Patient Outcomes

患者结果

基本信息

批准号：
7838996
负责人：
KAREN M BASEN-ENGQUIST
金额：
$ 26.49万
依托单位：
DREXEL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-12-01 至 2014-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7838996
关键词：
Accounting Address Adherence Adverse effects Affect Africa Aftercare Algorithms Anti-Anxiety Agents Antibodies Anxiety Appalachian Region Area Asia Attitude Automation Behavioral Behavioral Research Belief Biopsy Canada Cancer Control Cancer Etiology Caring Case Study Cause of Death Certification Cervical Cervical Cancer Screening Cervical dysplasia Cervix Uteri China Client satisfaction Clinical Clinical Trials Clinical effectiveness Colposcopes Communication Communities Computer Assisted Contrast Media Country Cytology Data Decision Modeling Detection Developed Countries Developing Countries Development Devices Diagnosis Diagnostic Diagnostic Procedure Diffuse Distress Doctor of Philosophy Early Diagnosis Emerging Technologies Epidemiologist Epidemiology Europe Evaluation Fluorescence Future Goals Grant HPV-High Risk Health Health Care Costs Healthcare Histopathology Human Papilloma Virus Vaccine Human Papillomavirus Human papilloma virus infection Human papillomavirus 16 Image Imaging Device Institutes Intervention Knowledge Laboratories Lesion Life Literature Magnetic Resonance Imaging Mainstreaming Malignant neoplasm of cervix uteri Manuscripts Maps Measures Medical Medical Device Medical Technology Methodology Mexico Modeling Modification Molecular Molecular Diagnosis National Breast and Cervical Cancer Early Detection Program Nigeria Noise North America Optics Oral cavity Outcome Pain Pap smear Participant Pathology Patient Outcomes Assessments Patients Phase Play Postdoctoral Fellow Prevention Probability Procedures Process Provider Psychosocial Factor Recording of previous events Reporting Research Research Personnel Resources Role Rural Russia Scientist Screening for Oral Cancer Screening procedure Series Services South America South Texas Spectrum Analysis Students Surveys System Technology Technology Assessment Testing Texas Time Tissues Training Translational Research Treatment outcome United States Vaccines Validation Visit Well in self West Virginia Woman Writing clinical application clinical research site commercialization compliance behavior cost cost effectiveness design digital digital imaging follow-up health care delivery improved innovation mortality multidisciplinary new technology pilot trial population based prevent programs prophylactic psychological distress psychosocial routine practice satisfaction success symposium technological innovation technology development treatment adherence treatment program

项目摘要

The patient's perspective on the acceptability of technological innovation must be taken into account during the development of new technologies. Because patients are involved in their own care, medical devices that address their needs can produce better treatment outcomes. In this program project, we take a global approach to developing and assessing technologies to detect cervical cancer, considering factors at all levels that affect cervical screening and diagnosis: from the molecular to the patients and their communities. In Project 4, we will consider the effects of emerging technologies on patient outcomes in both developed and developing worlds. In developed countries, the multiple delays in the diagnosis and treatment trajectory after Papanicolaou smear and biopsy can reduce adherence and increase psychological distress for women receiving unfavorable results. In developing countries and underserved areas of the developed world, standard-of-care procedures require resources that are not available. In addition, cultural beliefs about screening for cervical cancer often exist that pose barriers to widespread screening programs. In this program project, we are developing technologies to address limitations in current technologies for both developed and developing countries. Emerging technologies under development with support from this grant aim to improve screening outcomes through (1) improved accuracy in less time, which can support diagnosis and treatment in a single visit; (2) more automation, facilitating wider use of the technology by non-expert providers; and (3) less invasive testing, which results in increased comfort and less distress for patients. To achieve the goals of Project 4, we take surveys of patient attitudes, distress, anxiety, pain, and priorities from 805 participants in the two clinical trials proposed in Project 3, which will be conducted at six clinical sites in Vancouver and Houston. We will also assess specific barriers to health care delivery in Appalachia, the Texas-Mexico border, and in Ibadan, Nigeria.

在开发新技术期间，必须考虑患者对技术创新可接受性的看法。由于患者参与自己的护理，因此可以满足其需求的医疗设备可以产生更好的治疗结果。在该计划项目中，我们采用一种全球方法来开发和评估技术以检测宫颈癌，考虑到影响宫颈筛查和诊断的各个层次的因素：从分子到患者及其社区。在项目4中，我们将考虑新兴技术对两者的患者结局的影响和发展中国家。在发达国家，Papanicolaou涂片和活检后的诊断和治疗轨迹的多个延迟可以减少依从性，并增加获得不利结果的女性的心理困扰。在发展中国家和发达国家服务不足的地区，护理标准程序需要无法提供的资源。此外，经常存在有关筛查宫颈癌筛查的文化信念，这些信念构成了广泛筛查计划的障碍。在此计划项目中，我们正在开发技术来解决发达国家和发展中国家当前技术的局限性。在此赠款的支持下，正在开发的新兴技术旨在通过（1）提高精度在更少的时间内提高筛查结果，这可以在一次访问中支持诊断和治疗；（2）更多的自动化，促进非专家提供商对技术的更广泛使用；（3）减少侵入性测试，从而增加舒适性和减少患者的困扰。为了实现项目4的目标，我们在项目3中提出的两项临床试验中的805名参与者中对患者态度，困扰，焦虑，痛苦以及优先事项进行了调查，该试验将在温哥华和休斯敦的六个临床场所进行。我们还将评估阿巴拉契亚州，德克萨斯州 - 墨西哥边境和尼日利亚伊巴丹的医疗保健提供的特定障碍。