Role of NGF in inflammatory and proliferative cascades of psoriatic disease

NGF 在银屑病炎症和增殖级联反应中的作用

• 批准号: 7782757
• 负责人: SIBA P RAYCHAUDHURI
• 金额: --
• 依托单位: VA NORTHERN CALIFORNIA HEALTH CARE SYS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2012-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7782757
• 关键词: Affinity; American; Anesthesia procedures; Animal Experiments; Ankle; Antibodies; Apoptosis; Apoptotic; Arthritis; Asthma; Atopic Dermatitis; Autoimmune Process; Autologous; Blood; Blood Cells; Body part; CD8-Positive T-Lymphocytes; CD8B1 gene; Cell Culture Techniques; Cell Line; Cells; Cellular biology; Characteristics; Chemicals; Chronic; Clinical; Cutaneous; Cutaneous Involvement; Data; Degenerative polyarthritis; Dimensions; Discipline; Disease; Embryo; Endothelial Cells; Epidermis; Etiology; Event; Eye; Fibroblasts; Functional disorder; Gastrointestinal tract structure; Goals; Hand; Homing; Human; Human body; Immune; Immune system; In Situ Hybridization; In Vitro; Inflammation; Inflammatory; Injection of therapeutic agent; Intralesional Injections; Joints; K 252a; Knee; Language; Lesion; Leucocytic infiltrate; Life; Liquid substance; Lymphocyte Subset; Maintenance; Medicine; Modeling; Morbidity - disease rate; Mus; Musculoskeletal System; NF-kappa B; Nerve; Nerve Growth Factors; Neurogenic Inflammation; Neuropeptides; Neurotrophic Tyrosine Kinase Receptor Type 1; Organ; Pain; Pathogenesis; Pathologic; Patient Care; Patients; Peripheral Blood Mononuclear Cell; Pilot Projects; Play; Population; Process; Psoriasis; Psoriatic Arthritis; Reaction; Research; Research Personnel; Research Project Grants; Residual state; Rheumatoid Arthritis; Role; SCID Mice; Signal Transduction; Site; Skin; Skin Transplantation; Skin graft; Social Impacts; Source; Synovial Cell; Synovial Fluid; Synovial Membrane; System; T memory cell; T-Cell Activation; T-Lymphocyte; Tail; Tissues; Transplantation; Tropism; Up-Regulation; Veins; Vertebral column; Work; Wrist; Xenograft Model; Xenograft procedure; angiogenesis; chemokine; cytokine; economic impact; foot; improved; in vivo; inhibitor/antagonist; intradermal injection; intravenous injection; joint injury; keratinocyte; neutralizing antibody; neutrophil; novel therapeutic intervention; patient population; public health relevance; receptor; research study; skin disorder; skin xenograft; success; trafficking; transcriptional coactivator p75