Electronic cigarette use inside of vehicles and associated secondhand and thirdhand exposures

在车内使用电子烟以及相关的二手和三手暴露

基本信息

批准号：
10045614
负责人：
Eric Kendall Soule
金额：
$ 43.98万
依托单位：
EAST CAROLINA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-07 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10045614
关键词：
Acetaldehyde Acrolein Address Adult Aerosols Airborne Particulate Matter Behavior Behavioral Characteristics Chemicals Child Concentration measurement Dangerousness Data Deposition Detection Devices Electronic cigarette Epidemic Exposure to Flame Ionization Flavoring Formaldehyde Furans Gas Chromatography Generations Glycerol Health Human Indoor Air Quality Inhalation Intervention Irritants Laboratories Laws Liquid substance Location Malignant Neoplasms Measurement Measures Monitor Morbidity - disease rate Nature Nicotine Nitrosamines Participant Particle Size Particulate Matter Patient Self-Report Perception Persons Policies Prevalence Prevention Propylene Glycols Public Health Reporting Research Risk Sampling Services Smell Perception Social Marketing Surface Surgeon Survey Methodology Surveys Testing Time Tobacco Tobacco use Toxic effect United States United States Dept. of Health and Human Services Vegetables Visit Youth box mods cigarette smoke cigarette smoking e-cigarette aerosols electronic cigarette use electronic cigarette user indoor particulate matter insight liquid chromatography mass spectrometry mortality pod mods portability prevent tobacco prevention toxicant vape pens volatile organic compound

项目摘要

Project Summary Electronic cigarettes (ECIGs) are a diverse class of products that use an electric heater to aerosolize a liquid often containing propylene glycol, vegetable glycerin, nicotine, and chemical flavorants. While the aerosol generated from ECIG use contains lower concentrations of some chemicals found in cigarette smoke, research has demonstrated that ECIG aerosol contains harmful irritants and toxicants including propylene glycol, vegetable glycerin, nicotine, volatile organic chemicals, formaldehyde, acetaldehyde, acrolein, furans, chloropropanols, and tobacco specific nitrosamines. Despite the presence of these compounds in ECIG aerosol, many ECIG users perceive that ECIG use is associated with low harm. As a result, indoor ECIG use around non-ECIG users, including ECIG use inside of vehicles, is common. Research has demonstrated that indoor ECIG use can result in secondhand and thirdhand exposure to chemicals present in ECIG aerosol, but research has yet to examine ECIG use inside of vehicles and if use in this small space results in increased exposures to ECIG generated chemicals. The specific aims of this project are to 1) examine self-reported ECIG use behaviors and perceptions regarding ECIG use inside of vehicles, 2) measure concentrations of chemicals deposited on interior surfaces inside of ECIG users’ vehicles who report ECIG use in their vehicles, and 3) measure particulate matter concentrations inside of ECIG users’ vehicles during active ECIG use. This study will use online survey methods to examine ECIG use behaviors inside of vehicles (e.g., prevalence of ECIG use in vehicles, ECIG use with others in the vehicle, ECIG use with windows up/down, etc.) in a sample of adult current ECIG users. Additionally, ECIG users who report ECIG use inside their vehicles will present for an in person visit with their vehicles. Participants will include users of “pod mod” ECIG devices and “third generation” ECIG devices as well as controls (i.e., non-ECIG users with vehicles where no ECIG or tobacco use occurs). Samples will be collected from the interior surfaces of ECIG users’ vehicles (and control vehicles) and chemical analyses will detect and quantify the presence of chemicals found in ECIG aerosol. ECIG users will then engage in active ECIG use inside of their vehicles including a 10-puff directed bout (one puff every 30 seconds) and 20 minutes where they engage in ECIG use ad libitum. During ECIG use sessions, particulate matter concentrations will be measured inside of the vehicles. Expected results include that ECIG use inside of vehicles will be common among ECIG users and will be associated with high concentrations of chemicals and particulate matter inside of vehicles. These data will increase understanding of the prevalence and types of ECIG use behaviors that occur inside of vehicles as well as the secondhand and thirdhand exposures associated with ECIG use within vehicles by different types of ECIG devices. Successful completion of this project will help to identify the potential risks of ECIG use within vehicles and inform prevention efforts to avoid unwanted harmful exposures to ECIG generated chemicals.

