2010 FASEB Conference on the Retinoids

2010 年 FASEB 类视黄醇会议

• 批准号: 7911332
• 负责人: NOA NOY
• 金额: $ 4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7911332
• 关键词: Address; American; Arizona; Biological Process; Biology; Cells; Collaborations; Computer Retrieval of Information on Scientific Projects Database; Databases; Development; Diabetes Mellitus; Discipline; Disease; Embryonic Development; Functional disorder; Funding; Goals; Grant; Health; Homeostasis; Human; Immunity; Immunologist; International; Investigation; Learning; Malignant Neoplasms; Metabolism; Molecular; Nutritional; Obesity; Physiological; Physiology; Postdoctoral Fellow; Regulation; Request for Applications; Research; Research Activity; Research Personnel; Resort; Retinoid Receptor; Retinoids; Role; Scientist; Senior Scientist; Societies; Structural Biologist; Therapeutic; Time; Tretinoin; United States National Institutes of Health; Vision; Vitamin A; Work; career; cell growth regulation; cell type; disorder prevention; graduate student; insight; lectures; meetings; posters; prevent; research and development; skin disorder; stem cell biology; symposium

DESCRIPTION (provided by applicant): This application requests partial support for the 15th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Retinoids to be held at the Carefree Resort in Carefree, Arizona in June 13-18, 2010. This bi-annual research conference has been very well attended (ranging from 125 to 200 attendees over the past 25 years) and remains the sole major national and international conference that addresses the full spectrum of retinoid biology. Our understanding of the mechanisms of action and the biological functions of retinoids has increased rapidly over the last two decades. Nevertheless, there is much that still needs to be learned regarding retinoid actions in both normal human physiology and pathophysiology. To meet this need for information, there is a great deal of ongoing research activity focused on the retinoids (the NIH CRISP database indicates that there are currently 284 funded NIH grants involving retinoid biology). The 2010 conference will consist of a plenary lecture, platform presentations and poster sessions that will allow for the exchange of new research findings amongst scientific attendees. The main topics to be addressed at the conference include: (1) retinoid metabolism and homeostasis; (2) retinoid receptors; (3) enzymatic control of retinoic acid action; (4) retinoids in vision; (5) retinoids in cancer; (6) physiological actions of retinoids; (7) retinoids in development; (8) retinoid regulation of cell growth and differentiation; and (9) retinoid regulation of stem cell biology. The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their newest research findings that share a common focus on the retinoids. This conference will provide a forum for the critical review of recent research and for the development of new research ideas and collaborations. This will stimulate new investigations that in time will provide needed insight into the essential actions of retinoids in preventing disease and maintaining health. Narrative Retinoids, the active forms of vitamin A, have wide ranging effects on many aspects of human health including vision, embryonic development, immunity, and differentiation of diverse cell types. Retinoids are important therapeutics for skin disorders and cancer, and they are involved in diabetes/obesity and certain ocular diseases. This bi-annual research conference provides the sole major national and international forum that addresses the full spectrum of retinoid biology. Its goal is to stimulate scientific exchange and new investigations that will provide needed insights into the roles of retinoids in disease prevention and treatment.

描述（由申请人提供）：本申请要求对美国实验生物学联合会（FaseB）第15联合联合会（FASEB）夏季研究会议在2010年6月13日至18日在亚利桑那州的无忧无虑度假胜地举行，这是在125年至200年的时间里（过去的25年），及以前的25年及其整个会议的整个会议）维生素生物学。在过去的二十年中，我们对视力素的作用机理和维生素的生物学功能的理解迅速增加。然而，在正常的人类生理学和病理生理学中，仍然需要学习很多关于类维生素类动作的知识。为了满足对信息的需求，有很多持续的研究活动集中在类维生素类似的情况下（NIH CRISP数据库表明目前有284家资助的NIH赠款涉及视网膜类似生物学）。 2010年的会议将包括全体演讲，平台演示和海报会议，该会议将允许在科学与会者中交换新的研究结果。会议上要解决的主要主题包括：（1）类维生素性代谢和稳态； （2）类视黄素受体； （3）视黄酸作用的酶控控制； （4）视力符合视力； （5）癌症中的类视黄素； （6）类维生素类似的生理作用； （7）开发的类视黄素； （8）细胞生长和分化的类维生素性调节； （9）干细胞生物学的类视黄素调节。 The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, biophysicists, structural biologists,免疫学家，化学家和临床医生）介绍和讨论其最新的研究结果，这些研究结果共同关注类维生素类动物。这次会议将为对最新研究的批判性审查以及新的研究思想和合作的发展提供论坛。这将刺激新的调查，即及时将提供所需的洞察力，了解性类维生素类动物在预防疾病和维持健康方面的基本作用。 叙述 维生素A的活性形式的类视网膜类似对人类健康的许多方面都有广泛的影响，包括视觉，胚胎发育，免疫力和不同细胞类型的分化。类维生素类动物是皮肤疾病和癌症的重要疗法，它们参与糖尿病/肥胖症和某些眼部疾病。这次两年一次的研究会议提供了唯一的主要国家和国际论坛，该论坛涉及类视网膜生物学的全部范围。它的目标是刺激科学交流和新的研究，这些研究将为类视视视网想中疾病预防和治疗的作用提供必要的见解。