DEVELOPING SUSTAINABLE HIV CLINICAL TRIALS RESEARCH CAPACITY IN UGANDA

发展乌干达可持续的艾滋病毒临床试验研究能力

• 批准号: 7680449
• 负责人: Philippa Musoke
• 金额: $ 2.48万
• 依托单位: MU-JHU CARE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-08 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7680449
• 关键词: AIDS prevention; Address; Adult; Africa; Ally; Anti-Retroviral Agents; Applications Grants; Asia; Caring; Child; Childhood; Clinical Trials; Collaborations; Communicable Diseases; Country; Development; Educational Curriculum; Europe; European; Faculty; Funding; Grant; HIV; Human Resources; Institutes; Institution; International; Laboratory Research; Monitor; Monitoring Clinical Trials; Mothers; Prevention; Preventive Intervention; Protocols documentation; Research; Research Personnel; Research Training; Resources; Training; Training Activity; Training Programs; Uganda; United States National Institutes of Health; Universities; medical schools; multidisciplinary; programs; public health relevance; transmission process; virtual

DESCRIPTION (provided by applicant): Uganda is one of the resource limited countries where several successful clinical trials on the Prevention of Mother- To- Child HIV Transmission (PMTCT) have been conducted. Several other HIV prevention interventions, as well as advances in adult and pediatric antiretroviral treatment have also been implemented from clinical trials. Whereas the number of clinical trials has been on the rise over the last 10 years, there needs to be a proportional increase in the capacity development of well trained human resource available in the country to conduct and monitor clinical trials. There is a need to increase the numbers of scientific researchers, clinical trial managers and support staff who are well trained to independently conduct HIV clinical trials, and related laboratory research. We propose to create a sustainable training program in the conduct and monitoring of HIV clinical trials in the country. We will involve Makerere University Medical School and the affiliated research Institutions as well as the "young" Universities in the country such as Mbarara (west) and Gulu (north). The 2 year planning grant application from MU-JHU CARE in partnership with the Infectious Diseases Institute (IDI), Makerere aims to develop a research training program addressing management of clinical trials research on PMTCT and pediatric/adult HIV treatment. We plan to develop a multidisciplinary clinical trials research training curriculum focused on Ugandan researchers and allied protocol team staff. We will also identify and develop a world class global "virtual" faculty of HIV clinical trials research experts from Uganda, Africa, Asia, Europe and U.S. In addition, the Training Advisory Group will provide guidance for the planned program and trainees including the full training grant application in 2010. During the planning and in the long term, we will continue ongoing collaborations with foreign AITRP collaborating institutions including Johns Hopkins U. other U.S. and European Universities, and other funding groups such as the MRC which will provide HIV research training opportunities to both Ugandan investigators, allied research staff and foreign collaborating institution partners. PUBLIC HEALTH RELEVANCE: The proposed planning and training activities to develop HIV related Clinical Trials Research Capacity in Uganda are extremely relevant to NIH supported HIV related research in resource limited settings such as Uganda. The Planning grant will help address NIH efforts commitment to capacity strengthening and training of international researchers to carry out HIV research.

描述（由申请人提供）：乌干达是有限资源的国家之一，在该国家进行了几项有关预防母亲艾滋病毒传播（PMTCT）的成功临床试验。还通过临床试验实施了其他几种HIV预防干预措施，以及成人和小儿抗逆转录病毒治疗的进展。尽管在过去的10年中，临床试验的数量一直在增加，但该国可用训练有素的人力资源的能力发展需要增加，以进行和监测临床试验。有必要增加经过良好培训可以独立进行HIV临床试验以及相关实验室研究的科学研究人员，临床试验经理和支持人员的数量。我们建议在该国对艾滋病毒临床试验的行为和监测中制定可持续的培训计划。我们将参与Makerere大学医学院和附属研究机构以及该国的“年轻”大学，例如Mbarara（West）和Gulu（North）。 Mu-jhu Care的2年计划赠款申请与传染病研究所（IDI）合作，Makerere旨在制定一项研究培训计划，以解决有关PMTCT和PMTCT和儿科/成人HIV治疗的临床试验研究的管理。我们计划开发针对乌干达研究人员和盟军协议团队工作人员的多学科临床试验研究培训课程。我们还将确定并开发来自乌干达，非洲，亚洲，欧洲和美国的HIV艾滋病毒临床试验研究专家的世界一流的全球“虚拟”学院，此外，培训咨询小组还将为计划的计划和受训者提供指导，包括2010年的全面培训授予申请。作为将为乌干达调查人员，盟军研究人员和外国合作机构合作伙伴提供HIV研究培训机会的MRC。公共卫生相关性：在乌干达开发与HIV相关的临床试验研究能力的拟议规划和培训活动与NIH支持的HIV相关研究非常相关。计划赠款将有助于解决NIH的努力，致力于对国际研究人员进行艾滋病毒研究的能力加强和培训。