Core 2: Methodology

核心 2：方法论

• 批准号: 10079947
• 负责人: Sean M. Murphy
• 金额: $ 25.8万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10079947
• 关键词: Accounting; Address; Adoption; Alcohol or Other Drugs use; Applications Grants; Area; Caring; Chronic Disease; Clinical; Collaborations; Communities; Consultations; Cost Savings; Cost-Benefit Analysis; Costs and Benefits; Data; Data Set; Development; Disease; Doctor of Philosophy; Economic Policy; Economics; Effectiveness; Ensure; Equilibrium; Evaluation Methodology; Evidence based practice; Evidence based treatment; Goals; HIV; HIV/HCV; Health; Health Services Research; Hepatitis C virus; Individual; Interdisciplinary Study; Intervention; Life Expectancy; Link; Measures; Methodology; Methods; Modeling; Outcome; Outcomes Research; Play; Policies; Policy Maker; Population; Procedures; Productivity; Protocols documentation; Provider; Qualifying; Quality of life; Records; Recovery; Research; Research Personnel; Research Support; Resource Allocation; Resources; Role; Schools; Services; Substance Use Disorder; System; Time; Treatment Cost; Update; Work; adaptive intervention; budget impact; comparison intervention; cost; cost effectiveness; cost outcomes; design; economic evaluation; economic impact; evidence base; health economics; implementation research; implementation science; improved; individual patient; intervention cost; multidisciplinary; novel strategies; online community; programs; sound; therapy development; tool; treatment program; uptake

PROJECT SUMMARY: Methodology Core This Core focuses on economic evaluation approaches, tools, and measures to support new and existing interdisciplinary research collaborations. Despite decades of research supporting a chronic disease approach to substance use disorder treatment and recovery, uptake and sustainment remain low. Some of the most important factors inhibiting adoption of evidence-based practices are concerns about the potential burden on staff and other resources, as well as overall budget impact. Changing current practices requires not only clinical evidence, but also consideration of additional costs and the reallocation of existing resources that will result from the changes. Economic analysis can directly address these issues by providing a detailed accounting of the costs to the provider of updating services, and more broadly inform “real-world” resource allocation decisions by providing policymakers and payers with evidence on the net economic and health impact of new approaches and their fiscal viability over time. This requires considering both costs and consequences of a new intervention, often using a cost-effectiveness or cost-benefit analysis framework. The overall aim of CHERISH (Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV) is to develop and disseminate economic evidence that informs substance use disorder policy and HCV and HIV care of people who use substances. In this renewal period we will expand our focus to outcome and implementation research that is conducted at the individual, system, and community levels with the following specific aims: 1) to guide researchers in the design, implementation, and interpretation of economic analyses of treatment for substance use disorder, and HCV and HIV among people who use substances, and 2) to develop and apply methods that support economic evaluations for substance use disorder, and HCV and HIV among people who use substances with a focus on intervention implementation and adaptive interventions. Through the CHERISH Consultation Service and Research Affiliates Program, we will contribute to the development of new grant proposals with explicit economic aims, and will continue to connect with and advise qualifying researchers nationally to ensure that planned economic analyses are methodologically sound and feasible. We will expand the CHERISH Research Affiliates program so it can serve as a nationally-representative virtual community for researchers engaged in substance use disorder treatment health economic research. Working with existing studies and integrating data from third-party datasets and administrative records, we will develop analytic frameworks and tools for evaluating individual and systems-level substance use disorder and related implementation interventions. We will also develop economic evaluation methods for adaptive interventions. In collaboration with the Population Data & Modeling Core, we will assist researchers in using external data to enhance interpretation of economic evaluation results.

项目摘要：方法论核心 该核心重点关注经济评估方法、工具和措施，以支持新的和现有的 尽管数十年的研究支持慢性病方法。 物质使用障碍的治疗和恢复、吸收和维持率仍然很低。 阻碍采用循证实践的重要因素是对潜在负担的担忧 改变当前的做法不仅需要人员和其他资源以及总体预算影响。 临床证据，还考虑额外成本和现有资源的重新分配，这将 经济分析可以通过提供详细的结果来直接解决这些问题。 计算更新服务提供商的成本，并更广泛地告知“现实世界”资源 通过向政策制定者和付款人提供有关净经济和健康的证据来做出分配决策 新方法的影响及其随着时间的推移的财政可行性，这需要考虑成本和成本。 新干预措施的后果，通常使用成本效益或成本效益分析框架。 CHERISH（物质使用障碍治疗干预措施健康经济学中心， HCV 和 HIV）旨在开发和传播为药物滥用障碍政策提供信息的经济证据 以及对使用药物的人的丙型肝炎和艾滋病毒护理。在这一更新期间，我们将把重点扩大到以下方面。 在个人、系统和社区层面进行的成果和实施研究 具体目标如下： 1）指导研究人员设计、实施和解释 对物质使用障碍以及使用者中的 HCV 和 HIV 治疗的经济分析 物质，以及 2) 开发和应用支持物质使用经济评估的方法 药物滥用者中的疾病、丙型肝炎病毒和艾滋病毒，重点是实施干预措施 通过 CHERISH 咨询服务和研究附属计划，我们 将有助于制定具有明确经济目标的新赠款提案，并将继续 与全国合格的研究人员联系并提供建议，以确保计划的经济分析得到落实 我们将扩大 CHERISH 研究附属计划，使其能够在方法上合理且可行。 为从事药物滥用障碍的研究人员提供具有全国代表性的虚拟社区 治疗健康经济研究。利用现有研究并整合第三方数据。 数据集和管理记录，我们将开发用于评估个人的分析框架和工具 我们还将制定系统层面的物质使用障碍和相关实施干预措施。 与人口数据和建模合作进行适应性干预的经济评估方法。 核心，我们将协助研究人员利用外部数据来加强对经济评估的解读 结果。