Research Core

研究核心

基本信息

批准号：
10713131
负责人：
Emily Haroz
金额：
$ 55.68万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10713131
关键词：
Address Age Ally Area Automobile Driving Biological Models COVID-19 pandemic Code Collaborations Communities Data Data Collection Development Discipline Drug usage Ecosystem Epidemiology Equity Evaluation Extramural Activities Fostering Funding Future Gender Generations Health Heterogeneity Indigenous Inequity Institution Intervention Journals Leadership Measurement Measures Methodology Methods Modeling Morbidity - disease rate Native-Born Outcome Personal Satisfaction Persons Pharmaceutical Preparations Pilot Projects Policies Prevention Research Procedures Process Productivity Public Health Publications Race Recovery Research Research Design Research Methodology Research Personnel Research Project Grants Research Support Resource Sharing Resources Sea Services Source Statistical Data Interpretation System Training and Education Trauma United States Universities Work Writing addiction career community partnership data management data sharing design disparities in morbidity falls healing health inequalities implementation science indigenous community innovation intervention effect mortality mortality disparity novel outcome disparities personalized approach programs recruit repository student training substance abuse prevention substance use substance use prevention symposium web site

项目摘要

PROJECT SUMMARY Decades of research has failed to address Indigenous drug and other substance use inequities in the United States. These persistent challenges call for new systems and methods to turn the tide on Indigenous substance use prevention, programs, and policies. The Research Core will serve as a central resource for methods support and analyses for CIRCLE's proposed research and evaluation projects designed to build resources and evidence for culture as a core source of healing and prevention of substance use morbidity and mortality disparities resulting from centuries of colonizer-based racial trauma and oppression. The Research Core is led by a team of Indigenous and allied leadership who will provide operational support in Indigenous research methodologies; community partnership and culturally responsive engagement; substance use epidemiology; longitudinal, quantitative, qualitative, and mixed-methods analyses; multilevel and mixture modeling; implementation science; and data management, sovereignty, and stewardship in line with CIRCLE's overall aims and objectives. In addition, the Research Core will advance four methods innovation projects designed to: (1) conceptualize and operationalize “culture” as a key construct for addressing problematic substance use within and across Indigenous communities and settings; (2) characterize novel outcomes and measurement approaches for concepts of pre-addiction and recovery in Indigenous populations; (3) enhance understanding of heterogeneity in interventions, implementation, and policies to inform precision approaches to substance use research with Indigenous communities; and (4) operationalize the Indigenist Ecological Systems Model through creation of a repository of measures and associated resources. The Research Core will also support innovative pilot work by early-career investigators from diverse disciplines and helps them develop pilot research into robust lines of extramurally funded research. Finally, the Research Core will support dissemination of the CIRCLE's methodological advances and research findings in collaboration with the Administrative Core.

项目概要数十年的研究未能解决美国本土药物和其他物质使用的不平等问题这些持续存在的挑战需要新的系统和方法来扭转土著物质的潮流。使用预防、计划和政策。研究核心将作为方法支持的中心资源。对 CIRCLE 提议的旨在建立资源和证据的研究和评估项目进行分析将文化作为治疗和预防药物滥用发病率和死亡率差异的核心来源这是由于几个世纪以来殖民者的种族创伤和压迫造成的。研究核心由一个团队领导。土著和联盟领导层将在土著研究方法方面提供业务支持；社区伙伴关系和文化响应型参与；纵向、定性、定量和混合方法分析；多层次和混合建模；数据管理、主权和管理符合 CIRCLE 的总体宗旨和目标。此外，研究核心将推进四个方法创新项目，旨在：（1）概念化和将“文化”作为解决内部和外部物质使用问题的关键构建土著社区和环境；(2) 描述新的结果和衡量方法 (3)增强对异质性的认识在干预措施、实施和政策中，为物质使用研究的精确方法提供信息土著社区；(4) 通过创建土著生态系统模型来实施研究核心还将支持创新试点工作。来自不同学科的早期职业研究人员，并帮助他们将试点研究发展成强大的系列最后，研究核心将支持 CIRCLE 的传播。与行政核心合作的方法进展和研究成果。