Core D: Special Populations

核心 D：特殊人群

• 批准号: 10006601
• 负责人: CURT G BECKWITH
• 金额: $ 33.61万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10006601
• 关键词: Accident and Emergency department; Address; Alcohol or Other Drugs use; Area; Centers of Research Excellence; Certificate of Confidentiality; Clinical Research; Clinical Trials Data Monitoring Committees; Clinics and Hospitals; Communities; Consultations; Course Content; Criminal Justice; Disadvantaged; Education and Outreach; Ethics; Evidence based treatment; Face; Faculty; Goals; Healthcare Systems; Hospitals; Imprisonment; Individual; Infrastructure; Institution; Institutional Review Boards; Interdisciplinary Study; Jail; Mediation; Medical; Mentors; Mission; Opioid; Overdose; Participant; Perinatal; Perinatal Care; Persons; Pharmaceutical Preparations; Population; Pregnant Women; Preparation; Prisoner; Prisons; Protocols documentation; Public Health; Research; Research Assistant; Research Design; Research Personnel; Resources; Rhode Island; Services; Special Population; Stigmatization; Structure; Study Subject; Substance Use Disorder; System; Training; Training Activity; Translational Research; Underserved Population; Universities; Vulnerable Populations; follow-up; human subject protection; illicit opioid; operation; opioid overdose; opioid treatment program; opioid use disorder; opioid user; overdose prevention; patient population; recruit; research study; webinar

PROJECT SUMMARY The goal of this proposal is to establish a multi-disciplinary research Center focused on the theme of opioids and overdose. This will necessarily include vulnerable and underserved populations. To support this general goal, the proposed Special Populations Core (SPC) will build infrastructure to recruit and retain vulnerable and underserved individuals, build capacity in the ethical conduct of research with vulnerable populations, and serve as a centralized resource for training and outreach regarding the conduct of research among individuals most impacted by overdose and opioid-related harms. The near-term, primary mission of the SPC is to support Project Leaders to recruit and retain opioid-involved individuals through multiple venues including emergency departments, opioid treatment programs (OTPs), hospital/perinatal offices and criminal justice (CJ) facilities; navigate the ethical considerations of engaging vulnerable populations, apply for Institutional Review Board approval and convene data safety monitoring boards. The long-term goal of the SPC is to build a sustainable resource to support the practical challenges posed when working with vulnerable and underserved populations across Rhode Island hospital networks and Brown and other local Universities and research institutions. The SPC will provide an array of services and expertise including: facilitating access to patient populations, providing research staff trained in best practices of recruitment and retention and negotiating various recruitment settings, guidance in human subjects protection and regulatory oversight of research conducted among vulnerable populations, and broaden the community of researchers addressing this critical public health issue through outreach and training in these topics, including the critical overlap of CJ involved populations, opioid use disorders and overdose. Dr. Curt Beckwith and Dr. Timothy Flanigan will be the faculty leaders of this Core. They will provide area expertise in working with CJ and substance using populations. Dr. Janette Baird, Scientific Advisor, will provide area expertise in research conducted among individuals with substance use disorders (SUD) in hospital Emergency Departments and Dr. Caron Zlotnick, Scientific Advisor, will provide area expertise in working with pregnant women with SUD. Michelle McKenzie, MPH, Core Manager, will oversee routine operations, manage Core resources, and provide area expertise in recruitment, tracking and follow-up of SUD populations. Ms. Martino, Training Coordinator, will focus on developing educational forum specific to the incarcerated setting. Two Research Assistants will provide recruitment and retention support for Project Leaders.

项目概要 该提案的目标是建立一个专注于阿片类药物主题的多学科研究中心 和过量。这必然包括弱势群体和服务不足的群体。为了支持这个将军 目标，拟议的特殊人群核心（SPC）将建设基础设施来招募和留住弱势群体 服务不足的个人，建设弱势群体研究道德行为的能力，以及 作为个人研究进行培训和推广的集中资源 受过量服用和阿片类药物相关危害影响最大。最高人民法院近期的主要任务是支持 项目负责人通过多个场所（包括紧急情况）招募和保留与阿片类药物有关的个人 部门、阿片类药物治疗计划 (OTP)、医院/围产期办公室和刑事司法 (CJ) 设施； 引导弱势群体参与的道德考虑，向机构审查委员会申请 批准并召集数据安全监察委员会。最高人民法院的长期目标是建立一个可持续发展的 支持弱势群体和服务不足人群工作时面临的实际挑战的资源 横跨罗德岛州医院网络以及布朗大学和其他当地大学和研究机构。这 SPC 将提供一系列服务和专业知识，包括：促进接触患者群体、 为研究人员提供招聘、保留和谈判各种最佳实践方面的培训 招募环境、人类受试者保护指导以及对所进行研究的监管监督 弱势群体，并扩大解决这一关键公共卫生问题的研究人员群体 通过这些主题的外展和培训来解决问题，包括 CJ 相关人群的关键重叠， 阿片类药物使用障碍和过量。 Curt Beckwith 博士和 Timothy Flanigan 博士将担任该核心的教师领导。他们会提供面积 与 CJ 和物质使用人群合作的专业知识。科学顾问 Janette Baird 博士将提供 在医院中对药物滥用障碍 (SUD) 患者进行研究的领域专业知识 急诊科和科学顾问 Caron Zlotnick 博士将提供与以下方面合作的领域专业知识： 患有 SUD 的孕妇。米歇尔·麦肯齐 (Michelle McKenzie)，公共卫生硕士，核心经理，将监督日常运营、管理 核心资源，并提供 SUD 人群招募、跟踪和随访方面的领域专业知识。多发性硬化症。 培训协调员马蒂诺将专注于开发针对监禁环境的教育论坛。 两名研究助理将为项目负责人提供招聘和保留支持。