Discovery of novel antileishmanial molecules from the plant Pentalinon andreuxii

从植物 Pentalinon andreuxii 中发现新型抗利什曼尼分子

• 批准号: 8083173
• 负责人: Abhay R Satoskar
• 金额: $ 80.4万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-21 至 2010-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8083173
• 关键词: Afghanistan; Amphotericin B; Animal Model; Animals; Antiparasitic Agents; Apoptotic; Army Personnel; Biological Factors; Biological Testing; Bite; Canis familiaris; Chemicals; Clinical Research; Country; Cutaneous; Data; Development; Disease; Drug resistance; Foundations; Fractionation; Future; Goals; Hexanes; Immunocompromised Host; Immunology; In Vitro; Individual; Infection; Iraq; Laboratories; Left; Leishmania; Leishmaniasis; Lesion; Mammalian Cell; Mediating; Methods; Mexico; Miltefosine; Mission; Mus; National Institute of Allergy and Infectious Disease; Parasites; Pathogenesis; Pathology; Pathway interactions; Patients; Permeability; Pharmaceutical Preparations; Pharmacology; Plant Components; Plant Roots; Plant Sources; Plants; Preclinical Testing; Quality Control; Rage; Resistance; Safety; Sand Flies; Secure; Soldier; Source; Sterols; Synthesis Chemistry; Testing; The science of Mycology; Toxic effect; Tropical Disease; Visceral Leishmaniasis; Work; analog; comparative efficacy; compliance behavior; conventional therapy; drug development; endophytic fungi; global health; in vivo; killings; macrophage; membrane polarity; neglect; novel; obligate intracellular parasite; prevent; resistant strain; response; safety testing; stem; vector