SCH: Interface Monitoring System to Promote Residual Limb Health

SCH：促进残肢健康的接口监控系统

• 批准号: 9313641
• 负责人: Todd P Coleman
• 金额: $ 34.79万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-22 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9313641
• 关键词: Address; Amputation; Biological Models; Blood Vessels; Blood flow; California; Caring; Cephalic; Chicago; Computational algorithm; Computer Simulation; Custom; Data; Development; Devices; Early Diagnosis; Education; Electromyography; Electronics; Engineering; Environment; Exhibits; General Population; Generations; Goals; Health; Health Status; Healthcare; Helmet; Hospitals; Hydration status; Illinois; Imaging Device; Impairment; Industry; Information Sciences; Learning; Limb Prosthesis; Lower Extremity; Medical; Medical Device; Medicine; Mission; Molds; Monitor; National Institute of Biomedical Imaging and Bioengineering; Orthotic Devices; Patient Care; Patients; Pattern Recognition; Persons; Prevention; Preventive; Property; Prosthesis; Research; STEM field; Sensory; Skin; Societies; Spinal; Statistical Algorithm; Stretching; System; Techniques; Technology; Temperature; Tissues; Underrepresented Students; Universities; Wireless Technology; Work; arm; base; bioimaging; clinical practice; computer science; computerized data processing; design; evidence base; flexibility; high risk population; improved; instrumentation; lectures; operation; person centered; pressure; prevent; residual limb; residual limb health; science museum; sensor; signal processing; skin organogenesis; summer research; symposium; tool; transmission process; undergraduate student; user-friendly

This proposal aims to develop a stretchable and flexible sensor technology capable of transforming healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, and person-centered. The goal is to offer 'skin-like' properties, to enable intimate, complete non-invasive integration with the patient. The resulting 'epidermal' electronic devices may allow clinicians to monitor their patients, and the general public to assess, continuously, their health and well-being. The proposed interface monitoring system, designed to promote residual limb health in persons who wear prostheses, in physical forms that are 'skin like', may demonstrate key technological and scientific advancements towards evidenced-based and person-centered prosthetic care. The work involves " Development of 'skin-like' pressure, strain and temperature sensors, with wireless operation, as well as hydration and blood flow sensors. " Development of computational modeling and algorithms for statistical signal processing of the sensor data and pattern recognition to create a user-friendly interface for clinicians and patients. " Application of the proposed sensor technologies and data processing and pattern recognition techniques to prosthetic clinical practice. The continuous capture, storage and transmission of sensor data are critical to the design of lower limb prosthetics for improved health and healthcare. The proposed work is consonant with the mission of NIBIB to improve health by leading development of new biomedical imaging devices for early detection and prevention of health problems and assessment of health status. In addition to prosthetic care, the proposal may address an unmet need for a model system for individualized healthcare, in which continuous sensing, monitoring and assessment are performed using wireless epidermal sensors instead of traditional lab-based instrumentation.

该提案旨在开发一种可拉伸且灵活的传感器技术，能够改变 医疗保健从被动的、以医院为中心的到预防性的、主动的、基于证据的和 以人为本。目标是提供“皮肤般”的特性，以实现亲密、完全非侵入性的 与患者融为一体。由此产生的“表皮”电子设备可以让临床医生监测他们的情况 患者和公众持续评估他们的健康和福祉。建议的接口 监测系统，旨在促进佩戴假肢者的残肢健康，在身体方面 “类似皮肤”的形式可能会展示关键的技术和科学进步 循证且以人为本的假肢护理。工作涉及 “开发具有无线操作功能的‘类皮肤’压力、应变和温度传感器，以及 水合和血流传感器。 “开发传感器数据统计信号处理的计算模型和算法 和模式识别，为临床医生和患者创建用户友好的界面。 “所提出的传感器技术以及数据处理和模式识别技术的应用 到假肢临床实践。传感器数据的连续捕获、存储和传输对于 用于改善健康和医疗保健的下肢假肢设计。 拟议的工作与 NIBIB 的使命相一致，即通过领导新的开发来改善健康 用于早期发现和预防健康问题以及健康评估的生物医学成像设备 地位。除了假肢护理之外，该提案还可以解决对模型系统的未满足需求 个性化医疗保健，其中使用进行连续感测、监测和评估 无线表皮传感器代替传统的实验室仪器。

项目成果

Chemical Sensing Systems that Utilize Soft Electronics on Thin Elastomeric Substrates with Open Cellular Designs.

在具有开放式蜂窝设计的薄弹性基板上利用软电子的化学传感系统。

• 发表时间: 2017-03-03
• 影响因子: 19
• 作者: Lee, Yoon Kyeung;Jang Prof, Kyung;Ma, Yinji;Koh Prof, Ahyeon;Chen, Hang;Jung, Han Na;Kim, Yerim;Kwak, Jean Won;Wang Dr, Liang;Xue, Yeguang;Yang, Yiyuan;Tian, Wenlong;Jiang, Yu;Zhang Prof, Yihui;Feng Prof, Xue;Huang Prof, Yonggang;Rogers
• 通讯作者: Rogers

Mechanical Designs for Inorganic Stretchable Circuits in Soft Electronics.

软电子学中无机可拉伸电路的机械设计。

• 发表时间: 2015-09
• 作者: Wang, Shuodao;Huang, Yonggang;Rogers, John A
• 通讯作者: Rogers, John A

Super-Absorbent Polymer Valves and Colorimetric Chemistries for Time-Sequenced Discrete Sampling and Chloride Analysis of Sweat via Skin-Mounted Soft Microfluidics.

通过皮肤安装软微流体对汗液进行时间序列离散采样和氯化物分析的超吸水性聚合物阀门和比色化学。

• DOI: 10.1002/smll.201703334
• 发表时间: 2018-03-01
• 期刊: Small
• 影响因子: 13.3
• 作者: Sung Bong Kim;Yi Zhang;S. Won;A. B;odkar;odkar;Yurina Sekine;Yeguang Xue;Jahyun Koo;S. Harshman;Jennifer A. Martin;Jeong Min Park;Tyler R. Ray;Kaitlyn E. Crawford;Kyu‐Tae Lee;Jungil Choi;Rhonda L Pitsch;Claude C. Grigsby;A. Strang;Yu;Shuai Xu;Jeonghyun Kim;Ahyeon Koh;J. Ha;Yonggang Huang;Seung Wook Kim;J. Rogers
• 通讯作者: J. Rogers

Three-Dimensional Silicon Electronic Systems Fabricated by Compressive Buckling Process.

通过压缩屈曲工艺制造的三维硅电子系统。

• DOI: 10.1021/acsnano.8b00180
• 发表时间: 2018-04-11
• 期刊: ACS nano
• 影响因子: 17.1
• 作者: Bong Hoon Kim;Jungyup Lee;S. Won;Zhaoqian Xie;Jan;Yongjoon Yu;Y. Cho;Hokyung Jang
• 通讯作者: Hokyung Jang

Soft, skin-mounted microfluidic systems for measuring secretory fluidic pressures generated at the surface of the skin by eccrine sweat glands.

柔软的、安装在皮肤上的微流体系统，用于测量小汗腺在皮肤表面产生的分泌流体压力。

• DOI: 10.1039/c7lc00525c
• 发表时间: 2017-07-25
• 期刊: Lab on a chip
• 影响因子: 6.1
• 作者: Choi J;Xue Y;Xia W;Ray TR;Reeder JT;Bandodkar AJ;Kang D;Xu S;Huang Y;Rogers JA
• 通讯作者: Rogers JA