Bioethics Research Infrastructure Initiative: National Center on Minority Health

生物伦理学研究基础设施倡议：国家少数民族健康中心

• 批准号: 7941056
• 负责人: Luther S Williams
• 金额: $ 55.99万
• 依托单位: TUSKEGEE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-27 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7941056
• 关键词: Address; African American; Age; Aging; Alzheimer' s Disease; Awareness; Bioethical Issues; Bioethics; Biomedical Research; Cardiovascular Diseases; Caring; Clinical; Clinical Research; Clinical Trials; Collaborations; Communities; Community Health Education; Community Healthcare; Community Outreach; Complex; Continuing Education; Development; Diabetes Mellitus; Discipline of Nursing; Disease; Distance Education; Education; Educational Curriculum; Elderly; Enrollment; Ethnic Origin; Faculty; Fellowship; Genetic; Goals; Health; Health Occupations; Health Personnel; Health Professional; Health Services Research; Healthcare; Hypertension; Individual; Institution; Intervention; Knowledge; Language; Lead; Malignant Neoplasms; Medical Technology; Medicine; Minority; Minority Groups; Modeling; Perception; Pharmacy facility; Population; Population Heterogeneity; Principal Investigator; Race; Recording of previous events; Research; Research Design; Research Infrastructure; Research Personnel; Research Technics; Research Training; Role; Site; Students; Sum; Training; Training Programs; Underrepresented Minority; United States National Institutes of Health; Universities; Ursidae Family; Washington; abstracting; aged; community based participatory research; community organizations; cultural competence; design; evidence base; experience; health disparity; health economics; knowledge base; maltreatment; meetings; minority health; multidisciplinary; outreach; programs; research study

Abstract The Tuskegee University (TU) National Center for Bioethics in Research and Health Care, in conjunction with our collaborators at Washington University, seeks support for a project focused on the development of comprehensive and effective approaches, strategies and programs to effectively increase minority recruitment and retention into clinical trials. Longstanding mistrust is a principal barrier to minority research participation and is substantially owing to the nation's longstanding history of mistreatment of diverse populations for biomedical research. Widening health disparities, increasing use of medical technologies and genetic information, and the cultural competency of researchers in an era of increased cultural and language diversity heighten the impact of these barriers. The Washington University (WU) Alzheimer's Disease Research Center's African American Outreach Satellite conducts minority outreach and recruitment programs and defines and addresses barriers to Alzheimer's disease research participation. This highly successful interdisciplinary model will be modified and replicated at both TU and WU with (i) a focus on enrolling minority elderly in clinical trials (in general), (ii) advancing the empirical knowledge of recruitment of minority elderly for clinical trials, (iii) elaborating underlying bioethical factors, and (iv) training researchers and healthcare professionals who serve aged populations. Specifically, TU will conduct a nationally significant bioethics training program for health professionals and concomitantly address bioethics in clinical research, inclusive of research designs, statistical analyses, health economics, health disparities, and health information access and dissemination. By building on the expertise and differential roles of each academic site, we proposed to effect the transition from limited and often anecdotal representations to a multifaceted, multidisciplinary, and robust partnership to yield an aggregate research design of greater consequentiality, owing the strands being built to create a research and training agenda much stronger than the sum of the individual parts. We hypothesize that a community-based, evidence-informed, multidisciplinary systematic recruitment and retention program will lead to increased recruitment and retention of underserved minorities to yield participation rates sufficient to achieve the objectives of clinical trials. Principal Investigator/Project Director: Williams, Luther S.

摘要Tuskegee University（TU）与华盛顿大学的合作者一起，在研究和医疗保健领域的国家生物伦理学中心摘要，寻求致力于开发全面有效的方法，策略和计划的项目，以有效地增加少数民族的招聘和保留，并将其保留到临床试验中。长期的不信任是少数群体研究参与的主要障碍，并且基本上是由于该国长期以来虐待生物医学研究人群的历史。在文化和语言多样性增加的时代，扩大健康差异，增加医疗技术和遗传信息的使用以及研究人员的文化能力增加了这些障碍的影响。华盛顿大学（WU）阿尔茨海默氏病研究中心的非裔美国人外展卫星进行少数群体外展和招聘计划，并定义并解决了阿尔茨海默氏病研究参与的障碍。这种非常成功的跨学科模型将在TU和WU上进行修改和复制，（i）重点是让少数群体参加临床试验（一般），（一般而言），（ii）促进少数族裔老年人招募临床试验的经验知识，（iii）阐述生物etheactial toculation in Bioethical Seartial Consure and（IIV）培训培训的研究员和培训专业人士和卫生研究员。具体而言，TU将针对卫生专业人员进行全国重要的生物伦理学培训计划，并同时解决临床研究中的生物伦理学，包括研究设计，统计分析，卫生经济学，健康差异以及健康信息访问和传播。通过在每个学术网站的专业知识和差异作用的基础上，我们提议从有限且经常轶事的表述过渡到多方面，多学科和强大的合作伙伴关系，以产生更大的结果性研究设计设计，从而构建了链接，以创造出比单个部分的更强的研究和培训更强的各个单个各个部分。我们假设一个基于社区的，证据，多学科的系统招聘和保留计划将导致招募和保留率不足的少数民族的招聘和保留，以产生足以实现临床试验目标的参与率。首席研究员/项目主管：威廉姆斯，路德·S。