Estrogen and cognition over the lifespan

雌激素与整个生命周期的认知

• 批准号: 8135098
• 负责人: THOMAS C FOSTER
• 金额: $ 27.1万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-15 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8135098
• 关键词: Age; Age-associated memory impairment; Aging; Alzheimer' s Disease; American; Animals; Behavioral; Biological Assay; Cognition; Dendritic Spines; Development; Disease; Down-Regulation; Effectiveness; Elderly; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptors; Estrogens; Etiology; Exhibits; Female; Future; Gene Delivery; Gene Expression; Gene Targeting; Genetic Polymorphism; Goals; Health; Hippocampus (Brain); Hormone Receptor; Hormones; Human; Impaired cognition; Impairment; Incidence; Intervention; Knock-out; Knockout Mice; Longevity; Mediating; Memory; Memory Loss; Memory impairment; Menopause; Molecular; Motion; Mus; Neurodegenerative Disorders; Personal Satisfaction; Prevalence; Proteins; Public Health; Rattus; Receptor Gene; Research; Role; Signal Transduction; Small Interfering RNA; Staging; Synapses; Testing; Therapeutic; Therapeutic Effect; Tissues; Viral; Viral Vector; Wild Type Mouse; Woman; Work; age related; aged; design; gene therapy; improved; in vivo; inhibitor/antagonist; juvenile animal; middle age; molecular marker; normal aging; novel strategies; prevent; programs; public health relevance; receptor; receptor expression; research study; response; synaptogenesis; therapy design; therapy development; vector