INBRE: FURMAN U: FACULTY AND UNDERGRADUATE RESEARCH DEVELOPMENT

INBRE：弗尔曼大学：教师和本科生研究发展

• 批准号: 8168152
• 负责人: JOHN WHEELER
• 金额: $ 40.49万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-12 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168152
• 关键词: Applications Grants; Area; Arts; Award; Behavioral; Behavioral Medicine; Biology; Biomedical Research; Budgets; Chemistry; Cinnamon - dietary; Circular Dichroism; Commit; Computer Retrieval of Information on Scientific Projects Database; Contracts; Core Facility; Data; Development; Discipline; Educational process of instructing; Effectiveness; Enrollment; Environment; Equipment; Faculty; Fellowship; Funding; Grant; Growth; Historically Black Colleges and Universities; Housing; Individual; Institution; Joints; Lead; Maintenance; Measurement; Minority; Neurosciences; Population; Positioning Attribute; Psychology; Reporting; Research; Research Activity; Research Personnel; Research Proposals; Resources; Rice; Schedule; Science; Scientist; Source; South Carolina; Students; Talents; Time; Training; Underrepresented Minority; United States National Institutes of Health; Universities; Woman; Work; biological research; demographics; falls; improved; infrastructure development; instrument; instrumentation; member; operation; programs; research and development; square foot

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In addition to the individual research programs of our Target Faculty, Furman University has three primary subprojects as defined by our specific aims in the INBRE proposal. SUBPROJECT 1: Infrastructure Development and Research Capacity An important aim of the Furman University INBRE program is the development of infrastructure and core facilities to provide suitable resources and an appropriate environment for the most efficient and effective research program Furman can achieve as a liberal arts institution. Construction is currently in progress on the $60 million Townes Center for Science, with 75,000 square feet of new teaching and research space scheduled to become available in the summer of 2007. Furman was able to add an LC-MS instrument with joint University/NIH-BRIN funding in 2002 that is now heavily used by target faculty members Dr. Petty and Dr. Goess, the PI (Dr. John Wheeler), and Dr. Greg Springsteen, a Furman matching faculty member (see SUBPROJECT 2). A second critical equipment need was access to a flow cytometer in the Biology Department. Partial funding for this instrument was provided in YEAR 1, and the resulting instrument is now enjoying significant use by target faculty members Dr. Hestermann and Dr. Turgeon as well as other biological research faculty. A third major equipment acquisition will be the purchase of a circular dichroism spectrometer in YEAR 3 using partial INBRE funds. This acquisition will bolster the research efforts of Dr. Petty and also a recent tenure-track addition to the Chemistry Department, Dr. Karen Buchmuller, who begins her research program in the fall of 2007. A final aim of our INBRE program in the context of expanding Furman's research capacity is to provide a full-time scientist to oversee the daily operation, maintenance, and training of our high-value analytical equipment used by both the target faculty and other research faculty. Using 50% matching monies, a full-time staff scientist (Dr. Sandra Wheeler) has been employed on an academic year contract to manage these analytical operations over the first two years of the award. This position was strategically established to provide support during the most critical part of the year, when faculty