Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins

人内皮缺血/再灌注损伤：葡萄糖和他汀类药物的作用

• 批准号: 7916711
• 负责人: Thomas Jay Ebert
• 金额: --
• 依托单位: CLEMENT J. ZABLOCKI VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7916711
• 关键词: Acetylcholine; Adverse effects; Anesthetic Gases; Anesthetics; Animal Model; Animals; Appearance; Area; Ascorbic Acid; Blood; Blood Circulation; Blood Glucose; Blood Vessels; Blood flow; Brain; Cardiac Surgery procedures; Cell Death; Characteristics; Cholesterol; Clinical; Data; Diabetes Mellitus; Disease; Dose; Endothelial Cells; Endothelium; Event; Experimental Animal Model; Exposure to; Forearm; Functional disorder; General Population; Generations; Glucose; Grant; Heart Injuries; Hour; Human; Hyperglycemia; Inflammatory; Inflammatory Response; Infusion procedures; Injury; Interruption; Ischemia; Ischemic Preconditioning; Kidney; Knowledge; Measures; Methods; Modeling; Morbidity - disease rate; Myocardial; Myocardium; Necrosis; Neutrophil Activation; Nitric Oxide; Nitric Oxide Pathway; Nitric Oxide Synthase; Organ; Outcome; Oxidoreductase; Oxygen; Pathway interactions; Patients; Pharmaceutical Preparations; Play; Plethysmography; Reactive Oxygen Species; Reperfusion Injury; Reperfusion Therapy; Research; Risk; Role; Simvastatin; Spinal Cord; Stimulus; Stress; Stroke; Time; Tissues; Vascular Endothelium; Vasomotor; Venous; Work; abstracting; adverse outcome; brachial artery; cytokine; diabetic patient; glutaryl coA; human data; human tissue; improved; in vivo; inhibitor/antagonist; insight; interest; mortality; omega-N-Methylarginine; preconditioning; protective effect; public health relevance; sevoflurane; species difference