CLEAN: A community-engaged intervention to increase colorectal cancer screening in Chinese American immigrants

CLEAN：社区参与的干预措施，以增加华裔美国移民的结直肠癌筛查

• 批准号: 10818709
• 负责人: Suzanne Sharry Vang
• 金额: $ 11.99万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-14 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10818709
• 关键词: CLEAN; community; engaged; intervention; increase

PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) is the second leading cause of cancer death among Chinese in the US. CRC screening prevents cancer and reduces mortality through the removal of precancerous polyps. However, CRC screening is severely underutilized by Chinese in the US with only 47% of Chinese Americans over age 50 reporting having ever completed a CRC screening compared to 73% of non-Hispanic whites. Given these disparities, it is critical to increase Chinese immigrants' participation in cancer prevention efforts. Research indicate community engaged interventions, such as narrative education and patient navigation are promising strategies for increasing CRC screening in vulnerable populations. In this study, we propose to develop and pilot test CoLorectal Cancer Narrative Education and Navigation (CLEAN), a community-engaged intervention consisting of narrative education and patient navigation to improve CRC screening in Chinese immigrants. To develop CLEAN, we will culturally and linguistically adapt Witness CARES, a theory-driven, evidence-based narrative group education program. We will also enhance the program with patient navigation to further promote CRC screening in this vulnerable population. Thus, our specific aims are to: (1) Develop CLEAN by culturally and linguistically adapting and enhancing Witness CARES to support CRC screening among Chinese immigrants; and (2) Pilot test the feasibility, acceptability, and preliminary efficacy of CLEAN for supporting CRC screening in Chinese immigrants. The long-term goal of the proposed research is to improve prevention and early detection of CRC in Chinese immigrants and other underserved groups with the ultimate objective of reducing cancer disparities. The proposed research is directly relevant to Dr. Vang's career goals and objectives and will be used to build a program of research to implement effective interventions aimed at reducing cancer disparities in minorities. Her research activities will be complemented with a well-thought out training plan that will help her acquire new knowledge and skills in: (1) community engaged research, and (2) and randomized controlled trials design and analysis. Given the institution's high quality research environment and resources, and with the guidance of the experienced mentoring team, Dr. Vang will have the support and resources necessary to successfully pursue the proposed research and training aims. Over the course of the 5-year funding period, she will participate in ongoing meetings with her mentors, complete formal coursework and interactive training activities offered at her institution and elsewhere; submit a minimum of 5 first author manuscripts for publication; and attend scientific research conferences to foster national networks with researchers in cancer health disparities. This multimodal training plan will provide Dr. Vang with the comprehensive skills needed to achieve her research aims and professional goal of becoming an independent behavioral health researcher.

项目概要/摘要 结直肠癌（CRC）是美国华人癌症死亡的第二大原因。 CRC 筛查通过切除癌前息肉来预防癌症并降低死亡率。然而，CRC 在美华人对筛查的利用严重不足，50 岁以上的华裔美国人中只有 47% 报告称曾经完成过 CRC 筛查，而非西班牙裔白人的这一比例为 73%。鉴于这些 差距，增加中国移民参与癌症预防工作至关重要。研究 表明社区参与的干预措施（例如叙事教育和患者导航）很有希望 加强弱势群体结直肠癌筛查的策略。在这项研究中，我们建议开发和 试点测试结直肠癌叙事教育和导航 (CLEAN)，一项社区参与的干预措施 包括叙事教育和患者导航，以改善中国移民的结直肠癌筛查。到 发展 CLEAN，我们将在文化和语言上适应 Witness CARES，这是一个理论驱动、基于证据的项目 叙事小组教育计划。我们还将通过患者导航来增强该计划，以进一步 促进这一弱势群体的结直肠癌筛查。因此，我们的具体目标是： (1) 开发 CLEAN 在文化和语言上进行调整和加强Witness CARES，以支持中国人的结直肠癌筛查 移民； （2）试点CLEAN支持的可行性、可接受性和初步成效 中国移民的CRC筛查。拟议研究的长期目标是改善预防 及早发现中国移民和其他服务不足的群体中的 CRC，最终目标是 减少癌症差异。拟议的研究与 Vang 博士的职业目标直接相关 目标，并将用于制定一项研究计划，以实施有效的干预措施，旨在 减少少数族裔的癌症差异。她的研究活动将得到深思熟虑的补充 培训计划将帮助她获得以下方面的新知识和技能：(1) 社区参与研究，以及 (2) 以及随机对照试验的设计和分析。鉴于该机构高质量的研究环境 和资源，并在经验丰富的导师团队的指导下，Vang博士将获得支持和 成功实现拟议研究和培训目标所需的资源。在整个过程中 5年资助期限，她将参加与导师正在进行的会议，完成正式课程 以及在她的机构和其他地方提供的互动培训活动；至少提交 5 位第一作者 供出版的手稿；并参加科学研究会议，以培育与 研究癌症健康差异的研究人员。该多模式培训计划将为 Vang 博士提供 实现她的研究目标和成为独立的专业目标所需的综合技能 行为健康研究员。