members are less available for the considerable tasks associated with instrumentation maintenance and oversight. Dr. Wheeler has also served to assist target faculty in establishing new measurement capacities in their individual research programs as discussed in Section VI. SUBPROJECT 2: Faculty Development and New Target Faculty Positions A primary aim all INBRE activities is to assist and promote the development of the target faculty to a point where they mature into established independent investigators, at a minimum at the R15 level and for some faculty ultimately at the R01 level. Four target faculty were initially selected for participation in YEAR 1 of the INBRE award (Grisel, Hestermann, Petty and Turgeon), and since that time three of those faculty have been successful in competing for and receiving NIH R15 awards (Petty and Hestermann  YEAR 1; Grisel  YEAR 2). The fourth target faculty member, Dr. Turgeon, currently has an R15 application (resubmission from YEAR 1) pending, and we anticipate receiving her priority score within the next two months. As an additional part of its faculty development aims in the original proposal, Furman planned for an expansion position in the Psychology Department in the area of behavioral medicine in YEAR 2. The departure of one of our original target faculty (Dr. Moses Lee) prior to award made possible the addition of a second new target faculty member in the Chemistry Department in YEAR 2. The expansion position in behavioral medicine has been filled by Dr. Cinnamon Stetler (July 2006), and the replacement position in chemistry has been filled by Dr. Brian Goess (July 2006). The research plans and progress-to-date of these two new tenure-track additions is outlined in Section II of this report. In addition to the NIH-supported target faculty, Furman has made significant commitments to the development of other biomedical research faculty by establishing Furman INBRE Matching Fellowships. These pilot grants, awarded each summer to biomedical faculty showing promise of nationally competitive research activity, carry a summer stipend ($12,918), support for an undergraduate research student ($3,500) and a supplies budget ($3,000) to provide resources sufficient to help potential investigators obtain appropriate preliminary data for the submission of competitive NIH (or equivalent) research proposals. The two full INBRE matching awards from YEAR 1 each resulted in the submission of NIH grant proposals as noted in Section VI. Two awards were likewise made in YEAR 2 to junior faculty with similarly promising results as described in Section VI, and a call for proposals has been issued for a third year of matching fellowships for YEAR 3, with applications due in late February 2007. Finally, within the aim of the overall growth of our biomedical research faculty, Furman is committed to making significant efforts toward improving the distribution of underrepresented minorities among its faculty. An additional expansion position in neuroscience was added in July 2006, filled by Dr. Onarae Rice. Dr. Rice is a behavioral pharmacologist, and we anticipate he will substantively impact our effectiveness in attracting and retaining underrepresented student populations in the sciences in general and the rapidly emerging discipline of neuroscience in particular. SUBPROJECT 3: Student Development and Support Central to the overall aims of the South Carolina INBRE program is the development of a pipeline of promising new talent to carry forward the competitive research programs catalyzed by the INBRE funds. In YEAR 1, eleven undergraduate research