Jungers Center New Faculty Recruitment in Genetic Models of Axonal Degeneration

荣格斯中心轴突变性遗传模型新教师招聘

基本信息

批准号：
7943930
负责人：
Dennis Neil Bourdette
金额：
$ 65.36万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2012-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7943930
关键词：
Alzheimer&apos s Disease Amyotrophic Lateral Sclerosis Animal Model Appointment Area Arts Award Axon Axonal Transport Basic Science Biological Models Biology Biomedical Research Caenorhabditis elegans California Camping Cellular biology Clinical Clinical Research Coffee Collaborations Commit Communities Development Disease Drosophila genus Environment Equipment Faculty FarGo Fellowship Floor Freezing Funding Genetic Models Genetic Techniques Gifts Hand Health Sciences Housing Human Resources Image Infusion procedures Institutes Invertebrates Investigation Laboratories Laboratory Research Lead Life Light Lipid Biochemistry Massachusetts Mediation Microscopic Microscopy Mission Molecular Molecular Genetics Multiple Sclerosis Myelin Natural regeneration Neurobiology Neurology Neurosciences Neurosciences Research Oligodendroglia Oregon Pathogenesis Pathway interactions Positioning Attribute Postdoctoral Fellow Principal Investigator Procedures Proteins Recruitment Activity Research Research Infrastructure Research Personnel Resources Role Schwann Cells Scientist Side Students System Time Training United States National Institutes of Health Universities University Hospitals Visit Wages Walking Washington Work axonal degeneration cellular imaging college cost design experience falls graduate student in vivo interest lectures light microscopy member programs ranpirnase research facility square foot symposium translational neuroscience web site

项目摘要

DESCRIPTION (provided by applicant): The Jungers Center for Neurosciences Research proposes to recruit a newly-independent neuroscientist to expand and enhance its research efforts around the theme of Axonal Degeneration and Regeneration. Founded in 2006, the Jungers Center is a new and evolving disease-oriented research center being jointly developed by the Department of Neurology and Vollum Institute at Oregon Health & Science University (OHSU). The overall mission of the Jungers Center is to promote disease-oriented basic neuroscience research and thereby serve as a bridge between the robust clinical research programs in the Department of Neurology and the outstanding molecular and cellular basic neuroscience research laboratories in the Vollum Institute. The Center has 7,500 square feet of contiguous, open-design laboratory space in the new Biomedical Research Building on the main OHSU campus. We have used a generous gift from a local philanthropist to recruit faculty for the Center and equip an outstanding light microscopic imaging facility. The Center's initial three faculty members have basic science expertise in cell biology and live-cell imaging, protein and lipid biochemistry, and oligodendrocyte/myelin biology - each with a particular focus related to axonal degeneration and regeneration in mammalian systems. With funds provided by the PSO award, we would recruit a newly-independent neuroscientist for a full-time research position with a tenure-track equivalent appointment and substantial long term salary support... This new faculty member would bring complementary expertise to the Jungers Centers in the area of Invertebrate Genetic Model Systems of Axonal Degeneration and Regeneration. While we have new laboratory space and resources for long term salary support for the proposed new faculty member, we lack the resources for initial start-up costs. Recruiting an outstanding basic neuroscientist that uses advanced genetic techniques to investigate axonal degeneration and regeneration in an invertebrate model system, such as Drosophila or C. elegans. Would synergize with the current faculty and create a critical mass of scientists focused on understanding the genetic and molecular pathways of axonal degeneration and regeneration.

描述（由申请人提供）：Jungers神经科学研究中心提议招募新独立的神经科学家，以扩大和增强其围绕轴突退化和再生主题的研究工作。 Jungers Center成立于2006年，是一个由俄勒冈州健康与科学大学（OHSU）的神经病学和Vollum研究所共同开发的新的，面向疾病的研究中心。 Jungers中心的整体任务是促进面向疾病的基本神经科学研究，从而成为神经病学系的强大临床研究计划与Vollum Institute的杰出分子和细胞基本神经科学研究实验室之间的桥梁。该中心在主要OHSU校园的新生物医学研究大楼中拥有7,500平方英尺的连续开放设计实验室空间。我们已经使用了当地慈善家的慷慨礼物来招募该中心的教职员工，并配备了出色的轻型成像设施。该中心的最初三名教职员工在细胞生物学和活细胞成像，蛋白质和脂质生物化学以及少突胶质细胞/髓磷脂生物学方面具有基础科学专业知识，每个都具有与哺乳动物系统中轴突变性和再生有关的特定重点。借助PSO奖提供的资金，我们将招募新的独立的神经科学家担任全日制研究职位，并具有同等的终身任命和大量的长期薪水支持...这位新的教职员工将为无危险遗传模型系统的Jungers Centers带来互补的专业知识。尽管我们拥有新的实验室空间和资源，以为拟议的新教师提供长期薪水支持，但我们缺乏初始启动成本的资源。招募了一种出色的基本神经科学家，该神经科学家使用先进的遗传技术来研究无脊椎动物模型系统（例如果蝇或秀丽隐杆线虫）中的轴突变性和再生。将与当前的教职员工协同作用，并创建大量的科学家，专注于理解轴突变性和再生的遗传和分子途径。