2010 Oxygen Radicals: Mechanisms that Underpin Redox Biology - a Gordon Research

2010 氧自由基：支撑氧化还原生物学的机制 - 戈登研究

• 批准号: 7907172
• 负责人: Garry R Buettner
• 金额: $ 0.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-02-03 至 2011-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7907172
• 关键词: Address; Age; Aging; Area; Arts; Biochemical; Biochemistry; Biological Markers; Biology; Cardiovascular Diseases; Cells; Chemicals; Discipline; Disease; Enzymes; Equilibrium; Evaluation; Event; Free Radicals; Funding; Future; Health; Holidays; Human; Hydrogen Sulfide; Inflammation; Knowledge; Malignant Neoplasms; Methods; Mitochondria; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Oxides; Participant; Play; Pneumonia; Postdoctoral Fellow; Proteins; Reactive Oxygen Species; Research; Research Personnel; Role; Schedule; Scientist; Suggestion; Sulfhydryl Compounds; Superoxide Dismutase; Toxicology; Travel; United States; base; biological systems; biomedical scientist; clinically relevant; cost; design; frontier; graduate student; lectures; meetings; oxidation; posters; professor; programs; public health relevance; symposium

DESCRIPTION (provided by applicant): The Gordon Research Conference on "Oxygen Radicals: Mechanisms that Underpin Redox Biology" is designed to provide chemists, biologists, biochemists, cell biologists, clinicians, and other biomedical scientists with state-of-the-art knowledge on reactive oxygen species and their interactions with other radicals, including nitric oxide, in chemical and biological systems. This research conference is held every two years; the next meeting will be held February 7-12, 2010 at the Four Points Sheraton / Holiday Inn Express, Ventura, CA. Fifteen conferences have been held since 1981; they have proven to be extremely productive based on the large number of applicants and the post-meeting evaluations. Funds are requested to partially support travel, subsistence, and registration costs for speakers from the United States and abroad as well as productive graduate students/post-doctoral candidates. The speakers listed in this program were selected based on the suggestions from the previous chairs, co-chairs and attendees at the past conference. Speakers have been invited to present their latest research on the fundamentals of redox biology. Session topics will include: oxidative stress, redox biology, & disease; inflammation & oxidative stress; oxidative events in cardiovascular disease; biochemistry of thiol oxidation & thiol enzymes; nitrogen oxides & hydrogen sulfide; protein oxidation, redox changes & aging; mitochondria, central to redox balance; biomarkers & methods for detecting oxidative stress; and super oxide dismutases, past present and future. The invited speakers represent current and future leaders that address fundamental aspects of free radical and redox biology research that impacts inflammation, pulmonary and cardiovascular diseases, cancer, toxicology, and other issues of human health, including aging. In addition, Professor Joe McCord will present a Keynote Lecture entitled: "Superoxide Dismutase and Free Radical Biology: The Beginnings, the Present, and Trying to Guess the Future" Two separate poster sessions of two days each are scheduled for an anticipated 60-80 posters. Total attendance will be limited to 160 by Gordon Conference rules. The Gordon Research Conference provides an excellent and needed forum for the diversity of both participants and research areas. The main strength of this Gordon Research Conference is the opportunities offered for scientists in different disciplines to interact in an extended and uninterrupted fashion. This type of interaction generally results in new collaborative research initiatives. The Gordon Research Conference on Oxygen Radicals in Biology plays a crucial role in exploring frontier research in this important and clinically-relevant field. PUBLIC HEALTH RELEVANCE: The application seeks partial support for the 2010 Gordon Research Conference (GRC) on Oxygen Radicals: Mechanisms that underpin redox biology to be held in Ventura, CA Feb 7 -12 2010. This scientific meeting will provide a forum for the exchange of the most recent research findings in this field. Because of it emphasis on basic chemical and biochemical mechanisms in health and disease, it will be of benefit to a broad range of researchers, ranging from chemists to clinicians.

描述（由申请人提供）：戈登（Gordon）研究会议“氧激活：基础氧化还原生物学基础的机制”旨在为化学家，生物学家，生物化学家，细胞生物学家，临床医生和其他生物医学科学家提供对反应性氧气的最新知识，包括反应性氧气及其与其他自由基的相互作用，包括化学氧化物，包括化学氧化物（包括Nitricy氧化物）。 该研究会议每两年举行一次；下一次会议将于2010年2月7日至12日在加利福尼亚州文图拉的Sheraton / Holiday Inn Express的四点举行。自1981年以来举行了15次会议。根据大量申请人和会议后的评估，它们被证明具有极高的生产力。 要求资金部分支持美国和国外发言人的旅行，维持生计和注册费用，以及生产研究生/博士后候选人。 该计划中列出的演讲者是根据上任椅子，联合主席和与会者在上次会议上的建议选择的。 邀请演讲者介绍有关氧化还原生物学基础知识的最新研究。 会议主题将包括：氧化应激，氧化还原生物学和疾病；炎症和氧化应激；心血管疾病中的氧化事件；硫醇氧化和硫醇酶的生物化学；氮氧化物和硫化氢；蛋白质氧化，氧化还原变化和衰老；线粒体，氧化还原平衡的中心；用于检测氧化应激的生物标志物和方法；和超级氧化物张开，过去和未来。 受邀的演讲者代表了当前和未来的领导者，这些领导者解决了自由基和氧化还原生物学研究的基本方面，这些研究影响了炎症，肺和心血管疾病，癌症，毒理学以及其他人类健康问题，包括衰老。此外，乔·麦科德（Joe McCord）教授还将举行主题演讲，题为：“超氧化物歧化酶和自由基生物学：起点，现在和试图猜测未来”，“两天的两天的两个单独的海报都安排在预期的60-80海报上。 戈登会议规则的总出勤率将限制为160。 戈登研究会议为参与者和研究领域的多样性提供了一个出色的且需要的论坛。这次戈登研究会议的主要优势是为不同学科的科学家提供的机会，以扩展和不间断的方式进行互动。 这种类型的互动通常会导致新的合作研究计划。 戈登（Gordon）在生物学上的氧激活研究会议在探索这个重要且与临床相关的领域的边界研究中起着至关重要的作用。 公共卫生相关性：该申请寻求对2010年戈登研究会议（GRC）的部分支持：氧激活者：基础氧化还原生物学的机制将于2010年2月7日至12日在Ventura举行。这次科学会议将为该领域最新研究结果的交换提供一个论坛。由于它强调健康和疾病中的基本化学和生化机制，因此对从化学家到临床医生的广泛研究人员有益。