Imaging Core

成像核心

• 批准号: 7944551
• 负责人: RONALD LYNCH
• 金额: $ 18.87万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-19 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944551
• 关键词: 3-Dimensional; Address; Advisory Committees; Algorithms; Antineoplastic Agents; Area; Arizona; Arts; Biological Markers; Bioluminescence; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Trials; Commit; Communities; Computer software; Confocal Microscopy; Consultations; Core Facility; Custom; Data Analyses; Detection; Development; Economics; Endoscopy; Equipment; Fiber Optics; Gene Expression; Goals; Housing; Image; Image Analysis; Imaging Device; Imaging technology; Internet; Ions; Magnetic Resonance Imaging; Maintenance; Malignant Neoplasms; Microscope; Mission; Modality; Mus; Operative Surgical Procedures; Optics; Patients; Pharmaceutical Preparations; Protocols documentation; Research; Research Personnel; Series; Services; Spectrum Analysis; Suggestion; Technical Expertise; Techniques; Technology; Training; cost; image processing; improved; in vivo; instrument; luminescence; member; molecular imaging; oncology; optical imaging; pre-clinical; programs; response; single photon emission computed tomography; software development; statistics; web site

9.1.7 IMAGING CORE SHARED SERVICE The Cancer Center and affiliated programs house equipment and expertise in the development and application of a variety of in vivo imaging modilities including PET/SPECT, MR and optical approaches to in vivo imaging. The mission of the Imaging Core service is to provide Cancer Center members easy access to these state-of-the art in vivo imaging capabilities. Within this context, the Imaging Core provides three specific services to the Cancer Center members. An Institutional Imaging Advisory Committee provides a mechanism through which investigators may initiate projects, have them critically reviewed and facilitate access to appropriate image acquisition modalities. Optical imaging capabilities in confocal imaging, bioluminescence analysis of gene expression, and confocal endoscopy and spectroscopy are provided. The Core also provides access to technical expertise for operating and analyzing data acquired for pre-clinical MRI, PET/SPECT, and OCT, as well as. Clinical MRI approaches. A second area of focus, the Core is responsible for developing standardized platforms for image analysis housed in a centralized facility where experts in image processing and development of custom analysis algorithms are consolidated. The image processing facility, housed in the MRB, provides access to high end graphics computing capabilities, and experts who can provide both basic training and advice in image analysis approaches, as well as expertise to develop and customize specific image processing techniques. Thirdly, the Imaging Response Assessment Team (IRAT) has been incorporated into the ICSS for this renewal. The goal of this program is to increase the use of functional and molecular imaging endpoints as biomarkers in clinical drug trials. As such, all protocols initiated by AZCC investigators are vetted by the IRAT committee, who provide documented suggestions for inclusion of imaging endpoints. Consequently, the IRAT at AZCC will strictly conform to the ideals and concepts of the IRAT program and is committed to participating in the national consortium of IRATs focused on the use of quantitative imaging in clinical trials.

9.1.7成像核心共享服务 癌症中心和附属计划的房屋设备以及在开发和应用方面的专业知识 各种体内成像模式，包括PET/SPECT，MR和体内成像的光学方法。这 成像核心服务的任务是为癌症中心成员轻松访问这些最新技术 体内成像功能。在这种情况下，成像核为癌症提供了三个特定服务 中心成员。机构成像咨询委员会提供了一种机制 调查人员可以启动项目，对他们进行严格审查并促进访问适当的图像 采集方式。共聚焦成像中的光学成像能力，基因生物发光分析 提供了表达，共聚焦内窥镜和光谱法。核心还提供技术访问 用于运营和分析用于临床前MRI，PET/SPECT和OCT的数据的专业知识以及。 临床MRI接近。第二个重点领域，核心负责开发标准化平台 用于图像分析，位于集中式设施中 分析算法是合并的。位于MRB中的图像处理设施可提供高高的访问权限 结束图形计算功能，以及可以在图像中提供基础培训和建议的专家 分析方法以及开发和自定义特定图像处理技术的专业知识。 第三，成像响应评估团队（IRAT）已纳入了ICS的续订。 该程序的目的是增加功能和分子成像终点作为生物标志物的使用 临床药物试验。因此，AZCC调查人员发起的所有协议均由IRAT委员会审查，后者 提供有关包含成像端点的文献建议。因此，AZCC的IRAT将严格严格 符合IRAT计划的理想和概念，并致力于参加国家 IRAT的联盟重点是在临床试验中使用定量成像。