students (7 women, 3 minority) were funded with NIH-INBRE resources to conduct full-time summer research with Furman target faculty. One additional minority student was funded from University INBRE matching funds to work with the Project Director, and two students (both women) were funded to work with each of two additional INBRE matching faculty (see SUBPROJECT 2). In YEAR 2, Furman was able to plan for the summer program more efficiently as a result of the additional lead time provided by the already-established award, and as a result the training of young scientists and involvement of students from underrepresented populations was even more successful than in the prior year. Given Furman's overall institutional demographics (approximately 12% minority enrollment institution-wide), a significant focus of the student training effort includes the participation of our target faculty in reaching out to faculty and students at each of South Carolina's Historically Black Colleges and Universities (HBCUs) to promote active participation in our research programs. Students who apply to the summer program from off-campus are provided with a full 10-week summer research stipend ($3,500) and also with housing in on-campus furnished apartments provided by Furman matching funds.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 除了我们目标学院的个人研究项目外，弗曼大学还根据我们在 INBRE 提案中的具体目标所定义的三个主要子项目。 子项目 1：基础设施发展和研究能力 弗曼大学INBRE项目的一个重要目标是开发基础设施和核心设施，为弗曼作为文科机构能够实现的最高效和最有效的研究项目提供合适的资源和适当的环境。 耗资 6,000 万美元的汤斯科学中心目前正在进行建设，预计将于 2007 年夏季投入使用 75,000 平方英尺的新教学和研究空间。弗曼与大学/NIH 联合添加了一台 LC-MS 仪器。 2002 年 BRIN 资助的资金现在被目标教员 Dr. Petty 和 Dr. Goess、PI（John Wheeler 博士）以及 Greg Springsteen 博士（弗曼匹配教员（参见子项目 2）。 第二个关键设备需求是生物系的流式细胞仪。 该仪器的部分资金是在第一年提供的，最终的仪器现在正被目标教员 Hestermann 博士和 Turgeon 博士以及其他生物研究教员广泛使用。 第三个主要设备采购是在第三年使用部分 INBRE 资金购买一台圆二色光谱仪。 此次收购将加强 Petty 博士以及最近加入化学系的终身教授 Karen Buchmuller 博士的研究工作，Karen Buchmuller 博士于 2007 年秋季开始她的研究计划。我们 INBRE 计划的最终目标扩大弗曼研究能力的目的是提供一名全职科学家来监督目标教师和其他研究教师使用的高价值分析设备的日常操作、维护和培训。 使用 50% 的配套资金，一名全职科学家（Sandra Wheeler 博士）已签订学年合同，在该奖项的前两年管理这些分析操作。 该职位的战略性设立是为了在一年中最关键的时期提供支持，当时教职员工无法完成与仪器维护和监督相关的大量任务。 惠勒博士还协助目标教师在其个人研究项目中建立新的测量能力，如第六节所述。 子项目 2：教师发展和新的教师目标职位 所有 INBRE 活动的主要目标是协助和促进目标教师的发展，使他们成熟为成熟的独立研究者，至少达到 R15 级别，某些教师最终达到 R01 级别。 四名目标教师最初被选为参加 INBRE 奖第一年（Grisel、Hestermann、Petty 和 Turgeon），从那时起，其中三名教师已成功竞争并获得 NIH R15 奖（Petty 和 Hestermann YEAR） 1；格里塞尔第二年）。 第四位目标教员 Turgeon 博士目前正在等待 R15 申请（从第一年重新提交），我们预计在接下来的两个月内收到她的优先分数。 作为最初提案中教师发展目标的另一部分，弗曼计划在第二年在心理学系的行为医学领域扩大职位。我们最初的目标教师之一（摩西·李博士）提前离开奖励使得第二年化学系增加了第二位新的目标教员。行为医学的扩展职位已由 Cinnamon Stetler 博士填补（2006 年 7 月），化学的替代职位已由Brian Goess 博士（2006 年 7 月）。 本报告第二节概述了这两项新的终身教授的研究计划和迄今为止的进展。 除了 NIH 支持的目标教师之外，弗曼还通过设立弗曼 INBRE 匹配奖学金，对其他生物医学研究教师的发展做出了重大承诺。这些试点补助金每年夏天颁发给生物医学教师，展示其在全国范围内具有竞争力的研究活动的前景，包括夏季津贴（12,918 美元）、对本科生研究生的支持（3,500 美元）和用品预算（3,000 美元），以提供足够的资源来帮助潜在的研究人员获取适当的初步数据以提交竞争性的 NIH（或同等机构）研究提案。 第一年的两个完整的 INBRE 匹配奖项均导致提交了 NIH 拨款提案，如第 VI 节所述。 同样，第二年还向初级教师颁发了两个奖项，其结果与第六节中所述的结果相似，并且已经为第三年的第三年匹配奖学金发出了征集建议，申请将于 2007 年 2 月下旬截止。最后，为了实现我们生物医学研究人员的整体发展，弗曼致力于做出重大努力，以改善其教师中代表性不足的少数族裔的分布。 2006 年 7 月，神经科学领域又增加了一个扩展职位，由 Onarae Rice 博士担任。 赖斯博士是一位行为药理学家，我们预计他将对我们吸引和留住科学领域、特别是快速新兴的神经科学学科中代表性不足的学生群体的有效性产生实质性影响。 子项目 3：学生发展和支持 南卡罗来纳州 INBRE 计划总体目标的核心是培养一批有前途的新人才，以推进由 INBRE 基金推动的竞争性研究项目。 第一年，11 名本科生（7 名女性，3 名少数族裔）获得 NIH-INBRE 资源的资助，与弗曼目标教师一起进行全日制暑期研究。 另外一名少数族裔学生获得大学 INBRE 配套资金的资助，与项目主任一起工作，两名学生（均为女性）获得资助，与另外两名 INBRE 配套教师中的每一位一起工作（见子项目 2）。 在第二年，由于已设立的奖项提供了额外的准备时间，弗曼能够更有效地规划夏季项目，因此，年轻科学家的培训和来自代表性不足人群的学生的参与更加充分比去年成功。 考虑到弗曼学院的总体人口统计数据（全校少数族裔入学率约为 12%），学生培训工作的一个重要重点包括让我们的目标教师参与接触南卡罗来纳州每所历史黑人学院和大学 (HBCU) 的教师和学生。 ）以促进积极参与我们的研究计划。 从校外申请暑期项目的学生将获得为期 10 周的暑期研究津贴（3,500 美元），并可入住由弗曼配套资金提供的配有家具的校内公寓。