Identifying Disparities in Type 2 Diabetes Among Asian Americans: The Pan Asian C

确定亚裔美国人 2 型糖尿病的差异：泛亚裔 C

• 批准号: 7850105
• 负责人: Latha P Palaniappan
• 金额: $ 5.56万
• 依托单位: PALO ALTO MEDICAL FOUNDATION RES INST
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-15 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7850105
• 关键词: Address; Adherence; Affect; Age; American; Asian Americans; Asian Indian; Asians; Attenuated; Body mass index; California; Cardiovascular Diseases; Caring; Chinese People; Clinical; Comorbidity; Complications of Diabetes Mellitus; Data; Databases; Decision Making; Demographic Factors; Diabetes Mellitus; Electronic Health Record; Environment; Epidemiologic Studies; Ethnic group; Filipino; Goals; Health; Healthcare; Healthcare Systems; Hypertension; Immigrant; Incidence; Individual; Japanese Population; Knowledge; Koreans; Language; Life; Link; Measures; Medical; Medicare; Minority Groups; Natural History; Non-Insulin-Dependent Diabetes Mellitus; Not Hispanic or Latino; Obesity; Outcome; Overweight; Pan Genus; Patient Self-Report; Patients; Physicians; Play; Population; Prediabetes syndrome; Preferred Provider Organizations; Prevalence; Preventive; Public Health; Research; Risk; Risk Factors; Role; Sampling; Screening procedure; Subgroup; Targeted Research; Testing; Time; World Health Organization; base; care seeking; cohort; comparison group; cost efficient; diabetes risk; diabetic; ethnic minority population; follow-up; health disparity; macrovascular disease; obesity risk; population based; prospective; public health relevance; racial/ethnic difference; sex

DESCRIPTION (provided by applicant): Although the Asian American population has grown dramatically in size and diversity in recent decades, there are wide gaps in our knowledge of health and healthcare for this population. Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese) are often aggregated in clinical and population-based studies because of small numbers in any one subgroup. In particular, data are lacking on Type 2 diabetes and obesity for Asian Americans, suggested to have increased risk of Type 2 diabetes. Moreover, no data explains whether this applies equally for all Asian American subgroups. The prevalence of obesity, pre-diabetes, diabetes and the diabetic complications of diabetes are largely unknown in specific Asian subgroups. There is also a controversy about how obesity should be defined for Asians. In 2004, the World Health Organization recommended lower body mass index (BMI) cut points to define overweight and obesity for people of Asian descent worldwide. However the evidence on which this is based is debatable, and it is possible that this association will be different in Asian subgroups living in the U.S. It is also unknown if risk factors for diabetes are similarly predictive for Asian American subgroups and Non-Hispanic Whites (NHWs). Better information is needed concerning screening, incidence, prevalence, risk factors, natural history of obesity and diabetes, and healthcare and patient factors that affect treatment disparities for Asian American subgroups. This application aims to examine diabetes screening, risk and care both to fill gaps in knowledge of diabetes disparities and to inform clinical decision making regarding screening and healthcare for Asian Americans. We propose to construct a mixed historical and prospective longitudinal cohort by linking existing clinical databases in a large (20,000), multiethnic sample of contemporary Asians in California. We will define Asian subgroups through self-report, and will include a sample of NHWs for comparison. Use of electronic health records in this epidemiologic study will allow highly cost efficient assembly and follow-up of this cohort. The overall goal of this application is to address a substantial gap in existing knowledge regarding diabetes risk in Asian racial/ethnic minorities. This study will provide a greater understanding of diabetes among Asian ethnic minorities in a comparable environment, and would contribute both to a global understanding of risk for Asian populations and to more targeted research, public health and clinical efforts throughout the U.S. PUBLIC HEALTH RELEVANCE Limited information is available about diabetes among Asians, one of the nation's fastest growing minority groups. The overall goal of this application is to address a substantial gap in existing knowledge about diabetes in Asians. This application will provide a greater understanding of diabetes among Asian racial/ethnic minorities and would contribute to targeted research, public health, and clinical efforts throughout the U.S.

描述（由申请人提供）：尽管亚裔美国人的人口在近几十年来的规模和多样性急剧增长，但我们对这一人群的健康和医疗保健知识存在很大差异。亚洲亚组（亚洲印第安人，中国，菲律宾，日本，韩国和越南人）通常在临床和人群研究中汇总，因为任何一个亚组中的数量很少。特别是，对于亚裔美国人的2型糖尿病和肥胖症缺乏数据，该数据建议增加2型糖尿病的风险。此外，没有数据可以解释这是否适用于所有亚裔美国亚裔亚组。在特定的亚洲亚组中，肥胖，糖尿病前，糖尿病和糖尿病并发症的患病率在很大程度上是未知的。关于如何为亚洲人定义肥胖，也存在一个争议。 2004年，世界卫生组织建议下体重指数（BMI）切点，以定义全球亚洲血统的人的超重和肥胖。但是，基于此基础的证据是有争议的，并且在美国生活的亚洲亚组中，这种关联可能会有所不同。糖尿病的危险因素是否同样可以预测亚裔美国人亚组和非西班牙裔白人（NHWS），这也尚不清楚。需要更好的信息，以了解筛查，发病率，危险因素，肥胖和糖尿病的自然史以及影响亚裔美国亚裔亚组治疗差异的医疗保健和患者因素。该应用程序旨在检查糖尿病筛查，风险和护理，以填补糖尿病差异知识的空白，并为亚裔美国人的筛查和医疗保健提供临床决策。我们建议通过将现有的临床数据库（20,000）（20,000），当代亚洲人在加利福尼亚州的当代亚洲人样本联系起来，构建一个混合的历史和前瞻性纵向队列。我们将通过自我报告定义亚洲亚组，并包括一个NHW的样本以进行比较。在这项流行病学研究中，电子健康记录的使用将允许高度成本高效的组装和随访该队列。该应用程序的总体目标是解决有关亚洲种族/族裔少数民族糖尿病风险的现有知识的巨大差距。这项研究将在可比的环境中对亚洲少数民族中的糖尿病有更多的了解，并将为全球对亚洲人群的风险做出贡献，以及在美国公共卫生相关性的更有针对性的研究，公共卫生和临床努力有限的信息有限的信息中，这是美国亚洲人的糖尿病信息，这是美国糖尿病的，这是全国最快成长的少数群体中最快的少数群体之一。该应用程序的总体目标是解决有关亚洲人糖尿病的现有知识的巨大差距。该申请将对亚洲种族/族裔少数民族中的糖尿病有更多的了解，并将为全美的有针对性的研究，公共卫生和临床工作做出贡献。