项目概要电子烟 (ECIG) 是使用电加热器雾化液体的多种产品气雾剂通常含有丙二醇、植物甘油、尼古丁和化学香料。研究表明，使用 ECIG 产生的香烟烟雾中某些化学物质的浓度较低已证明 ECIG 气溶胶含有有害刺激物和有毒物质，包括丙二醇、植物甘油、尼古丁、挥发性有机化学物质、甲醛、乙醛、丙烯醛、呋喃、尽管 ECIG 中存在这些化合物，但氯丙醇和烟草特有的亚硝胺。气溶胶，许多 ECIG 用户认为使用 ECIG 危害较低，因此，室内 ECIG 使用。研究表明，在非 ECIG 用户周围，包括在车辆内使用 ECIG，这种情况很常见。室内 ECIG 使用可能会导致二手和三手接触 ECIG 气溶胶中存在的化学物质，但是研究尚未检验 ECIG 在车辆内部的使用，以及在这个狭小的空间中使用是否会导致增加该项目的具体目标是 1) 检查自我报告。 ECIG 使用行为和对车内 ECIG 使用的看法，2) 测量 ECIG 的浓度报告 ECIG 在其车辆中使用的 ECIG 用户车辆内表面沉积的化学物质， 3) 在 ECIG 主动使用期间测量 ECIG 用户车辆内的颗粒物浓度。研究将使用在线调查方法来检查 ECIG 在车内的使用行为（例如，样本中的 ECIG 在车辆中的使用、ECIG 与车辆中其他设备的使用、ECIG 在车窗升起/降下的情况下使用等）此外，报告车内使用 ECIG 的 ECIG 用户将出席。亲自参观他们的车辆的参与者将包括“pod mod”ECIG 设备和“第三者”的用户。一代”ECIG 设备以及控制装置（即，车辆上没有 ECIG 或烟草的非 ECIG 用户）样本将从 ECIG 用户车辆（和控制车辆）的内表面采集。化学分析将检测并量化 ECIG 气溶胶中化学物质的存在。然后将在车内积极使用 ECIG，包括 10 口定向抽吸（每 30 口抽一口）秒）和 20 分钟，他们随意使用 ECIG 在 ECIG 使用期间，颗粒物。预期结果包括 ECIG 在车内的使用。车辆在 ECIG 用户中将很常见，并且与高浓度的化学品和这些数据将增加对车辆内部颗粒物的流行程度和类型的了解。 ECIG 使用车内发生的行为以及二手和三手暴露与不同类型的 ECIG 设备在车辆内使用 ECIG 相关联成功完成此任务。该项目将有助于识别车辆内使用 ECIG 的潜在风险，并为预防工作提供信息，以避免意外有害地接触 ECIG 产生的化学物质。

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Secondhand electronic cigarette aerosol in vehicles impacts indoor air quality.

车内二手电子烟气溶胶会影响室内空气质量。

DOI：
发表时间：
2023-09-01
期刊：
影响因子：
4.2
作者：
Soule, Eric K;Sousan, Sinan;Pender, Jack;Thomas, Luke;Gold, Emily;Fresquez, Sarah;Mooring, Ronald;Coombs, Vivien;Gogineni, Anish;Tiet, Ale
通讯作者：
Tiet, Ale

Evidence of potential tobacco industry influence in Tobacco Regulatory Science.

烟草业对烟草监管科学的潜在影响的证据。

DOI：
发表时间：
2023-05
期刊：
影响因子：
5.2
作者：
Lee, Joseph G L;Soule, Eric K
通讯作者：
Soule, Eric K

Use of real-time monitors to evaluate the potential exposure of secondhand electronic cigarette particulate matter inside vehicles.

使用实时监测器评估车内二手电子烟颗粒物的潜在暴露情况。

DOI：
发表时间：
2023-11-01
期刊：
影响因子：
0
作者：
Sousan, Sinan;Mooring, Ronald;Fresquez, Sarah;Park, Yoo Min;Coombs, Vivien;Bertges, Nicole;Thomas, Luke;Gold, Emily;Gogineni, Anish;Tiet, Ale;Pender, Jack;Soule, Eric K
通讯作者：
Soule, Eric K

Laboratory Determination of Gravimetric Correction Factors for Real-time Area Measurements of Electronic Cigarette Aerosols.

电子烟气溶胶实时面积测量的重量校正因子的实验室测定。

DOI：
发表时间：
2022
期刊：
影响因子：
0
作者：
Sousan, Sinan;Pender, Jack;Streuber, Dillon;Haley, Meaghan;Shingleton, Will;Soule, Eric
通讯作者：
Soule, Eric

Electronic cigarette users' reactions and responses to a hypothetical ban of flavoured electronic cigarette liquids.

电子烟用户对调味电子烟液假设禁令的反应和反应。

DOI：
发表时间：
2022-11
期刊：
影响因子：
5.2
作者：
Soule, Eric K;Mayne, Shannon;Snipes, William;Thomas, Luke;Guy, Mignonne C;Breland, Alison;Fagan, Pebbles
通讯作者：
Fagan, Pebbles