Molecular Characterization of Stage I Lung Cancer

I 期肺癌的分子特征

• 批准号: 8131392
• 负责人: MING YOU
• 金额: $ 16.82万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-17 至 2011-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8131392
• 关键词: Adjuvant; Adjuvant Chemotherapy; Adjuvant Therapy; Adverse effects; Apoptosis; BCL2 gene; BIK gene; CASP10 gene; CASP8 gene; Cancer Etiology; Cancer Patient; Cancer and Leukemia Group B; Cessation of life; Clinical; Curative Surgery; Custom; Data; Data Set; Diagnostic; Excision; Freezing; Future; Gene Expression Profile; Genes; Goals; Histopathology; Human; IL8RB gene; INHA gene; International; Malignant neoplasm of lung; Messenger RNA; Meta-Analysis; Microarray Analysis; Molecular; NID gene; Neoplasm Metastasis; Non-Small-Cell Lung Carcinoma; Operative Surgical Procedures; Outcome; Paraffin Embedding; Pathologist; Patients; Proteins; RNA; Recurrence; Recurrent disease; Relapse; Resected; Resources; Risk; Sampling; Series; Son; Staging; Subgroup; Testing; Tissue Microarray; Tissues; Tumor Tissue; United States; Validation; aggressive therapy; collaborative trial; design; effective therapy; high risk; improved; molecular marker; patient population; presenilin-1; tumor; validation studies

项目成果

MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer.

I 期肺癌的 MicroRNA 分析和复发/无复发生存预测。

• DOI: 10.1093/carcin/bgs100
• 发表时间: 2012-05-01
• 期刊: Carcinogenesis
• 影响因子: 4.7
• 作者: Yan Lu;R. Govindan;Liang Wang;Peng;B. Goodgame;Weidong Wen;Ananth Sezhiyan;J. Pfeifer
• 通讯作者: J. Pfeifer

Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients.

基因表达特征可预测 I 期非小细胞肺癌患者术后复发。

• 发表时间: 2012
• 影响因子: 3.7
• 作者: Lu, Yan;Wang, Liang;Liu, Pengyuan;Yang, Ping;You, Ming
• 通讯作者: You, Ming

Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients.

外显子组测序将 MXRA5 鉴定为一种在中国非小细胞肺癌患者中频繁突变的新型癌症基因。

• DOI: 10.1093/carcin/bgs210
• 发表时间: 2012-09-01
• 期刊: Carcinogenesis
• 影响因子: 4.7
• 作者: Donghai Xiong;Guangming Li;Kezhen Li;Qinzi Xu;Zhongjie Pan;F. Ding;P. Vedell;Pengyuan Liu;P.
• 通讯作者: P.