment of diseases; and finally two sessions covering the exciting new area of extracellular RNA for biomarker and therapeutic development. The invited speakers and discussion leaders for this GRC will include a mix of world-renowned researchers in the field as well as exceptional junior-level investigators from around the world. The meeting will be advertised to a diverse audience to include early career (undergraduate/graduate students and postdocs) and under-represented scientists in the field.

描述（由应用程序提供）：此R13申请的目标是为即将举行的有关RNA纳米技术的戈登研究会议（GRC）提供部分资金支持，该学计划于2015年2月1日至6日在加利福尼亚州的文图拉举行。这次会议将由Peixuan Guo主持，后者开创了RNA纳米技术领域。 Neocles Leontis在RNA结构和RNA生物信息学方面具有广泛的专业知识，将作为副主席。在过去的五年中，RNA纳米技术引起了广泛的关注，并已成为一个充满活力，迅速发展的新科学领域（Guo P. Nature Nanotechnology，2010，5：833）。 RNA纳米技术探讨了在多个结构水平上的RNA折叠和组装的模块化和设计，以合理设计并使RNA纳米颗粒在纳米技术和纳米医学中的潜水应用中官能化。该GRC针对RNA纳米颗粒在早期疾病诊断中的应用；非侵入性成像以监测疾病的进展；以及从癌症，细菌，病毒感染到罕见眼部疾病的广泛疾病的靶向和治疗。本次会议的具体目的是提供一个论坛，可以将这个新领域从发现到临床评估。据公共部门和私营部门的研究人员将被邀请：（1）在该领域共享现有知识并设定未来的研究计划；（2）培养物理/工程科学家与生命科学研究人员与基础科学研究人员与临床研究人员之间的合作。会议将涵盖一系列主题，包括用于表征RNA纳米结构的生物物理和单分子方法；通过化学或生化方法对RNA纳米颗粒的结构和功能研究； RNA纳米颗粒结构的计算，预测和建模，重点是分子间相互作用； RNA纳米颗粒在治疗疾病治疗中的应用；最后，两次会议涵盖了用于生物标志物和治疗发育的细胞外RNA的令人兴奋的新领域。该GRC的受邀演讲者和讨论领袖将包括该领域享誉世界的研究人员以及来自世界各地的杰出初级研究人员。会议将向潜水员的听众广告，以包括早期职业（本科/研究生和博士后）和该领域代表性不足的科学家。